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| α-Synuclein impairs macroautophagy: implications for Parkinson’s disease AR Winslow, CW Chen, S Corrochano, A Acevedo-Arozena, DE Gordon, ... Journal of Cell Biology 190 (6), 1023-1037, 2010 | 980 | 2010 |
| Dynein mutations impair autophagic clearance of aggregate-prone proteins B Ravikumar, A Acevedo-Arozena, S Imarisio, Z Berger, C Vacher, ... Nature genetics 37 (7), 771-776, 2005 | 569 | 2005 |
| Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease C Rose, FM Menzies, M Renna, A Acevedo-Arozena, S Corrochano, ... Human molecular genetics 19 (11), 2144-2153, 2010 | 241 | 2010 |
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| SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments PI Joyce, P Fratta, EMC Fisher, A Acevedo-Arozena Mammalian Genome 22, 420-448, 2011 | 170 | 2011 |
| Mice with endogenous TDP‐43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis P Fratta, P Sivakumar, J Humphrey, K Lo, T Ricketts, H Oliveira, ... The EMBO journal 37 (11), e98684, 2018 | 163 | 2018 |
| A comprehensive assessment of the SOD1G93A low-copy transgenic mouse, which models human amyotrophic lateral sclerosis A Acevedo-Arozena, B Kalmar, S Essa, T Ricketts, P Joyce, R Kent, ... Disease models & mechanisms 4 (5), 686-700, 2011 | 133 | 2011 |
| Analysis of individual mouse activity in group housed animals of different inbred strains using a novel automated home cage analysis system RS Bains, HL Cater, RR Sillito, A Chartsias, D Sneddon, D Concas, ... Frontiers in behavioral neuroscience 10, 106, 2016 | 127 | 2016 |
| Humanized mutant FUS drives progressive motor neuron degeneration without aggregation in ‘FUSDelta14’knockin mice A Devoy, B Kalmar, M Stewart, H Park, B Burke, SJ Noy, Y Redhead, ... Brain 140 (11), 2797-2805, 2017 | 125 | 2017 |
| Novel gene function revealed by mouse mutagenesis screens for models of age-related disease PK Potter, MR Bowl, P Jeyarajan, L Wisby, A Blease, ME Goldsworthy, ... Nature communications 7 (1), 12444, 2016 | 99 | 2016 |
| Transgenic and physiological mouse models give insights into different aspects of amyotrophic lateral sclerosis F De Giorgio, C Maduro, EMC Fisher, A Acevedo-Arozena Disease models & mechanisms 12 (1), dmm037424, 2019 | 90 | 2019 |
| IGF-1 receptor antagonism inhibits autophagy M Renna, CF Bento, A Fleming, FM Menzies, FH Siddiqi, B Ravikumar, ... Human molecular genetics 22 (22), 4528-4544, 2013 | 88 | 2013 |
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| Dyneins, autophagy, aggregation and neurodegeneration DC Rubinsztein, B Ravikumar, A Acevedo-Arozena, S Imarisio, ... Autophagy 1 (3), 177-178, 2005 | 74 | 2005 |
| A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity PI Joyce, P Mcgoldrick, RA Saccon, W Weber, P Fratta, SJ West, N Zhu, ... Human molecular genetics 24 (7), 1883-1897, 2015 | 69 | 2015 |
| Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease H Tateossian, S Morse, A Parker, P Mburu, N Warr, A Acevedo-Arozena, ... Human molecular genetics 22 (13), 2553-2565, 2013 | 69 | 2013 |
| EFL1 mutations impair eIF6 release to cause Shwachman-Diamond syndrome S Tan, L Kermasson, A Hoslin, P Jaako, A Faille, A Acevedo-Arozena, ... Blood, The Journal of the American Society of Hematology 134 (3), 277-290, 2019 | 58 | 2019 |
| Haplotype sharing suggests that a genomic segment containing six genes accounts for the pulmonary adenoma susceptibility 1 (Pas1) locus activity in mice G Manenti, F Galbiati, R Gianni-Barrera, A Pettinicchio, A Acevedo, ... Oncogene 23 (25), 4495-4504, 2004 | 56 | 2004 |
| Loss-of-function mutations in FRRS1L lead to an epileptic-dyskinetic encephalopathy M Madeo, M Stewart, Y Sun, N Sahir, S Wiethoff, I Chandrasekar, ... The American Journal of Human Genetics 98 (6), 1249-1255, 2016 | 50 | 2016 |
David RubinszteinUniversity of CambridgeVerified email at cam.ac.uk
