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Weiguang Wang
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Disulfiram modulated ROS–MAPK and NFκB pathways and targeted breast cancer cells with cancer stem cell-like properties
NC Yip, IS Fombon, P Liu, S Brown, V Kannappan, AL Armesilla, B Xu, ...
British journal of cancer 104 (10), 1564-1574, 2011
4192011
Cytotoxic effect of disulfiram/copper on human glioblastoma cell lines and ALDH-positive cancer-stem-like cells
P Liu, S Brown, T Goktug, P Channathodiyil, V Kannappan, JP Hugnot, ...
British journal of cancer 107 (9), 1488-1497, 2012
3232012
Disulfiram‐mediated inhibition of NF‐κB activity enhances cytotoxicity of 5‐fluorouracil in human colorectal cancer cell lines
W Wang, HL McLeod, J Cassidy
International journal of cancer 104 (4), 504-511, 2003
2862003
Disulfiram targets cancer stem-like cells and reverses resistance and cross-resistance in acquired paclitaxel-resistant triple-negative breast cancer cells
P Liu, IS Kumar, S Brown, V Kannappan, PE Tawari, JZ Tang, W Jiang, ...
British journal of cancer 109 (7), 1876-1885, 2013
1902013
Disulfiram/copper complex inhibiting NFκB activity and potentiating cytotoxic effect of gemcitabine on colon and breast cancer cell lines
X Guo, B Xu, S Pandey, E Goessl, J Brown, AL Armesilla, JL Darling, ...
Cancer letters 290 (1), 104-113, 2010
1562010
ALDH1A1 defines invasive cancer stem-like cells and predicts poor prognosis in patients with esophageal squamous cell carcinoma
L Yang, Y Ren, X Yu, F Qian, H Xiao, W Wang, S Xu, J Yang, W Cui, Q Liu, ...
Modern Pathology 27 (5), 775-783, 2014
1522014
Mechanistic and predictive profiling of 5-Fluorouracil resistance in human cancer cells
W Wang, J Cassidy, V O’Brien, KM Ryan, E Collie-Duguid
Cancer research 64 (22), 8167-8176, 2004
1432004
Liposome encapsulated Disulfiram inhibits NFκB pathway and targets breast cancer stem cells in vitro and in vivo
P Liu, Z Wang, S Brown, V Kannappan, PE Tawari, W Jiang, JM Irache, ...
Oncotarget 5 (17), 7471, 2014
1282014
Disulfiram/copper selectively eradicates AML leukemia stem cells in vitro and in vivo by simultaneous induction of ROS-JNK and inhibition of NF-κB and Nrf2
B Xu, S Wang, R Li, K Chen, L He, M Deng, V Kannappan, J Zha, H Dong, ...
Cell death & disease 8 (5), e2797-e2797, 2017
1192017
Disulfiram targeting lymphoid malignant cell lines via ROS-JNK activation as well as Nrf2 and NF-kB pathway inhibition
J Zha, F Chen, H Dong, P Shi, Y Yao, Y Zhang, R Li, S Wang, P Li, ...
Journal of translational medicine 12, 1-9, 2014
1052014
Pharmacogenomic dissection of resistance to thymidylate synthase inhibitors
W Wang, S Marsh, J Cassidy, HL McLeod
Cancer research 61 (14), 5505-5510, 2001
982001
Insulin-like growth factor II and PAX3-FKHR cooperate in the oncogenesis of rhabdomyosarcoma
W Wang, P Kumar, W Wang, J Epstein, L Helman, JV Moore, S Kumar
Cancer research 58 (19), 4426-4433, 1998
901998
Poly lactic-co-glycolic acid controlled delivery of disulfiram to target liver cancer stem-like cells
Z Wang, J Tan, C McConville, V Kannappan, PE Tawari, J Brown, J Ding, ...
Nanomedicine: Nanotechnology, Biology and Medicine 13 (2), 641-657, 2017
882017
The cytotoxic mechanisms of disulfiram and copper (ii) in cancer cells
PE Tawari, Z Wang, M Najlah, CW Tsang, V Kannappan, P Liu, ...
Toxicology research 4 (6), 1439-1442, 2015
872015
Cell cycle perturbation and acquired 5-fluorouracil chemoresistance
X Guo, E Goessl, G Jin, ESR Collie-Duguid, J Cassidy, W Wang, ...
Anticancer research 28 (1A), 9-14, 2008
752008
Low-dose triptolide in combination with idarubicin induces apoptosis in AML leukemic stem-like KG1a cell line by modulation of the intrinsic and extrinsic factors
Y Liu, F Chen, S Wang, X Guo, P Shi, W Wang, B Xu
Cell death & disease 4 (12), e948-e948, 2013
682013
Endothelial nitric oxide synthase activity is inhibited by the plasma membrane calcium ATPase in human endothelial cells
ML Holton, TMA Mohamed, D Oceandy, W Wang, S Lamas, M Emerson, ...
Cardiovascular research 87 (3), 440-448, 2010
682010
Recent advances in repurposing disulfiram and disulfiram derivatives as copper-dependent anticancer agents
V Kannappan, M Ali, B Small, G Rajendran, S Elzhenni, H Taj, W Wang, ...
Frontiers in Molecular Biosciences 8, 741316, 2021
672021
A new strategy to target acute myeloid leukemia stem and progenitor cells using chidamide, a histone deacetylase inhibitor
Y Li, K Chen, Y Zhou, Y Xiao, M Deng, Z Jiang, W Ye, X Wang, X Wei, J Li, ...
Current cancer drug targets 15 (6), 493-503, 2015
662015
Disulfiram/copper complex activated JNK/c-jun pathway and sensitized cytotoxicity of doxorubicin in doxorubicin resistant leukemia HL60 cells
B Xu, P Shi, IS Fombon, Y Zhang, F Huang, W Wang, S Zhou
Blood Cells, Molecules, and Diseases 47 (4), 264-269, 2011
662011
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