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Sameer Doshi
Sameer Doshi
Verified email at amgen.com
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Year
Blinatumomab, a Bispecific T-cell Engager (BiTE®) for CD-19 Targeted Cancer Immunotherapy: Clinical Pharmacology and Its Implications
M Zhu, B Wu, C Brandl, J Johnson, A Wolf, A Chow, S Doshi
Clinical pharmacokinetics 55, 1271-1288, 2016
1732016
Population pharmacokinetic meta-analysis of denosumab in healthy subjects and postmenopausal women with osteopenia or osteoporosis
L Sutjandra, RD Rodriguez, S Doshi, M Ma, MC Peterson, GR Jang, ...
Clinical pharmacokinetics 50, 793-807, 2011
1032011
Population pharmacokinetic analysis of denosumab in patients with bone metastases from solid tumours
L Gibiansky, L Sutjandra, S Doshi, J Zheng, W Sohn, MC Peterson, ...
Clinical pharmacokinetics 51, 247-260, 2012
812012
Pharmacodynamics-mediated drug disposition (PDMDD) and precursor pool lifespan model for single dose of romiplostim in healthy subjects
YMC Wang, W Krzyzanski, S Doshi, JJ Xiao, JJ Pérez-Ruixo, AT Chow
The AAPS journal 12, 729-740, 2010
762010
Population pharmacokinetics of rilotumumab, a fully human monoclonal antibody against hepatocyte growth factor, in cancer patients
M Zhu, S Doshi, PO Gisleskog, KS Oliner, JJP Ruixo, E Loh, Y Zhang
Journal of Pharmaceutical Sciences 103 (1), 328-336, 2014
682014
Investigation of the effects of altered receptor binding activity on the clearance of erythropoiesis-stimulating proteins: nonerythropoietin receptor-mediated pathways may play …
B Agoram, K Aoki, S Doshi, C Gegg, G Jang, G Molineux, L Narhi, S Elliott
Journal of pharmaceutical sciences 98 (6), 2198-2211, 2009
482009
Rilotumumab exposure–response relationship in patients with advanced or metastatic gastric cancer
S Doshi, PO Gisleskog, Y Zhang, M Zhu, KS Oliner, E Loh, JJP Ruixo
Clinical Cancer Research 21 (11), 2453-2461, 2015
452015
Exposure-response analysis of rilotumumab in gastric cancer: the role of tumour MET expression
M Zhu, R Tang, S Doshi, KS Oliner, S Dubey, Y Jiang, RC Donehower, ...
British journal of cancer 112 (3), 429-437, 2015
452015
Impact of target‐mediated elimination on the dose and regimen of evolocumab, a human monoclonal antibody against proprotein convertase subtilisin/kexin type 9 (PCSK9)
JP Gibbs, S Doshi, M Kuchimanchi, A Grover, MG Emery, MG Dodds, ...
The Journal of Clinical Pharmacology 57 (5), 616-626, 2017
442017
Pharmacodynamics of romiplostim alone and in combination with pegfilgrastim on acute radiation-induced thrombocytopenia and neutropenia in non-human primates
K Wong, PY Chang, M Fielden, AM Downey, D Bunin, J Bakke, ...
International journal of radiation biology 96 (1), 155-166, 2020
362020
Tumor penetration and epidermal growth factor receptor saturation by panitumumab correlate with antitumor activity in a preclinical model of human cancer
DJ Freeman, K McDorman, S Ogbagabriel, C Kozlosky, BB Yang, S Doshi, ...
Molecular Cancer 11, 1-11, 2012
352012
Denosumab dose selection for patients with bone metastases from solid tumors
S Doshi, L Sutjandra, J Zheng, W Sohn, M Peterson, G Jang, AT Chow, ...
Clinical Cancer Research 18 (9), 2648-2657, 2012
302012
Blinatumomab pharmacodynamics and exposure–response relationships in relapsed/refractory acute lymphoblastic leukemia
M Zhu, A Kratzer, J Johnson, C Holland, C Brandl, I Singh, A Wolf, ...
The Journal of Clinical Pharmacology 58 (2), 168-179, 2018
292018
Exposure‐response modeling of darbepoetin alfa in anemic patients with chronic kidney disease not receiving dialysis
S Doshi, A Chow, JJP Ruixo
The Journal of Clinical Pharmacology 50 (S9), 75S-90S, 2010
252010
Clinical pharmacokinetics and pharmacodynamics of erythropoiesis-stimulating agents
S Doshi, W Krzyzanski, S Yue, S Elliott, A Chow, JJ Pérez-Ruixo
Clinical pharmacokinetics 52, 1063-1083, 2013
212013
Comparison of LDL-C reduction using different evolocumab doses and intervals: biological insights and treatment implications
SM Wasserman, MS Sabatine, MJ Koren, RP Giugliano, JC Legg, ...
Journal of Cardiovascular Pharmacology and Therapeutics 23 (5), 423-432, 2018
162018
Development of romiplostim for treatment of primary immune thrombocytopenia from a pharmacokinetic and pharmacodynamic perspective
BB Yang, S Doshi, K Arkam, J Franklin, AT Chow
Clinical Pharmacokinetics 55, 1045-1058, 2016
152016
Population pharmacokinetics of blinatumomab in pediatric and adult patients with hematological malignancies
JD Clements, M Zhu, M Kuchimanchi, B Terminello, S Doshi
Clinical pharmacokinetics 59, 463-474, 2020
142020
Romiplostim dose response in patients with immune thrombocytopenia
JJ Perez‐Ruixo, B Green, S Doshi, YM Wang, DR Mould
The Journal of Clinical Pharmacology 52 (10), 1540-1551, 2012
142012
Pharmacokinetics and pharmacodynamics of rilotumumab: a decade of experience in preclinical and clinical cancer research
Y Zhang, S Doshi, M Zhu
British journal of clinical pharmacology 80 (5), 957-964, 2015
132015
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