Rafael Fridman
Rafael Fridman
Professor of Pathology & Oncology, Wayne State University
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Endothelial cell-derived basic fibroblast growth factor: synthesis and deposition into subendothelial extracellular matrix.
I Vlodavsky, J Folkman, R Sullivan, R Fridman, R Ishai-Michaeli, J Sasse, ...
Proceedings of the National Academy of Sciences 84 (8), 2292-2296, 1987
Matrix metalloproteinases: structures, evolution, and diversification
I Massova, LP Kotra, R Fridman, S Mobashery
The FASEB Journal 12 (12), 1075-1095, 1998
A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia
Z Gu, J Cui, S Brown, R Fridman, S Mobashery, AY Strongin, SA Lipton
Journal of Neuroscience 25 (27), 6401-6408, 2005
Increased expression of matrix metalloproteinases (MMP)-2, MMP-9, and the urokinase-type plasminogen activator is associated with progression from benign to advanced ovarian cancer
B Schmalfeldt, D Prechtel, K Härting, K Späthe, S Rutke, E Konik, ...
Clinical Cancer Research 7 (8), 2396-2404, 2001
Matrix metalloproteinase 2 releases active soluble ectodomain of fibroblast growth factor receptor 1.
E Levi, R Fridman, HQ Miao, YS Ma, A Yayon, I Vlodavsky
Proceedings of the National Academy of Sciences 93 (14), 7069-7074, 1996
Activation of progelatinase B (MMP-9) by gelatinase A (MMP-2)
R Fridman, M Toth, D Peņa, S Mobashery
Cancer research 55 (12), 2548-2555, 1995
Discoidin domain receptor tyrosine kinases: new players in cancer progression
RR Valiathan, M Marco, B Leitinger, CG Kleer, R Fridman
Cancer and Metastasis Reviews 31, 295-321, 2012
Binding of active (57 kDa) membrane type 1-matrix metalloproteinase (MT1-MMP) to tissue inhibitor of metalloproteinase (TIMP)-2 regulates MT1-MMP processing and pro-MMP-2 …
S Hernandez-Barrantes, M Toth, MM Bernardo, M Yurkova, DC Gervasi, ...
Journal of Biological Chemistry 275 (16), 12080-12089, 2000
Identification of CD63 as a tissue inhibitor of metalloproteinase‐1 interacting cell surface protein
KK Jung, XW Liu, R Chirco, R Fridman, HRC Kim
The EMBO journal 25 (17), 3934-3942, 2006
Kinetic analysis of the binding of human matrix metalloproteinase-2 and-9 to tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2
MW Olson, DC Gervasi, S Mobashery, R Fridman
Journal of Biological Chemistry 272 (47), 29975-29983, 1997
Type IV collagenase (s) and TIMPs modulate endothelial cell morphogenesis in vitro
HW Schnaper, DS Grant, WG Stetler‐Stevenson, R Fridman, G D'Orazi, ...
Journal of cellular physiology 156 (2), 235-246, 1993
Galectin-3 is a novel substrate for human matrix metalloproteinases-2 and-9
J Ochieng, R Fridman, P Nangia-Makker, DE Kleiner, LA Liotta, ...
Biochemistry 33 (47), 14109-14114, 1994
Tissue inhibitor of metalloproteinase-1 inhibits apoptosis of human breast epithelial cells
G Li, R Fridman, HRC Kim
Cancer research 59 (24), 6267-6275, 1999
Assessment of gelatinases (MMP-2 and MMP-9) by gelatin zymography
M Toth, A Sohail, R Fridman
Metastasis research protocols, 121-135, 2012
Reconstituted basement membrane (matrigel) and laminin can enhance the tumorigenicity and the drug resistance of small cell lung cancer cell lines.
R Fridman, G Giaccone, T Kanemoto, GR Martin, AF Gazdar, JL Mulshine
Proceedings of the National Academy of Sciences 87 (17), 6698-6702, 1990
High levels of tissue inhibitor of metalloproteinase-2 (TIMP-2) expression are associated with poor outcome in invasive bladder cancer
DJ Grignon, W Sakr, M Toth, V Ravery, J Angulo, F Shamsa, JE Pontes, ...
Cancer Research 56 (7), 1654-1659, 1996
Epidermal growth factor and amphiregulin up‐regulate matrix metalloproteinase‐9 (MMP‐9) in human breast cancer cells
SB Kondapaka, R Fridman, KB Reddy
International journal of cancer 70 (6), 722-726, 1997
Assessment of gelatinases (MMP-2 and MMP-9 by gelatin zymography
M Toth, R Fridman
Metastasis Research Protocols: Volume I: Analysis of Cells and Tissues, 163-174, 2001
Matrix metalloproteinase activity, bone matrix turnover, and tumor cell proliferation in prostate cancer bone metastasis
JA Nemeth, R Yousif, M Herzog, M Che, J Upadhyay, B Shekarriz, ...
Journal of the National Cancer Institute 94 (1), 17-25, 2002
Domain structure of human 72-kDa gelatinase/type IV collagenase. Characterization of proteolytic activity and identification of the tissue inhibitor of metalloproteinase-2 …
R Fridman, TR Fuerst, RE Bird, M Hoyhtya, M Oelkuct, S Kraus, ...
Journal of Biological Chemistry 267 (22), 15398-15405, 1992
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