| Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3 MD Shahbazian, JI Young, LA Yuva-Paylor, CM Spencer, BA Antalffy, ... Neuron 35 (2), 243-254, 2002 | 906 | 2002 |
| Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2 JI Young, EP Hong, JC Castle, J Crespo-Barreto, AB Bowman, MF Rose, ... Proceedings of the national academy of sciences 102 (49), 17551-17558, 2005 | 552 | 2005 |
| Regulation of the epigenome by vitamin C JI Young, S Züchner, G Wang Annual review of nutrition 35, 545-564, 2015 | 340 | 2015 |
| Ascorbate induces Ten-Eleven Translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine*♦ EA Minor, JI Young, G Wang Journal of Biological Chemistry 288 (19), 13669-13674, 2013 | 334 | 2013 |
| Mutations in ANKRD11 cause KBG syndrome, characterized by intellectual disability, skeletal malformations, and macrodontia A Sirmaci, M Spiliopoulos, F Brancati, E Powell, D Duman, A Abrams, ... The American Journal of Human Genetics 89 (2), 289-294, 2011 | 258 | 2011 |
| Whole-exome sequencing links a variant in DHDDS to retinitis pigmentosa S Züchner, J Dallman, R Wen, G Beecham, A Naj, A Farooq, MA Kohli, ... The American Journal of Human Genetics 88 (2), 201-206, 2011 | 189 | 2011 |
| A role for the endogenous opioid β-endorphin in energy homeostasis SM Appleyard, M Hayward, JI Young, AA Butler, RD Cone, M Rubinstein, ... Endocrinology 144 (5), 1753-1760, 2003 | 183 | 2003 |
| X-chromosome inactivation patterns are unbalanced and affect the phenotypic outcome in a mouse model of rett syndrome JI Young, HY Zoghbi The American Journal of Human Genetics 74 (3), 511-520, 2004 | 179 | 2004 |
| Podocyte-specific overexpression of wild type or mutant trpc6 in mice is sufficient to cause glomerular disease P Krall, CP Canales, P Kairath, P Carmona-Mora, J Molina, JD Carpio, ... PloS one 5 (9), e12859, 2010 | 149 | 2010 |
| Absence of dopamine D4 receptors results in enhanced reactivity to unconditioned, but not conditioned, fear TL Falzone, DM Gelman, JI Young, DK Grandy, MJ Low, M Rubinstein European Journal of Neuroscience 15 (1), 158-164, 2002 | 143 | 2002 |
| Mutations in OTOGL, encoding the inner ear protein otogelin-like, cause moderate sensorineural hearing loss KO Yariz, D Duman, CZ Seco, J Dallman, M Huang, TA Peters, A Sirmaci, ... The American Journal of Human Genetics 91 (5), 872-882, 2012 | 122 | 2012 |
| Phenotypic consequences of copy number variation: insights from Smith-Magenis and Potocki-Lupski syndrome mouse models G Ricard, J Molina, J Chrast, W Gu, N Gheldof, S Pradervand, F Schütz, ... PLoS biology 8 (11), e1000543, 2010 | 113 | 2010 |
| Ascorbate-induced generation of 5-hydroxymethylcytosine is unaffected by varying levels of iron and 2-oxoglutarate KM Dickson, CB Gustafson, JI Young, S Züchner, G Wang Biochemical and biophysical research communications 439 (4), 522-527, 2013 | 92 | 2013 |
| Ischemic preconditioning alters the epigenetic profile of the brain from ischemic intolerance to ischemic tolerance JW Thompson, KR Dave, JI Young, MA Perez-Pinzon Neurotherapeutics 10 (4), 789-797, 2013 | 92 | 2013 |
| Authentic cell-specific and developmentally regulated expression of pro-opiomelanocortin genomic fragments in hypothalamic and hindbrain neurons of transgenic mice JI Young, V Otero, MG Cerdan, TL Falzone, EC Chan, MJ Low, ... Journal of Neuroscience 18 (17), 6631-6640, 1998 | 91 | 1998 |
| The Expanding Role of MBD Genes in Autism: Identification of a MECP2 Duplication and Novel Alterations in MBD5, MBD6, and SETDB1 HN Cukier, JM Lee, D Ma, JI Young, V Mayo, BL Butler, SS Ramsook, ... Autism research 5 (6), 385-397, 2012 | 90 | 2012 |
| Cell-specific expression of wild-type MeCP2 in mouse models of Rett syndrome yields insight about pathogenesis M Alvarez-Saavedra, MA Sáez, D Kang, HY Zoghbi, JI Young Human molecular genetics 16 (19), 2315-2325, 2007 | 89 | 2007 |
| Defective body-weight regulation, motor control and abnormal social interactions in Mecp2 hypomorphic mice B Kerr, M Alvarez-Saavedra, MA Sáez, A Saona, JI Young Human molecular genetics 17 (12), 1707-1717, 2008 | 86 | 2008 |
| DNA methyltransferase inhibition in normal human fibroblasts induces a p21-dependent cell cycle withdrawal JI Young, JR Smith Journal of Biological Chemistry 276 (22), 19610-19616, 2001 | 86 | 2001 |
| Resveratrol preconditioning induces a novel extended window of ischemic tolerance in the mouse brain KB Koronowski, KR Dave, I Saul, V Camarena, JW Thompson, ... Stroke 46 (8), 2293-2298, 2015 | 85 | 2015 |
