Follow
mathy froeyen
mathy froeyen
Verified email at rega.kuleuven.be
Title
Cited by
Cited by
Year
Structural elucidation of SARS-CoV-2 vital proteins: Computational methods reveal potential drug candidates against main protease, Nsp12 polymerase and Nsp13 helicase
MU Mirza, M Froeyen
Journal of pharmaceutical analysis 10 (4), 320-328, 2020
2822020
Mutations in the chikungunya virus non-structural proteins cause resistance to favipiravir (T-705), a broad-spectrum antiviral
L Delang, N Segura Guerrero, A Tas, G Quérat, B Pastorino, M Froeyen, ...
Journal of Antimicrobial Chemotherapy 69 (10), 2770-2784, 2014
2492014
Cyclohexene nucleic acids (CeNA): serum stable oligonucleotides that activate RNase H and increase duplex stability with complementary RNA
J Wang, B Verbeure, I Luyten, E Lescrinier, M Froeyen, C Hendrix, ...
Journal of the American Chemical Society 122 (36), 8595-8602, 2000
1952000
Novel inhibitors of influenza virus fusion: structure-activity relationship and interaction with the viral hemagglutinin
E Vanderlinden, F Göktaş, Z Cesur, M Froeyen, ML Reed, CJ Russell, ...
Journal of virology 84 (9), 4277-4288, 2010
1722010
Carbohydrate-binding agents cause deletions of highly conserved glycosylation sites in HIV GP120: a new therapeutic concept to hit the achilles heel of HIV
J Balzarini, K Van Laethem, S Hatse, M Froeyen, W Peumans, ...
Journal of Biological Chemistry 280 (49), 41005-41014, 2005
1572005
Molecular dynamics simulation of polarizable water by an extended Lagrangian method
D Van Belle, M Froeyen, G Lippens, SJ Wodak
Molecular physics 77 (2), 239-255, 1992
1421992
Deoxythreosyl phosphonate nucleosides as selective anti-HIV agents
T Wu, M Froeyen, V Kempeneers, C Pannecouque, J Wang, R Busson, ...
Journal of the American Chemical Society 127 (14), 5056-5065, 2005
1382005
Pharmacoinformatics and molecular dynamics simulation studies reveal potential covalent and FDA-approved inhibitors of SARS-CoV-2 main protease 3CLpro
MA Alamri, M Tahir Ul Qamar, MU Mirza, R Bhadane, SM Alqahtani, ...
Journal of Biomolecular Structure and Dynamics 39 (13), 4936-4948, 2021
1072021
The cyclohexene ring system as a furanose mimic: synthesis and antiviral activity of both enantiomers of cyclohexenylguanine
J Wang, M Froeyen, C Hendrix, G Andrei, R Snoeck, E De Clercq, ...
Journal of medicinal chemistry 43 (4), 736-745, 2000
1072000
A Derivate of the Antibiotic Doxorubicin Is a Selective Inhibitor of Dengue and Yellow Fever Virus Replication In Vitro
SJF Kaptein, T De Burghgraeve, M Froeyen, B Pastorino, MMF Alen, ...
Antimicrobial agents and chemotherapy 54 (12), 5269-5280, 2010
982010
Rational Design of 5 ‘-Thiourea-Substituted α-Thymidine Analogues as Thymidine Monophosphate Kinase Inhibitors Capable of Inhibiting Mycobacterial Growth
I Van Daele, H Munier-Lehmann, M Froeyen, J Balzarini, ...
Journal of medicinal chemistry 50 (22), 5281-5292, 2007
952007
A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase
J Paeshuyse, P Leyssen, E Mabery, N Boddeker, R Vrancken, M Froeyen, ...
Journal of virology 80 (1), 149-160, 2006
852006
Marked depletion of glycosylation sites in HIV-1 gp120 under selection pressure by the mannose-specific plant lectins of Hippeastrum hybrid and Galanthus nivalis
J Balzarini, K Van Laethem, S Hatse, M Froeyen, E Van Damme, ...
Molecular pharmacology 67 (5), 1556-1565, 2005
822005
Reverse transcriptase incorporation of 1, 5-anhydrohexitol nucleotides
K Vastmans, M Froeyen, L Kerremans, S Pochet, P Herdewijn
Nucleic acids research 29 (15), 3154-3163, 2001
812001
The capsid binder vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replication
A Tijsma, D Franco, S Tucker, R Hilgenfeld, M Froeyen, P Leyssen, ...
Antimicrobial agents and chemotherapy 58 (11), 6990-6992, 2014
752014
3‘-C-Branched-Chain-Substituted Nucleosides and Nucleotides as Potent Inhibitors of Mycobacterium tuberculosis Thymidine Monophosphate Kinase
V Vanheusden, H Munier-Lehmann, M Froeyen, L Dugué, A Heyerick, ...
Journal of medicinal chemistry 46 (18), 3811-3821, 2003
752003
Understanding the mechanism of the broad-spectrum antiviral activity of favipiravir (T-705): key role of the F1 motif of the viral polymerase
R Abdelnabi, ATS Morais, P Leyssen, I Imbert, S Beaucourt, H Blanc, ...
Journal of virology 91 (12), 10.1128/jvi. 00487-17, 2017
722017
Difference in conformational diversity between nucleic acids with a six‐membered ‘sugar’unit and natural ‘furanose’nucleic acids
E Lescrinier, M Froeyen, P Herdewijn
Nucleic acids research 31 (12), 2975-2989, 2003
702003
Antiviral activity of broad-spectrum and enterovirus-specific inhibitors against clinical isolates of enterovirus D68
L Sun, A Meijer, M Froeyen, L Zhang, HJ Thibaut, J Baggen, S George, ...
Antimicrobial agents and chemotherapy 59 (12), 7782-7785, 2015
662015
Comparative study of the genetic barriers and pathways towards resistance of selective inhibitors of hepatitis C virus replication
L Delang, I Vliegen, M Froeyen, J Neyts
Antimicrobial agents and chemotherapy 55 (9), 4103-4113, 2011
662011
The system can't perform the operation now. Try again later.
Articles 1–20