| An oxygen-sensing diguanylate cyclase and phosphodiesterase couple for c-di-GMP control JR Tuckerman, G Gonzalez, EHS Sousa, X Wan, JA Saito, M Alam, ... Biochemistry 48 (41), 9764-9774, 2009 | 267 | 2009 |
| DosT and DevS are oxygen‐switched kinases in Mycobacterium tuberculosis EHS Sousa, JR Tuckerman, G Gonzalez, MA Gilles‐Gonzalez Protein Science 16 (8), 1708-1719, 2007 | 186 | 2007 |
| An inorganic iron complex that inhibits wild-type and an isoniazid-resistant mutant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis JS Oliveira, EHS Sousa, LA Basso, M Palaci, R Dietze, DS Santos, ... Chemical communications, 312-313, 2004 | 90 | 2004 |
| Slow-onset inhibition of 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis by an inorganic complex JS Oliveira, EHS de Sousa, ON de Souza, DS Santos, LA Basso Current pharmaceutical design 12 (19), 2409-2424, 2006 | 57 | 2006 |
| The potent anti-cancer activity of Dioclea lasiocarpa lectin ACS Gondim, I Romero-Canelon, EHS Sousa, CA Blindauer, JS Butler, ... Journal of Inorganic Biochemistry 175, 179-189, 2017 | 53 | 2017 |
| Thiol-activated HNO release from a ruthenium antiangiogenesis complex and HIF-1α inhibition for cancer therapy EH Silva Sousa, LA Ridnour, FS Gouveia Jr, CD Silva da Silva, DA Wink, ... ACS Chemical Biology 11 (7), 2057-2065, 2016 | 53 | 2016 |
| Isoniazid metal complex reactivity and insights for a novel anti-tuberculosis drug design EHS Sousa, LA Basso, DS Santos, ICN Diógenes, E Longhinotti, ... JBIC Journal of Biological Inorganic Chemistry 17, 275-283, 2012 | 52 | 2012 |
| Aryl-substituted ruthenium (II) complexes: a strategy for enhanced photocleavage and efficient DNA binding FD Abreu, TF Paulo, MH Gehlen, RA Ando, LGF Lopes, ACS Gondim, ... Inorganic Chemistry 56 (15), 9084-9096, 2017 | 51 | 2017 |
| Oxygen blocks the reaction of the FixL− FixJ complex with ATP but does not influence binding of FixJ or ATP to FixL EHS Sousa, G Gonzalez, MA Gilles-Gonzalez Biochemistry 44 (46), 15359-15365, 2005 | 45 | 2005 |
| Synthesis of bifunctional mesoporous silica spheres as potential adsorbent for ions in solution ECC Gomes, AF de Sousa, PHM Vasconcelos, DQ Melo, ICN Diógenes, ... Chemical engineering journal 214, 27-33, 2013 | 44 | 2013 |
| Mechanism and biological implications of the NO release of cis-[Ru (bpy) 2L (NO)] n+ complexes: A key role of physiological thiols FON Silva, MCL Cândido, AKM Holanda, ICN Diógenes, EHS Sousa, ... Journal of Inorganic Biochemistry 105 (5), 624-629, 2011 | 44 | 2011 |
| A memory of oxygen binding explains the dose response of the heme-based sensor FixL EHS Sousa, JR Tuckerman, G Gonzalez, MA Gilles-Gonzalez Biochemistry 46 (21), 6249-6257, 2007 | 42 | 2007 |
| A proximal arginine R206 participates in switching of the Bradyrhizobium japonicum FixL oxygen sensor MA Gilles-Gonzalez, AI Caceres, EHS Sousa, DR Tomchick, C Brautigam, ... Journal of molecular biology 360 (1), 80-89, 2006 | 39 | 2006 |
| Hell’s Gate globin I: an acid and thermostable bacterial hemoglobin resembling mammalian neuroglobin AH Teh, JA Saito, A Baharuddin, JR Tuckerman, JS Newhouse, M Kanbe, ... Febs Letters 585 (20), 3250-3258, 2011 | 38 | 2011 |
| The nitric oxide donor cis-[Ru (bpy) 2 (SO3) NO](PF6) increases gastric mucosa protection in mice–Involvement of the soluble guanylate cyclase/KATP pathway APM Santana, BM Tavares, LT Lucetti, FS Gouveia Jr, RA Ribeiro, ... Nitric Oxide 45, 35-42, 2015 | 37 | 2015 |
| The ruthenium NO donor,[Ru (bpy) 2 (NO) SO3](PF6), inhibits inflammatory pain: involvement of TRPV1 and cGMP/PKG/ATP-sensitive potassium channel signaling pathway L Staurengo-Ferrari, SS Mizokami, JJ Silva, FON da Silva, EHS Sousa, ... Pharmacology Biochemistry and Behavior 105, 157-165, 2013 | 37 | 2013 |
| Activity of IQG-607, a new orally active compound, in a murine model of Mycobacterium tuberculosis infection VS Rodrigues-Junior, A dos Santos Junior, AJ Dos Santos, CZ Schneider, ... International journal of antimicrobial agents 40 (2), 182-185, 2012 | 35 | 2012 |
| Electron transfer kinetics and mechanistic study of the thionicotinamide coordinated to the pentacyanoferrate (III)/(II) complexes: a model system for the in vitro activation … EHS Sousa, DL Pontes, ICN Diogenes, LGF Lopes, JS Oliveira, LA Basso, ... Journal of inorganic biochemistry 99 (2), 368-375, 2005 | 33 | 2005 |
| Oxygen‐Sensing Histidine‐Protein Kinases: Assays of Ligand Binding and Turnover of Response‐Regulator Substrates MA Gilles‐Gonzalez, G Gonzalez, EHS Sousa, J Tuckerman Methods in enzymology 437, 173-189, 2008 | 32 | 2008 |
| Nitro-imidazole-based ruthenium complexes with antioxidant and anti-inflammatory activities GL Sasahara, FSG Júnior, R de Oliveira Rodrigues, DS Zampieri, ... Journal of Inorganic Biochemistry 206, 111048, 2020 | 29 | 2020 |
Luiz Gonzaga de França LopesProfessor de Química da Universidade Federal do CearáVerified email at dqoi.ufc.br
