Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation ST Lim, XL Chen, Y Lim, DA Hanson, TT Vo, K Howerton, N Larocque, ... Molecular cell 29 (1), 9-22, 2008 | 550 | 2008 |
VEGF-induced vascular permeability is mediated by FAK XL Chen, JO Nam, C Jean, C Lawson, CT Walsh, E Goka, ST Lim, ... Developmental cell 22 (1), 146-157, 2012 | 386 | 2012 |
FAK promotes recruitment of talin to nascent adhesions to control cell motility C Lawson, ST Lim, S Uryu, XL Chen, DA Calderwood, DD Schlaepfer Journal of Cell Biology 196 (2), 223-232, 2012 | 298 | 2012 |
PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility Y Lim, ST Lim, A Tomar, M Gardel, JA Bernard-Trifilo, XL Chen, SA Uryu, ... The Journal of cell biology 180 (1), 187-203, 2008 | 272 | 2008 |
Syndecan-4 proteoglycan cytoplasmic domain and phosphatidylinositol 4, 5-bisphosphate coordinately regulate protein kinase C activity ES Oh, A Woods, ST Lim, AW Theibert, JR Couchman Journal of Biological Chemistry 273 (17), 10624-10629, 1998 | 245 | 1998 |
Understanding the roles of FAK in cancer: inhibitors, genetic models, and new insights H Yoon, JP Dehart, JM Murphy, STS Lim Journal of Histochemistry & Cytochemistry 63 (2), 114-128, 2015 | 227 | 2015 |
Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors SK Mitra, D Mikolon, JE Molina, DA Hsia, DA Hanson, A Chi, ST Lim, ... Oncogene 25 (44), 5969-5984, 2006 | 197 | 2006 |
A FAK-p120RasGAP-p190RhoGAP complex regulates polarity in migrating cells A Tomar, ST Lim, Y Lim, DD Schlaepfer Journal of cell science 122 (11), 1852-1862, 2009 | 185 | 2009 |
Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK SM Weis, ST Lim, KM Lutu-Fuga, LA Barnes, XL Chen, JR Göthert, ... The Journal of cell biology 181 (1), 43-50, 2008 | 182 | 2008 |
PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments I Tanjoni, C Walsh, S Uryu, A Tomar, JO Nam, A Mielgo, ST Lim, C Liang, ... Cancer biology & therapy 9 (10), 764-777, 2010 | 175 | 2010 |
FERM control of FAK function: implications for cancer therapy ST Lim, D Mikolon, D Stupack, D Schlaepfer Cell cycle 7 (15), 2306-2314, 2008 | 164 | 2008 |
Direct binding of syndecan-4 cytoplasmic domain to the catalytic domain of protein kinase Cα (PKCα) increases focal adhesion localization of PKCα ST Lim, RL Longley, JR Couchman, A Woods Journal of Biological Chemistry 278 (16), 13795-13802, 2003 | 163 | 2003 |
Intrinsic focal adhesion kinase activity controls orthotopic breast carcinoma metastasis via the regulation of urokinase plasminogen activator expression in a syngeneic tumor model SK Mitra, ST Lim, A Chi, DD Schlaepfer Oncogene 25 (32), 4429-4440, 2006 | 142 | 2006 |
Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression ST Lim, NLG Miller, XL Chen, I Tancioni, CT Walsh, C Lawson, S Uryu, ... Journal of Cell Biology 197 (7), 907-919, 2012 | 129 | 2012 |
Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation ST Lim, XL Chen, A Tomar, NLG Miller, J Yoo, DD Schlaepfer Journal of Biological Chemistry 285 (28), 21526-21536, 2010 | 127 | 2010 |
Targeting focal adhesion kinase in cancer cells and the tumor microenvironment JM Murphy, YAR Rodriguez, K Jeong, EYE Ahn, STS Lim Experimental & molecular medicine 52 (6), 877-886, 2020 | 125 | 2020 |
Distinct FAK-Src activation events promote α5β1 and α4β1 integrin-stimulated neuroblastoma cell motility L Wu, JA Bernard-Trifilo, Y Lim, ST Lim, SK Mitra, S Uryu, M Chen, ... Oncogene 27 (10), 1439-1448, 2008 | 117 | 2008 |
Nuclear FAK: a new mode of gene regulation from cellular adhesions STS Lim Molecules and cells 36 (1), 1-6, 2013 | 109 | 2013 |
Regulation of mitochondrial functions by protein phosphorylation and dephosphorylation S Lim, KR Smith, STS Lim, R Tian, J Lu, M Tan Cell & bioscience 6, 1-15, 2016 | 102 | 2016 |
De novo mutations in SON disrupt RNA splicing of genes essential for brain development and metabolism, causing an intellectual-disability syndrome JH Kim, DN Shinde, MRF Reijnders, NS Hauser, RL Belmonte, GR Wilson, ... The American Journal of Human Genetics 99 (3), 711-719, 2016 | 101 | 2016 |