| Prospective derivation of a living organoid biobank of colorectal cancer patients M Van de Wetering, HE Francies, JM Francis, G Bounova, F Iorio, A Pronk, ... Cell 161 (4), 933-945, 2015 | 2253 | 2015 |
| Sequence analysis of mutations and translocations across breast cancer subtypes S Banerji, K Cibulskis, C Rangel-Escareno, KK Brown, SL Carter, ... Nature 486 (7403), 405-409, 2012 | 1430 | 2012 |
| Chromothripsis from DNA damage in micronuclei CZ Zhang, A Spektor, H Cornils, JM Francis, EK Jackson, S Liu, ... Nature 522 (7555), 179-184, 2015 | 1199 | 2015 |
| Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma I Tirosh, AS Venteicher, C Hebert, LE Escalante, AP Patel, K Yizhak, ... Nature 539 (7628), 309-313, 2016 | 1084 | 2016 |
| Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors VA Adalsteinsson, G Ha, SS Freeman, AD Choudhury, DG Stover, ... Nature communications 8 (1), 1324, 2017 | 874 | 2017 |
| Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer JG Lohr, VA Adalsteinsson, K Cibulskis, AD Choudhury, M Rosenberg, ... Nature biotechnology 32 (5), 479-484, 2014 | 618 | 2014 |
| Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers X Zhang, PS Choi, JM Francis, M Imielinski, H Watanabe, AD Cherniack, ... Nature genetics 48 (2), 176-182, 2016 | 366 | 2016 |
| Somatic mutation of CDKN1B in small intestine neuroendocrine tumors JM Francis, A Kiezun, AH Ramos, S Serra, CS Pedamallu, ZR Qian, ... Nature genetics 45 (12), 1483-1486, 2013 | 358 | 2013 |
| EGFR Variant Heterogeneity in Glioblastoma Resolved through Single-Nucleus Sequencing JM Francis, CZ Zhang, CL Maire, J Jung, VE Manzo, VA Adalsteinsson, ... Cancer discovery 4 (8), 956-971, 2014 | 314 | 2014 |
| Deep learning using tumor HLA peptide mass spectrometry datasets improves neoantigen identification B Bulik-Sullivan, J Busby, CD Palmer, MJ Davis, T Murphy, A Clark, ... Nature biotechnology 37 (1), 55-63, 2019 | 289 | 2019 |
| Prognostic impact of novel molecular subtypes of small intestinal neuroendocrine tumor A Karpathakis, H Dibra, C Pipinikas, A Feber, T Morris, J Francis, D Oukrif, ... Clinical Cancer Research 22 (1), 250-258, 2016 | 196 | 2016 |
| Covalent histone modifications underlie the developmental regulation of insulin gene transcription in pancreatic β cells SK Chakrabarti, J Francis, SM Ziesmann, JC Garmey, RG Mirmira Journal of Biological Chemistry 278 (26), 23617-23623, 2003 | 188 | 2003 |
| SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas H Watanabe, Q Ma, S Peng, G Adelmant, D Swain, W Song, C Fox, ... The Journal of clinical investigation 124 (4), 1636-1645, 2014 | 187 | 2014 |
| Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1 W Lin, J Cao, J Liu, ML Beshiri, Y Fujiwara, J Francis, AD Cherniack, ... Proceedings of the National Academy of Sciences 108 (33), 13379-13386, 2011 | 164 | 2011 |
| Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of … T Iype, J Francis, JC Garmey, JC Schisler, R Nesher, GC Weir, TC Becker, ... Journal of Biological Chemistry 280 (17), 16798-16807, 2005 | 158 | 2005 |
| Small-molecule targeting of brachyury transcription factor addiction in chordoma T Sharifnia, MJ Wawer, T Chen, QY Huang, BA Weir, A Sizemore, ... Nature medicine 25 (2), 292-300, 2019 | 149 | 2019 |
| The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3′ mRNA processing factors O Rozenblatt-Rosen, T Nagaike, JM Francis, S Kaneko, KA Glatt, ... Proceedings of the National Academy of Sciences 106 (3), 755-760, 2009 | 149 | 2009 |
| Pdx-1 links histone H3-Lys-4 methylation to RNA polymerase II elongation during activation of insulin transcription J Francis, SK Chakrabarti, JC Garmey, RG Mirmira Journal of Biological Chemistry 280 (43), 36244-36253, 2005 | 125 | 2005 |
| Somatic superenhancer duplications and hotspot mutations lead to oncogenic activation of the KLF5 transcription factor X Zhang, PS Choi, JM Francis, GF Gao, JD Campbell, A Ramachandran, ... Cancer discovery 8 (1), 108-125, 2018 | 121 | 2018 |
| Cetuximab response of lung cancer–derived EGF receptor mutants is associated with asymmetric dimerization J Cho, L Chen, N Sangji, T Okabe, K Yonesaka, JM Francis, RJ Flavin, ... Cancer research 73 (22), 6770-6779, 2013 | 117 | 2013 |
