Jinfang Zhang
Jinfang Zhang
Instructor, Beth Israel Deaconess Medical Center, Harvard Medical School
Verified email at
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Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance
J Zhang, X Bu, H Wang, Y Zhu, Y Geng, NT Nihira, Y Tan, Y Ci, F Wu, ...
Nature 553 (7686), 91-95, 2018
The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer
WC Liang, WM Fu, CW Wong, Y Wang, WM Wang, GX Hu, L Zhang, ...
Oncotarget 6 (26), 22513, 2015
Translation of the circular RNA circβ-catenin promotes liver cancer cell growth through activation of the Wnt pathway
WC Liang, CW Wong, PP Liang, M Shi, Y Cao, ST Rao, SKW Tsui, ...
Genome biology 20, 1-12, 2019
PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex
P Liu, W Gan, YR Chin, K Ogura, J Guo, J Zhang, B Wang, J Blenis, ...
Cancer discovery 5 (11), 1194-1209, 2015
MiRNA-20a promotes osteogenic differentiation of human mesenchymal stem cells by co-regulating BMP signaling
J Zhang, W Fu, M He, W Xie, Q Lv, G Wan, G Li, H Wang, G Lu, X Hu, ...
RNA biology 8 (5), 829-838, 2011
Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4
X Dai, W Gan, X Li, S Wang, W Zhang, L Huang, S Liu, Q Zhong, J Guo, ...
Nature medicine 23 (9), 1063-1071, 2017
H19 activates Wnt signaling and promotes osteoblast differentiation by functioning as a competing endogenous RNA
WC Liang, WM Fu, YB Wang, YX Sun, LL Xu, CW Wong, KM Chan, G Li, ...
Scientific reports 6 (1), 20121, 2016
Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway
YR Lee, M Chen, JD Lee, J Zhang, SY Lin, TM Fu, H Chen, T Ishikawa, ...
Science 364 (6441), eaau0159, 2019
Targeting Cdc20 as a novel cancer therapeutic strategy
L Wang, J Zhang, L Wan, X Zhou, Z Wang, W Wei
Pharmacology & therapeutics 151, 141-151, 2015
MiR-637 maintains the balance between adipocytes and osteoblasts by directly targeting Osterix
J Zhang, W Fu, M He, H Wang, W Wang, S Yu, XW Bian, J Zhou, MCM Lin, ...
Molecular biology of the cell 22 (21), 3955-3961, 2011
SPOP promotes ubiquitination and degradation of the ERG oncoprotein to suppress prostate cancer progression
W Gan, X Dai, A Lunardi, Z Li, H Inuzuka, P Liu, S Varmeh, J Zhang, ...
Molecular cell 59 (6), 917-930, 2015
Biochemical aspects of PD-L1 regulation in cancer immunotherapy
J Zhang, F Dang, J Ren, W Wei
Trends in biochemical sciences 43 (12), 1014-1032, 2018
pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner
WW d. Guo J, Chakraborty AA, Liu P, Gan W, Zheng X, Inuzuka H, Wang B, Zhang ...
Science 353 (6302), 929-32, 2016
Hotair mediates hepatocarcinogenesis through suppressing miRNA-218 expression and activating P14 and P16 signaling
WM Fu, X Zhu, WM Wang, YF Lu, BG Hu, H Wang, WC Liang, SS Wang, ...
Journal of hepatology 63 (4), 886-895, 2015
Flavonoids of Herba Epimedii regulate osteogenesis of human mesenchymal stem cells through BMP and Wnt/β-catenin signaling pathway
J Zhang, G Li, C Chan, C Meng, MC Lin, Y Chen, M He, P Leung, H Kung
Molecular and Cellular Endocrinology 314 (1), 70-74, 2010
Phosphorylation of EZH2 by AMPK suppresses PRC2 methyltransferase activity and oncogenic function
L Wan, K Xu, Y Wei, J Zhang, T Han, C Fry, Z Zhang, YV Wang, L Huang, ...
Molecular cell 69 (2), 279-291. e5, 2018
TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling
B Wang, Z Jie, D Joo, A Ordureau, P Liu, W Gan, J Guo, J Zhang, BJ North, ...
Nature 545 (7654), 365-369, 2017
Long noncoding RNA Hotair mediated angiogenesis in nasopharyngeal carcinoma by direct and indirect signaling pathways
W Fu, Y Lu, B Hu, W Liang, X Zhu, G Li, J Zhang
Oncotarget 7 (4), 4712, 2016
Primate‐specific microRNA‐637 inhibits tumorigenesis in hepatocellular carcinoma by disrupting signal transducer and activator of transcription 3 signaling
J Zhang, M He, W Fu, H Wang, L Chen, X Zhu, Y Chen, D Xie, P Lai, ...
Hepatology 54 (6), 2137-2148, 2011
LncRNA-NEF antagonized epithelial to mesenchymal transition and cancer metastasis via cis-regulating FOXA2 and inactivating Wnt/β-catenin signaling
WC Liang, JL Ren, CW Wong, SO Chan, MMY Waye, WM Fu, JF Zhang
Oncogene 37 (11), 1445-1456, 2018
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