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M. Lienhard Schmitz
M. Lienhard Schmitz
Professor of Biochemistry, University of Giessen
Verified email at biochemie.med.uni-giessen.de - Homepage
Title
Cited by
Cited by
Year
The p65 subunit is responsible for the strong transcription activating potential of NF‐kappa B.
ML Schmitz, PA Baeuerle
The EMBO journal 10 (12), 3805-3817, 1991
10451991
p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-κB p65 transactivation mediated by tumor necrosis factor
WV Berghe, S Plaisance, E Boone, K De Bosscher, ML Schmitz, W Fiers, ...
Journal of Biological Chemistry 273 (6), 3285-3290, 1998
8331998
Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2
TG Hofmann, A Möller, H Sirma, H Zentgraf, Y Taya, W Dröge, H Will, ...
Nature cell biology 4 (1), 1-10, 2002
7362002
The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-κB by targeting the IκB kinase complex
SP Hehner, TG Hofmann, W Dröge, ML Schmitz
The Journal of Immunology 163 (10), 5617-5623, 1999
5321999
Sesquiterpene lactones specifically inhibit activation of NF-κB by preventing the degradation of IκB-α and IκB-β
SP Hehner, M Heinrich, PM Bork, M Vogt, F Ratter, V Lehmann, ...
Journal of Biological Chemistry 273 (3), 1288-1297, 1998
4901998
Constitutive and interleukin-1-inducible phosphorylation of p65 NF-κB at serine 536 is mediated by multiple protein kinases including IκB kinase (IKK)-α, IKKβ, IKKϵ, TRAF …
H Buss, A Dörrie, ML Schmitz, E Hoffmann, K Resch, M Kracht
Journal of Biological Chemistry 279 (53), 55633-55643, 2004
4822004
Glucocorticoid-mediated repression of nuclear factor-κBdependent transcription involves direct interference with transactivation
K De Bosscher, ML Schmitz, W Vanden Berghe, S Plaisance, W Fiers, ...
Proceedings of the National Academy of Sciences 94 (25), 13504-13509, 1997
4611997
Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF‐κB
PM Bork, ML Schmitz, M Kuhnt, C Escher, M Heinrich
FEBS letters 402 (1), 85-90, 1997
4351997
The dual function cytokine IL-33 interacts with the transcription factor NF-κB to dampen NF-κB–stimulated gene transcription
S Ali, A Mohs, M Thomas, J Klare, R Ross, ML Schmitz, MU Martin
The Journal of Immunology 187 (4), 1609-1616, 2011
4172011
Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-κB
A Dumont, SP Hehner, TG Hofmann, M Ueffing, W DroÈge, ML Schmitz
Oncogene 18 (3), 747-757, 1999
4171999
NF‐κB: a multifaceted transcription factor regulated at several levels
ML Schmitz, I Mattioli, H Buss, M Kracht
Chembiochem 5 (10), 1348-1358, 2004
3592004
The pro‐or anti‐apoptotic function of NF‐κB is determined by the nature of the apoptotic stimulus
B Kaltschmidt, C Kaltschmidt, TG Hofmann, SP Hehner, W Dröge, ...
European journal of biochemistry 267 (12), 3828-3835, 2000
3502000
Phosphorylation of serine 468 by GSK-3β negatively regulates basal p65 NF-κB activity
H Buss, A Dorrie, ML Schmitz, R Frank, M Livingstone, K Resch, M Kracht
Journal of Biological Chemistry 279 (48), 49571-49574, 2004
3282004
IκB-independent control of NF-κB activity by modulatory phosphorylations
ML Schmitz, S Bacher, M Kracht
Trends in biochemical sciences 26 (3), 186-190, 2001
3252001
Activation of transcription factor NF-κB and p38 mitogen-activated protein kinase is mediated by distinct and separate stress effector pathways
S Wesselborg, MKA Bauer, M Vogt, ML Schmitz, K Schulze-Osthoff
Journal of Biological Chemistry 272 (19), 12422-12429, 1997
2991997
Transient and selective NF-κB p65 serine 536 phosphorylation induced by T cell costimulation is mediated by IκB kinase β and controls the kinetics of p65 nuclear import
I Mattioli, A Sebald, C Bucher, RP Charles, H Nakano, M Kracht, ...
The Journal of Immunology 172 (10), 6336-6344, 2004
2842004
Sex reversal by loss of the C–terminal transactivation domain of human SOX9
P Südbeck, ML Schmitz, PA Baeuerle, G Scherer
Nature genetics 13 (2), 230-232, 1996
2651996
SUMO5, a novel poly-SUMO isoform, regulates PML nuclear bodies
YC Liang, CC Lee, YL Yao, CC Lai, ML Schmitz, WM Yang
Scientific reports 6 (1), 26509, 2016
2262016
Mutational Analysis of the SOX9 Gene in Campomelic Dysplasia and Autosomal Sex Reversal: Lack of Genotype/Phenotype Correlations
J Meyer, P Südbeck, M Held, T Wagner, ML Schmitz, F Dagna Bricarelli, ...
Human molecular genetics 6 (1), 91-98, 1997
2181997
Interaction of the COOH-terminal transactivation domain of p65 NF-κB with TATA-binding protein, transcription factor IIB, and coactivators
ML Schmitz, G Stelzer, H Altmann, M Meisterernst, PA Baeuerle
Journal of Biological Chemistry 270 (13), 7219-7226, 1995
2081995
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