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Ashraf N. Abdalla
Ashraf N. Abdalla
Associate Professor of Pharmacology (Ph.D.), College of Pharmacy, Umm Alqura University, Saudi
Verified email at uqu.edu.sa - Homepage
Title
Cited by
Cited by
Year
A comprehensive overview of globally approved JAK inhibitors
AM Shawky, FA Almalki, AN Abdalla, AH Abdelazeem, AM Gouda
Pharmaceutics 14 (5), 1001, 2022
942022
Phytochemical, cytotoxic, and antimicrobial evaluation of the fruits of miswak plant, Salvadora persica L.
M Al Bratty, HA Makeen, HA Alhazmi, SM Syame, AN Abdalla, ...
Journal of Chemistry 2020, 1-11, 2020
702020
Proapoptotic Activity of Achillea membranacea Essential Oil and Its Major Constituent 1,8-Cineole against A2780 Ovarian Cancer Cells
AN Abdalla, U Shaheen, QMA Abdallah, G Flamini, MM Bkhaitan, ...
Molecules 25 (7), 1582, 2020
502020
Antitumor activity of pyrrolizines and their Cu (II) complexes: Design, synthesis and cytotoxic screening with potential apoptosis-inducing activity
AM Gouda, HA El-Ghamry, TM Bawazeer, TA Farghaly, AN Abdalla, ...
European journal of medicinal chemistry 145, 350-359, 2018
502018
Optimization of pyrrolizine-based Schiff bases with 4-thiazolidinone motif: Design, synthesis and investigation of cytotoxicity and anti-inflammatory potency
AMG Ahmed M. Shawky, Mohammed A.S. Abourehab, Ashraf N. Abdalla
European journal of medicinal chemistry, 2019
49*2019
Synthesis, cytotoxic evaluation, and molecular docking studies of novel quinazoline derivatives with benzenesulfonamide and anilide tails: Dual inhibitors of EGFR/HER2
ASEA Hamad M.Alkahtani, Ashraf N.Abdalla, Ahmad J.Obaidullah, Mohammed M ...
Bioorganic chemistry 2019, 2019
48*2019
Synthesis, anticancer, apoptosis-inducing activities and EGFR and VEGFR2 assay mechanistic studies of 5, 5-diphenylimidazolidine-2, 4-dione derivatives: Molecular docking studies
HM Alkahtani, MM Alanazi, FS Aleanizy, FY Alqahtani, A Alhoshani, ...
Saudi Pharmaceutical Journal 27 (5), 682-693, 2019
422019
Triterpenoidal saponins from the fruits of Gleditsia caspica with proapoptotic properties
U Shaheen, EA Ragab, AN Abdalla, A Bader
Phytochemistry 145, 168-178, 2018
422018
A series of isatin-hydrazones with cytotoxic activity and CDK2 kinase inhibitory activity: a potential type II ATP competitive inhibitor
HS Al-Salem, M Arifuzzaman, HM Alkahtani, AN Abdalla, IS Issa, ...
Molecules 25 (19), 4400, 2020
342020
Pharmacophore-based virtual screening, synthesis, biological evaluation, and molecular docking study of novel pyrrolizines bearing urea/thiourea moieties with potential …
AM Shawky, NA Ibrahim, MAS Abourehab, AN Abdalla, AM Gouda
Journal of enzyme inhibition and medicinal chemistry 36 (1), 15-33, 2021
272021
Ethyl benzoate bearing pyrrolizine/indolizine moieties: Design, synthesis and biological evaluation of anti-inflammatory and cytotoxic activities
KM Attalah, AN Abdalla, A Aslam, M Ahmed, MAS Abourehab, NA ElSawy, ...
Bioorganic chemistry 94, 103371, 2020
272020
One-pot synthesis of novel poly-substituted 3-cyanopyridines: Molecular docking, antimicrobial, cytotoxicity, and DFT/TD-DFT studies
IM Abdellah, MR Eletmany, AA Abdelhamid, HS Alghamdi, AN Abdalla, ...
Journal of Molecular Structure 1289, 135864, 2023
262023
Tamoxifen and the PI3K inhibitor: LY294002 synergistically induce apoptosis and cell cycle arrest in breast cancer MCF-7 cells
ME Abdallah, MZ El-Readi, MA Althubiti, RA Almaimani, AM Ismail, S Idris, ...
Molecules 25 (15), 3355, 2020
252020
Pyrrolizines: design, synthesis, anticancer evaluation and investigation of the potential mechanism of action
AM Gouda, AH Abdelazeem, HA Omar, AN Abdalla, MAS Abourehab, ...
Bioorganic & Medicinal Chemistry 25 (20), 5637-5651, 2017
242017
Synthesis, biological evaluation and molecular docking study of benzimidazole derivatives as α-glucosidase inhibitors and anti-diabetes candidates
S Hayat, H Ullah, F Rahim, I Ullah, M Taha, N Iqbal, F Khan, MS Khan, ...
Journal of Molecular Structure 1276, 134774, 2023
232023
Identification of novel inhibitors for SARS-CoV-2 as therapeutic options using machine learning-based virtual screening, molecular docking and MD simulation
A Samad, A Ajmal, A Mahmood, B Khurshid, P Li, SM Jan, AU Rehman, ...
Frontiers in Molecular Biosciences 10, 1060076, 2023
212023
Discovery of new pyrimidopyrrolizine/indolizine-based derivatives as P-glycoprotein inhibitors: Design, synthesis, cytotoxicity, and MDR reversal activities
AM Shawky, AN Abdalla, NA Ibrahim, MAS Abourehab, AM Gouda
European Journal of Medicinal Chemistry 218, 113403, 2021
212021
Phytochemical Screening and Cytotoxic Properties of Ethanolic Extract of Young and Mature Khat Leaves
6 Rashad Alsanosy,1,2 Hassan A. Alhazmi ,1,3 Shahnaz Sultana,4 Ashraf N ...
Journal of chemistry 7897435, 2020
21*2020
Structural-based design, synthesis, and antitumor activity of novel alloxazine analogues with potential selective kinase inhibition
WH Malki, AM Gouda, HEA Ali, R Al-Rousan, D Samaha, AN Abdalla, ...
European Journal of Medicinal Chemistry 152, 31-52, 2018
212018
Reprofiling of full‐length phosphonated carbocyclic 2′‐oxa‐3′‐aza‐nucleosides toward antiproliferative agents: Synthesis, antiproliferative activity, and molecular docking study
MM Bkhaitan, AZ Mirza, AN Abdalla, H Shamshad, Z Ul‐Haq, M Alarjah, ...
Chemical Biology & Drug Design 90 (5), 679-689, 2017
212017
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