Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility International Multiple Sclerosis Genetics Consortium*†, ANZgene, ... Science 365 (6460), eaav7188, 2019 | 1031 | 2019 |
Clinical course, therapeutic responses and outcomes in relapsing MOG antibody-associated demyelination S Ramanathan, S Mohammad, E Tantsis, TK Nguyen, V Merheb, ... Journal of Neurology, Neurosurgery & Psychiatry 89 (2), 127-137, 2018 | 556 | 2018 |
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease S Mostafavi, C Gaiteri, SE Sullivan, CC White, S Tasaki, J Xu, M Taga, ... Nature neuroscience 21 (6), 811-819, 2018 | 442 | 2018 |
A transcriptomic atlas of aged human microglia M Olah, E Patrick, AC Villani, J Xu, CC White, KJ Ryan, P Piehowski, ... Nature communications 9 (1), 539, 2018 | 440 | 2018 |
An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome B Ng, CC White, HU Klein, SK Sieberts, C McCabe, E Patrick, J Xu, L Yu, ... Nature neuroscience 20 (10), 1418-1426, 2017 | 425 | 2017 |
Mass cytometry imaging for the study of human diseases—applications and data analysis strategies H Baharlou, NP Canete, AL Cunningham, AN Harman, E Patrick Frontiers in immunology 10, 2657, 2019 | 172 | 2019 |
Impaired Akt phosphorylation in insulin-resistant human muscle is accompanied by selective and heterogeneous downstream defects. KT Tonks, Y Ng, S Miller, AC Coster, D Samocha-Bonet, TJ Iseli, A Xu, ... Diabetologia, 2013 | 124 | 2013 |
The Multiple Sclerosis Genomic Map: Role of peripheral immune cells and resident microglia in susceptibility International Multiple Sclerosis Genetics Consortium, NA Patsopoulos, ... BioRxiv, 143933, 2017 | 99 | 2017 |
Deconvolving the contributions of cell-type heterogeneity on cortical gene expression E Patrick, M Taga, A Ergun, B Ng, W Casazza, M Cimpean, C Yung, ... PLOS Computational Biology 16 (8), e1008120, 2020 | 98 | 2020 |
Identification of HIV transmitting CD11c+ human epidermal dendritic cells KM Bertram, RA Botting, H Baharlou, JW Rhodes, H Rana, JD Graham, ... Nature communications 10 (1), 2759, 2019 | 88 | 2019 |
Characterization of the human myelin oligodendrocyte glycoprotein antibody response in demyelination F Tea, JA Lopez, S Ramanathan, V Merheb, FXZ Lee, A Zou, D Pilli, ... Acta Neuropathologica Communications 7, 1-22, 2019 | 83 | 2019 |
Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer’s disease E Patrick, S Rajagopal, HKA Wong, C McCabe, J Xu, A Tang, ... Molecular Neurodegeneration 12 (1), 51, 2017 | 80 | 2017 |
MicroRNA and mRNA expression profiling in metastatic melanoma reveal associations with BRAF mutation and patient prognosis V Tembe, SJ Schramm, MS Stark, E Patrick, V Jayaswal, YH Tang, ... Pigment cell & melanoma research 28 (3), 254-266, 2015 | 66 | 2015 |
Investigating higher-order interactions in single-cell data with scHOT S Ghazanfar, Y Lin, X Su, DM Lin, E Patrick, ZG Han, JC Marioni, ... Nature methods 17 (8), 799-806, 2020 | 64 | 2020 |
Evaluating stably expressed genes in single cells Y Lin, S Ghazanfar, D Strbenac, A Wang, E Patrick, DM Lin, T Speed, ... GigaScience 8 (9), giz106, 2019 | 60 | 2019 |
Defining early changes in Alzheimer’s disease from RNA sequencing of brain regions differentially affected by pathology B Guennewig, J Lim, L Marshall, AN McCorkindale, PJ Paasila, E Patrick, ... Scientific Reports 11 (1), 4865, 2021 | 55 | 2021 |
Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain D Felsky, E Patrick, JA Schneider, S Mostafavi, C Gaiteri, N Patsopoulos, ... Molecular neurodegeneration 13, 1-10, 2018 | 45 | 2018 |
The acute phase protein lactoferrin is a key feature of Alzheimer’s disease and predictor of Aβ burden through induction of APP amyloidogenic processing A Tsatsanis, AN McCorkindale, BX Wong, E Patrick, TM Ryan, RW Evans, ... Molecular psychiatry 26 (10), 5516-5531, 2021 | 41 | 2021 |
PGRMC1 phosphorylation affects cell shape, motility, glycolysis, mitochondrial form and function, and tumor growth BM Thejer, PP Adhikary, A Kaur, SL Teakel, A Van Oosterum, I Seth, ... BMC molecular and cell biology 21, 1-24, 2020 | 40 | 2020 |
Brief normothermic machine perfusion rejuvenates discarded human kidneys AM Hameed, DB Lu, E Patrick, BO Xu, M Hu, YV Chew, K Keung, CH P’ng, ... Transplantation Direct 5 (11), e502, 2019 | 39 | 2019 |