Sophie Dutheil
Sophie Dutheil
Senior Scientist at Intra-Cellular Therapies, Inc.
Verified email at intracellulartherapies.com
Title
Cited by
Cited by
Year
Psychological stress activates the inflammasome via release of adenosine triphosphate and stimulation of the purinergic type 2X7 receptor
M Iwata, KT Ota, XY Li, F Sakaue, N Li, S Dutheil, M Banasr, V Duric, ...
Biological psychiatry 80 (1), 12-22, 2016
1802016
REDD1 is essential for stress-induced synaptic loss and depressive behavior
KT Ota, RJ Liu, B Voleti, JG Maldonado-Aviles, V Duric, M Iwata, S Dutheil, ...
Nature medicine 20 (5), 531-535, 2014
1642014
High-fat diet induced anxiety and anhedonia: impact on brain homeostasis and inflammation
S Dutheil, KT Ota, ES Wohleb, K Rasmussen, RS Duman
Neuropsychopharmacology 41 (7), 1874-1887, 2016
1292016
Rapid antidepressant actions of scopolamine: Role of medial prefrontal cortex and M1-subtype muscarinic acetylcholine receptors
A Navarria, ES Wohleb, B Voleti, KT Ota, S Dutheil, AE Lepack, JM Dwyer, ...
Neurobiology of disease 82, 254-261, 2015
692015
Tell me your vestibular deficit, and I’ll tell you how you’ll compensate
M Lacour, S Dutheil, B Tighilet, C Lopez, L Borel
Annals of the New York Academy of Sciences 1164 (1), 268-278, 2009
622009
Neurogenesis and astrogenesis contribution to recovery of vestibular functions in the adult cat following unilateral vestibular neurectomy: cellular and behavioral evidence
S Dutheil, JM Brezun, J Leonard, M Lacour, B Tighilet
Neuroscience 164 (4), 1444-1456, 2009
602009
Ketamine strengthens CRF-activated amygdala inputs to basal dendrites in mPFC layer V pyramidal cells in the prelimbic but not infralimbic subregion, a key suppressor of stress …
RJ Liu, KT Ota, S Dutheil, RS Duman, GK Aghajanian
Neuropsychopharmacology 40 (9), 2066-2075, 2015
382015
Neurogenic potential of the vestibular nuclei and behavioural recovery time course in the adult cat are governed by the nature of the vestibular damage
S Dutheil, M Lacour, B Tighilet
PLoS One 6 (8), e22262, 2011
312011
Role of neuronal VEGF signaling in the prefrontal cortex in the rapid antidepressant effects of ketamine
S Deyama, E Bang, ES Wohleb, XY Li, T Kato, DM Gerhard, S Dutheil, ...
American Journal of Psychiatry 176 (5), 388-400, 2019
302019
GABAA Receptor agonist and antagonist alter vestibular compensation and different steps of reactive neurogenesis in deafferented vestibular nuclei of adult cats
S Dutheil, G Escoffier, A Gharbi, I Watabe, B Tighilet
Journal of Neuroscience 33 (39), 15555-15566, 2013
262013
BDNF signaling promotes vestibular compensation by increasing neurogenesis and remodeling the expression of potassium-chloride cotransporter KCC2 and GABAA receptor in the …
S Dutheil, I Watabe, K Sadlaoud, A Tonetto, B Tighilet
Journal of Neuroscience 36 (23), 6199-6212, 2016
172016
Discovering a new functional neurogenic zone: the vestibular nuclei of the brainstem
S Dutheil, M Lacour, B Tighilet
Medecine sciences: M/S 27 (6-7), 605-613, 2011
82011
Reactive Neurogenesis and Down-Regulation of the Potassium-Chloride Cotransporter KCC2 in the Cochlear Nuclei after Cochlear Deafferentation.
NAJ Tighilet B, Dutheil S, Siponen MI
Front Pharmacol 7 (281), 2016
52016
[P4–587]: SUPPRESSION OF CNS INFLAMMATION BY PHOSPHODIESTERASE‐1 (PDE1) INHIBITORS: TOWARD NEW TREATMENTS FOR NEURODEGENERATIVE DISEASES
GL Snyder, S Dutheil, JL O'Brien, S Cruz, Y Tian, JP Hendrick, ...
Alzheimer's & Dementia 13 (7S_Part_32), P1579-P1579, 2017
32017
S81. Unique Pharmacology and Clinical Evidence Supporting the Antidepressant Therapeutic Potential of Lumateperone
G Snyder, R Davis, S Dutheil, J Hendrick, L Zhang, L Wennogle, A Satlin, ...
Biological Psychiatry 83 (9), S378, 2018
12018
Lumateperone Uniquely Enhances Glutamatergic Neurotransmission Through Activation of Both NMDA and AMPA Channels via a Dopamine D1 Receptor-Dependent Mechanism: Implications …
T Svensson, S Dutheil, J Hendrick, L Zhang, L Wennogle, C O'Gorman, ...
NEUROPSYCHOPHARMACOLOGY 43, S160-S161, 2017
12017
Sodium Nitroprusside Enhances the Antipsychotic-Like Effect of Lumateperone in the Conditioned Avoidance Response Test
J Titulaer, O Radhe, L Almer, O Yakimenko, E Berggren, ...
NEUROPSYCHOPHARMACOLOGY 44 (SUPPL 1), 333-334, 2019
2019
ITI-214, a Potent and Selective PDE 1 Inhibitor: A New Approach to the Treatment of Neurodegenerative Diseases, Including Parkinson's Disease
JJ O'Brien, S Dutheil, S Cruz, LP Wennogle, C O'Gorman, P Li, RE Davis, ...
NEUROPSYCHOPHARMACOLOGY 42, S405-S406, 2017
2017
Activation of NMDA and AMPA receptors by lumateperone (ITI-007): implications for antidepressant activity
G Snyder, S Mates, K Vanover, S Dutheil, J Hendrick, L Wennogle, ...
BIPOLAR DISORDERS 19, 127-127, 2017
2017
Role of VEGF signaling in the medial prefrontal cortex in the rapid antidepressant actions of ketamine
S Deyama, E Bang, ES Wohleb, XY Li, T Kato, DM Gerhard, S Dutheil, ...
JOURNAL OF PHARMACOLOGICAL SCIENCES 133 (3), S84-S84, 2017
2017
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