Brendan Wren
Brendan Wren
Professor of Pathogen Molecular Biology
Verified email at lshtm.ac.uk - Homepage
TitleCited byYear
The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences
J Parkhill, BW Wren, K Mungall, JM Ketley, C Churcher, D Basham, ...
Nature 403 (6770), 665, 2000
19962000
Genome sequence of Yersinia pestis, the causative agent of plague
J Parkhill, BW Wren, NR Thomson, RW Titball, MTG Holden, MB Prentice, ...
Nature 413 (6855), 523, 2001
13222001
The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome
M Sebaihia, BW Wren, P Mullany, NF Fairweather, N Minton, R Stabler, ...
Nature genetics 38 (7), 779, 2006
7752006
N-linked glycosylation in Campylobacter jejuni and its functional transfer into E. coli
M Wacker, D Linton, PG Hitchen, M Nita-Lazar, SM Haslam, SJ North, ...
Science 298 (5599), 1790-1793, 2002
7312002
Emergence and global spread of epidemic healthcare-associated Clostridium difficile
M He, F Miyajima, P Roberts, L Ellison, DJ Pickard, MJ Martin, TR Connor, ...
Nature genetics 45 (1), 109, 2013
5452013
The complete genome sequence of Francisella tularensis, the causative agent of tularemia
P Larsson, PCF Oyston, P Chain, MC Chu, M Duffield, HH Fuxelius, ...
Nature genetics 37 (2), 153, 2005
4712005
The HtrA family of serine proteases
MJ Pallen, BW Wren
Molecular microbiology 26 (2), 209-221, 1997
4441997
Protein glycosylation in bacterial mucosal pathogens
CM Szymanski, BW Wren
Nature Reviews Microbiology 3 (3), 225, 2005
4402005
Bacterial pathogenomics
MJ Pallen, BW Wren
Nature 449 (7164), 835, 2007
3862007
Whole genome comparison of Campylobacter jejuni human isolates using a low-cost microarray reveals extensive genetic diversity
N Dorrell, JA Mangan, KG Laing, J Hinds, D Linton, H Al-Ghusein, ...
Genome research 11 (10), 1706-1715, 2001
3752001
The yersiniae—a model genus to study the rapid evolution of bacterial pathogens
BW Wren
Nature Reviews Microbiology 1 (1), 55, 2003
3632003
Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium
RA Stabler, M He, L Dawson, M Martin, E Valiente, C Corton, TD Lawley, ...
Genome biology 10 (9), R102, 2009
3522009
Evolutionary dynamics of Clostridium difficile over short and long time scales
M He, M Sebaihia, TD Lawley, RA Stabler, LF Dawson, MJ Martin, KE Holt, ...
Proceedings of the National Academy of Sciences 107 (16), 7527-7532, 2010
3272010
Antibiotic treatment of Clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts
TD Lawley, S Clare, AW Walker, D Goulding, RA Stabler, N Croucher, ...
Infection and immunity 77 (9), 3661-3669, 2009
2882009
Genetic and biochemical evidence of a Campylobacter jejuni capsular polysaccharide that accounts for Penner serotype specificity
AV Karlyshev, D Linton, NA Gregson, AJ Lastovica, BW Wren
Molecular microbiology 35 (3), 529-541, 2000
2872000
Neutrophil granulocytes–Trojan horses for Leishmania major and other intracellular microbes?
T Laskay, G Van Zandbergen, W Solbach
Trends in microbiology 11 (5), 210-214, 2003
2572003
Biofilm formation in Campylobacter jejuni
GWP Joshua, C Guthrie-Irons, AV Karlyshev, BW Wren
Microbiology 152 (2), 387-396, 2006
2382006
The Clostridium difficile spo0A gene is a persistence and transmission factor
LJ Deakin, S Clare, RP Fagan, LF Dawson, DJ Pickard, MR West, ...
Infection and immunity 80 (8), 2704-2711, 2012
2302012
The response regulator PhoP is important for survival under conditions of macrophage-induced stress and virulence in Yersinia pestis
PCF Oyston, N Dorrell, K Williams, SR Li, M Green, RW Titball, BW Wren
Infection and immunity 68 (6), 3419-3425, 2000
2292000
The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081
NR Thomson, S Howard, BW Wren, MTG Holden, L Crossman, GL Challis, ...
PLoS genetics 2 (12), e206, 2006
2262006
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