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Husain Yar Khan
Husain Yar Khan
Karmanos Cancer Institute, Wayne State University School of Medicine
Verified email at karmanos.org
Title
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Cited by
Year
A prooxidant mechanism for the anticancer and chemopreventive properties of plant polyphenols
H Yar Khan, H Zubair, M Fahad Ullah, A Ahmad, S Mumtaz Hadi
Current Drug Targets 13 (14), 1738-1749, 2012
1452012
Effect of vitamins C and E on antioxidant status of breast‐cancer patients undergoing chemotherapy
N Suhail, N Bilal, HY Khan, S Hasan, S Sharma, F Khan, T Mansoor, ...
Journal of clinical pharmacy and therapeutics 37 (1), 22-26, 2012
1232012
Soy isoflavone genistein induces cell death in breast cancer cells through mobilization of endogenous copper ions and generation of reactive oxygen species
MF Ullah, A Ahmad, H Zubair, HY Khan, Z Wang, FH Sarkar, SM Hadi
Molecular nutrition & food research 55 (4), 553-559, 2011
1212011
Redox cycling of endogenous copper by thymoquinone leads to ROS-mediated DNA breakage and consequent cell death: putative anticancer mechanism of antioxidants
H Zubair, HY Khan, A Sohail, S Azim, MF Ullah, A Ahmad, FH Sarkar, ...
Cell death & disease 4 (6), e660-e660, 2013
1162013
Plant polyphenol induced cell death in human cancer cells involves mobilization of intracellular copper ions and reactive oxygen species generation: a mechanism for cancer …
HY Khan, H Zubair, M Faisal, MF Ullah, M Farhan, FH Sarkar, A Ahmad, ...
Molecular nutrition & food research 58 (3), 437-446, 2014
972014
Resveratrol mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage: a putative mechanism for chemoprevention of cancer
SM Hadi, MF Ullah, AS Azmi, A Ahmad, U Shamim, H Zubair, HY Khan
Pharmaceutical research 27 (6), 979-988, 2010
952010
The antioxidant ascorbic acid mobilizes nuclear copper leading to a prooxidant breakage of cellular DNA: implications for chemotherapeutic action against cancer
MF Ullah, HY Khan, H Zubair, U Shamim, SM Hadi
Cancer chemotherapy and pharmacology 67 (1), 103-110, 2011
752011
Cancer therapy by catechins involves redox cycling of copper ions and generation of reactive oxygen species
M Farhan, HY Khan, M Oves, A Al-Harrasi, N Rehmani, H Arif, SM Hadi, ...
Toxins 8 (2), 37, 2016
722016
Oral administration of copper to rats leads to increased lymphocyte cellular DNA degradation by dietary polyphenols: implications for a cancer preventive mechanism
HY Khan, H Zubair, MF Ullah, A Ahmad, SM Hadi
Biometals 24 (6), 1169-1178, 2011
532011
The prooxidant action of dietary antioxidants leading to cellular DNA breakage and anticancer effects: implications for chemotherapeutic action against cancer
MF Ullah, A Ahmad, HY Khan, H Zubair, FH Sarkar, SM Hadi
Cell biochemistry and biophysics 67 (2), 431-438, 2013
452013
Chemistry and bioactivity of boswellic acids and other terpenoids of the genus Boswellia
A Al-Harrasi, H Hussain, R Csuk, HY Khan
Elsevier, 2018
292018
Preclinical Assessment with Clinical Validation of Selinexor with Gemcitabine and Nab-Paclitaxel for the Treatment of Pancreatic Ductal AdenocarcinomaExportin 1 for Pancreatic …
AS Azmi, HY Khan, I Muqbil, A Aboukameel, JE Neggers, D Daelemans, ...
Clinical Cancer Research 26 (6), 1338-1348, 2020
272020
Targeting nuclear exporter protein XPO1/CRM1 in gastric cancer
R Sexton, Z Mahdi, R Chaudhury, R Beydoun, A Aboukameel, HY Khan, ...
International Journal of Molecular Sciences 20 (19), 4826, 2019
242019
Mobilization of copper ions in human peripheral lymphocytes by catechins leading to oxidative DNA breakage: A structure activity study
M Farhan, A Zafar, S Chibber, HY Khan, H Arif, SM Hadi
Archives of biochemistry and biophysics 580, 31-40, 2015
242015
Calcium Release-Activated Calcium (CRAC) channel inhibition suppresses pancreatic ductal adenocarcinoma cell proliferation and patient-derived tumor growth
HY Khan, GB Mpilla, R Sexton, S Viswanadha, KV Penmetsa, ...
Cancers 12 (3), 750, 2020
222020
Apogossypolone, derivative of gossypol, mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage
H Zubair, HY Khan, MF Ullah, A Ahmad, D Wu, SM Hadi
European journal of pharmaceutical sciences 47 (1), 280-286, 2012
212012
Targeting XPO1 and PAK4 in 8505C anaplastic thyroid cancer cells: putative implications for overcoming lenvatinib therapy resistance
HY Khan, J Ge, M Nagasaka, A Aboukameel, G Mpilla, I Muqbil, ...
International journal of molecular sciences 21 (1), 237, 2019
172019
Mobilization of intracellular copper by gossypol and apogossypolone leads to reactive oxygen species-mediated cell death: putative anticancer mechanism
H Zubair, S Azim, HY Khan, MF Ullah, D Wu, AP Singh, SM Hadi, ...
International journal of molecular sciences 17 (6), 973, 2016
172016
Desmiflavasides A and B: Two new bioactive pregnane glycosides from the sap of Desmidorchis flava
MA Raees, H Hussain, NU Rehman, HY Khan, G Abbas, A Al-Rawahi, ...
Phytochemistry Letters 12, 153-157, 2015
172015
Synthesis of new boswellic acid derivatives as potential antiproliferative agents
U Shamraiz, H Hussain, N Ur Rehman, S Al-Shidhani, A Saeed, HY Khan, ...
Natural product research 34 (13), 1845-1852, 2020
152020
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