Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity N Modhiran, D Watterson, DA Muller, AK Panetta, DP Sester, L Liu, ... Science translational medicine 7 (304), 304ra142-304ra142, 2015 | 495 | 2015 |
The many faces of the flavivirus NS1 protein offer a multitude of options for inhibitor design D Watterson, N Modhiran, PR Young Antiviral research 130, 7-18, 2016 | 146 | 2016 |
Systems serology detects functionally distinct coronavirus antibody features in children and elderly KJ Selva, CE Van De Sandt, MM Lemke, CY Lee, SK Shoffner, BY Chua, ... Nature communications 12 (1), 2037, 2021 | 133 | 2021 |
Dengue virus NS1 protein activates immune cells via TLR4 but not TLR2 or TLR6 N Modhiran, D Watterson, A Blumenthal, AG Baxter, PR Young, KJ Stacey Immunology and cell biology 95 (5), 491-495, 2017 | 117 | 2017 |
Residues in domain III of the dengue virus envelope glycoprotein involved in cell-surface glycosaminoglycan binding D Watterson, B Kobe, PR Young Journal of General Virology 93 (1), 72-82, 2012 | 116 | 2012 |
Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial KJ Chappell, FL Mordant, Z Li, DK Wijesundara, P Ellenberg, ... The Lancet Infectious Diseases 21 (10), 1383-1394, 2021 | 98 | 2021 |
A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses AA Amarilla, JDJ Sng, R Parry, JM Deerain, JR Potter, YX Setoh, ... Nature Communications 12 (1), 3431, 2021 | 91 | 2021 |
A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus J Hobson-Peters, JJ Harrison, D Watterson, JE Hazlewood, LJ Vet, ... Science translational medicine 11 (522), eaax7888, 2019 | 89 | 2019 |
Quantification of NS1 dengue biomarker in serum via optomagnetic nanocluster detection P Antunes, D Watterson, M Parmvi, R Burger, A Boisen, P Young, ... Scientific Reports 5 (1), 1-10, 2015 | 87 | 2015 |
A broadly protective antibody that targets the flavivirus NS1 protein N Modhiran, H Song, L Liu, C Bletchly, L Brillault, AA Amarilla, X Xu, J Qi, ... Science 371 (6525), 190-194, 2021 | 76 | 2021 |
SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein EA Albornoz, AA Amarilla, N Modhiran, S Parker, XX Li, DK Wijesundara, ... Molecular psychiatry 28 (7), 2878-2893, 2023 | 75 | 2023 |
Synthetic heparan sulfate mimetic pixatimod (PG545) potently inhibits SARS-CoV-2 by disrupting the spike–ACE2 interaction SE Guimond, CJ Mycroft-West, NS Gandhi, JA Tree, TT Le, CM Spalluto, ... ACS central science 8 (5), 527-545, 2022 | 75 | 2022 |
Viral RNA intermediates as targets for detection and discovery of novel and emerging mosquito-borne viruses CA O’Brien, J Hobson-Peters, AWY Yam, AMG Colmant, BJ McLean, ... PLoS neglected tropical diseases 9 (3), e0003629, 2015 | 73 | 2015 |
A novel insect-specific flavivirus replicates only in Aedes-derived cells and persists at high prevalence in wild Aedes vigilax populations in Sydney, Australia BJ McLean, J Hobson-Peters, CE Webb, D Watterson, NA Prow, ... Virology 486, 272-283, 2015 | 60 | 2015 |
A New Clade of Insect-Specific Flaviviruses from Australian Anopheles Mosquitoes Displays Species-Specific Host Restriction AMG Colmant, J Hobson-Peters, H Bielefeldt-Ohmann, AF van den Hurk, ... MSphere 2 (4), 10.1128/msphere. 00262-17, 2017 | 59 | 2017 |
A new species of mesonivirus from the Northern Territory, Australia D Warrilow, D Watterson, RA Hall, SS Davis, R Weir, N Kurucz, P Whelan, ... PloS one 9 (3), e91103, 2014 | 59 | 2014 |
Preclinical development of a molecular clamp‐stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2 D Watterson, DK Wijesundara, N Modhiran, FL Mordant, Z Li, ... Clinical & translational immunology 10 (4), e1269, 2021 | 53 | 2021 |
Phylogenetic diversity of koala retrovirus within a wild koala population KJ Chappell, JC Brealey, AA Amarilla, D Watterson, L Hulse, C Palmieri, ... Journal of virology 91 (3), 10.1128/jvi. 01820-16, 2017 | 52 | 2017 |
Determinants of Zika virus host tropism uncovered by deep mutational scanning YX Setoh, AA Amarilla, NYG Peng, RE Griffiths, J Carrera, ME Freney, ... Nature microbiology 4 (5), 876-887, 2019 | 51 | 2019 |
Potent neutralization of clinical isolates of SARS-CoV-2 D614 and G614 variants by a monomeric, sub-nanomolar affinity nanobody G Valenzuela Nieto, R Jara, D Watterson, N Modhiran, AA Amarilla, ... Scientific reports 11 (1), 3318, 2021 | 50 | 2021 |