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Leonhard Heinz
Leonhard Heinz
Verified email at meduniwien.ac.at
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SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1
M Rebsamen, L Pochini, T Stasyk, MEG De Araújo, M Galluccio, ...
Nature 519 (7544), 477-481, 2015
6882015
Inflammasome activators induce interleukin-1α secretion via distinct pathways with differential requirement for the protease function of caspase-1
O Groß, AS Yazdi, CJ Thomas, M Masin, LX Heinz, G Guarda, M Quadroni, ...
Immunity 36 (3), 388-400, 2012
5612012
DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF‐κB
M Rebsamen, LX Heinz, E Meylan, MC Michallet, K Schroder, K Hofmann, ...
EMBO reports 10 (8), 916-922, 2009
3882009
SARS-CoV-2 vaccination in rituximab-treated patients: B cells promote humoral immune responses in the presence of T-cell-mediated immunity
D Mrak, S Tobudic, M Koblischke, M Graninger, H Radner, D Sieghart, ...
Annals of the rheumatic diseases 80 (10), 1345-1350, 2021
2352021
A conserved circular network of coregulated lipids modulates innate immune responses
MS Köberlin, B Snijder, LX Heinz, CL Baumann, A Fauster, GI Vladimer, ...
Cell 162 (1), 170-183, 2015
2022015
NLRC5 deficiency selectively impairs MHC class I-dependent lymphocyte killing by cytotoxic T cells
F Staehli, K Ludigs, LX Heinz, Q Seguin-Estevez, I Ferrero, M Braun, ...
The Journal of Immunology 188 (8), 3820-3828, 2012
1762012
LZTR1 is a regulator of RAS ubiquitination and signaling
JW Bigenzahn, GM Collu, F Kartnig, M Pieraks, GI Vladimer, LX Heinz, ...
Science 362 (6419), 1171-1177, 2018
1682018
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9
LX Heinz, JE Lee, U Kapoor, F Kartnig, V Sedlyarov, K Papakostas, ...
Nature 581 (7808), 316-322, 2020
1532020
Crystal structure of mammalian acid sphingomyelinase
A Gorelik, K Illes, LX Heinz, G Superti-Furga, B Nagar
Nature communications 7 (1), 1-9, 2016
1062016
The lipid-modifying enzyme SMPDL3B negatively regulates innate immunity
LX Heinz, CL Baumann, MS Köberlin, B Snijder, R Gawish, G Shui, ...
Cell Reports 11 (12), 1919-1928, 2015
1002015
The bicarbonate transporter SLC4A7 plays a key role in macrophage phagosome acidification
V Sedlyarov, R Eichner, E Girardi, P Essletzbichler, U Goldmann, ...
Cell host & microbe 23 (6), 766-774. e5, 2018
762018
Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration
JK Krishnaswamy, A Singh, U Gowthaman, R Wu, P Gorrepati, ...
Proceedings of the National Academy of Sciences 112 (10), 3056-3061, 2015
742015
Differential involvement of PU. 1 and Id2 downstream of TGF-β1 during Langerhans-cell commitment
LX Heinz, B Platzer, PM Reisner, A Jörgl, S Taschner, F Göbel, ...
Blood 107 (4), 1445-1453, 2006
742006
Functional crosstalk between membrane lipids and TLR biology
MS Köberlin, LX Heinz, G Superti-Furga
Current Opinion in Cell Biology 39, 28-36, 2016
592016
A surface biotinylation strategy for reproducible plasma membrane protein purification and tracking of genetic and drug-induced alterations
K Hörmann, A Stukalov, AC Müller, LX Heinz, G Superti-Furga, ...
Journal of proteome research 15 (2), 647-658, 2016
502016
Additional heterologous versus homologous booster vaccination in immunosuppressed patients without SARS-CoV-2 antibody seroconversion after primary mRNA vaccination: a …
M Bonelli, D Mrak, S Tobudic, D Sieghart, M Koblischke, P Mandl, ...
Annals of the rheumatic diseases 81 (5), 687-694, 2022
492022
Human Langerhans-cell activation triggered in vitro by conditionally expressed MKK6 is counterregulated by the downstream effector RelB
A Jörgl, B Platzer, S Taschner, LX Heinz, B Höcher, PM Reisner, ...
Blood 109 (1), 185-193, 2007
442007
Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking
A Fauster, M Rebsamen, KL Willmann, A César-Razquin, E Girardi, ...
Cell Death & Differentiation 26 (6), 1138-1155, 2019
342019
The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade
LX Heinz, M Rebsamen, DC Rossi, F Staehli, K Schroder, M Quadroni, ...
Cell Death & Differentiation 19 (4), 722-731, 2012
332012
Immunogenicity and safety of a fourth COVID-19 vaccination in rituximab-treated patients: an open-label extension study
D Mrak, E Simader, D Sieghart, P Mandl, H Radner, T Perkmann, ...
Annals of the Rheumatic Diseases 81 (12), 1750-1756, 2022
292022
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