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Brian Kuhlman
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Design of a novel globular protein fold with atomic-level accuracy
B Kuhlman, G Dantas, GC Ireton, G Varani, BL Stoddard, D Baker
science 302 (5649), 1364-1368, 2003
20362003
ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules
A Leaver-Fay, M Tyka, SM Lewis, OF Lange, J Thompson, R Jacak, ...
Methods in enzymology 487, 545-574, 2011
19162011
Protein–protein docking with simultaneous optimization of rigid-body displacement and side-chain conformations
JJ Gray, S Moughon, C Wang, O Schueler-Furman, B Kuhlman, CA Rohl, ...
Journal of molecular biology 331 (1), 281-299, 2003
13032003
A genetically encoded photoactivatable Rac controls the motility of living cells
YI Wu, D Frey, OI Lungu, A Jaehrig, I Schlichting, B Kuhlman, KM Hahn
Nature 461 (7260), 104-108, 2009
12402009
The Rosetta all-atom energy function for macromolecular modeling and design
RF Alford, A Leaver-Fay, JR Jeliazkov, MJ O’Meara, FP DiMaio, H Park, ...
Journal of chemical theory and computation 13 (6), 3031-3048, 2017
12222017
Native protein sequences are close to optimal for their structures
B Kuhlman, D Baker
Proceedings of the National Academy of Sciences 97 (19), 10383-10388, 2000
10202000
Labelling and optical erasure of synaptic memory traces in the motor cortex
A Hayashi-Takagi, S Yagishita, M Nakamura, F Shirai, YI Wu, ...
Nature 525 (7569), 333-338, 2015
6682015
Advances in protein structure prediction and design
B Kuhlman, P Bradley
Nature reviews molecular cell biology 20 (11), 681-697, 2019
6342019
Engineering an improved light-induced dimer (iLID) for controlling the localization and activity of signaling proteins
G Guntas, RA Hallett, SP Zimmerman, T Williams, H Yumerefendi, ...
Proceedings of the National Academy of Sciences 112 (1), 112-117, 2015
5972015
Macromolecular modeling and design in Rosetta: recent methods and frameworks
JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ...
Nature methods 17 (7), 665-680, 2020
5462020
A large scale test of computational protein design: folding and stability of nine completely redesigned globular proteins
G Dantas, B Kuhlman, D Callender, M Wong, D Baker
Journal of molecular biology 332 (2), 449-460, 2003
4002003
Serverification of molecular modeling applications: the Rosetta Online Server that Includes Everyone (ROSIE)
S Lyskov, FC Chou, SO Conchuir, BS Der, K Drew, D Kuroda, J Xu, ...
PloS one 8 (5), e63906, 2013
3932013
LOVTRAP: an optogenetic system for photoinduced protein dissociation
H Wang, M Vilela, A Winkler, M Tarnawski, I Schlichting, H Yumerefendi, ...
Nature methods 13 (9), 755-758, 2016
3172016
Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface
SM Lewis, X Wu, A Pustilnik, A Sereno, F Huang, HL Rick, G Guntas, ...
Nature biotechnology 32 (2), 191-198, 2014
2822014
Computer-based redesign of a protein folding pathway
S Nauli, B Kuhlman, D Baker
Nature structural biology 8 (7), 602-605, 2001
2802001
RosettaDesign server for protein design
Y Liu, B Kuhlman
Nucleic acids research 34 (suppl_2), W235-W238, 2006
2612006
Combined covalent-electrostatic model of hydrogen bonding improves structure prediction with Rosetta
MJ O’Meara, A Leaver-Fay, MD Tyka, A Stein, K Houlihan, F DiMaio, ...
Journal of chemical theory and computation 11 (2), 609-622, 2015
2462015
Scientific benchmarks for guiding macromolecular energy function improvement
A Leaver-Fay, MJ O'Meara, M Tyka, R Jacak, Y Song, EH Kellogg, ...
Methods in enzymology 523, 109-143, 2013
2442013
Designing photoswitchable peptides using the AsLOV2 domain
OI Lungu, RA Hallett, EJ Choi, MJ Aiken, KM Hahn, B Kuhlman
Chemistry & biology 19 (4), 507-517, 2012
2382012
E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer
ZM Eletr, DT Huang, DM Duda, BA Schulman, B Kuhlman
Nature structural & molecular biology 12 (10), 933-934, 2005
2212005
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