Paul Dalby
Cited by
Cited by
Strategy and success for the directed evolution of enzymes
PA Dalby
Current opinion in structural biology 21 (4), 473-480, 2011
Optimising enzyme function by directed evolution
PA Dalby
Current opinion in structural biology 13 (4), 500-505, 2003
Accelerated design of bioconversion processes using automated microscale processing techniques
GJ Lye, P Ayazi-Shamlou, F Baganz, PA Dalby, JM Woodley
TRENDS in Biotechnology 21 (1), 29-37, 2003
One‐pot synthesis of amino‐alcohols using a de‐novo transketolase and β‐alanine: Pyruvate transaminase pathway in Escherichia coli
CU Ingram, M Bommer, MEB Smith, PA Dalby, JM Ward, HC Hailes, ...
Biotechnology and bioengineering 96 (3), 559-569, 2007
Two strategies to engineer flexible loops for improved enzyme thermostability
H Yu, Y Yan, C Zhang, PA Dalby
Scientific reports 7 (1), 41212, 2017
Directed evolution of biocatalytic processes
EG Hibbert, F Baganz, HC Hailes, JM Ward, GJ Lye, JM Woodley, ...
Biomolecular engineering 22 (1-3), 11-19, 2005
Directed evolution strategies for improved enzymatic performance
EG Hibbert, PA Dalby
Microbial Cell Factories 4, 1-6, 2005
A multidisciplinary approach toward the rapid and preparative-scale biocatalytic synthesis of chiral amino alcohols: a concise transketolase-/ω-transaminase-mediated synthesis …
MEB Smith, BH Chen, EG Hibbert, U Kaulmann, K Smithies, JL Galman, ...
Organic Process Research & Development 14 (1), 99-107, 2010
Directed evolution of transketolase activity on non-phosphorylated substrates
EG Hibbert, T Senussi, SJ Costelloe, W Lei, MEB Smith, JM Ward, ...
Journal of biotechnology 131 (4), 425-432, 2007
Directed evolution of transketolase substrate specificity towards an aliphatic aldehyde
EG Hibbert, T Senussi, MEB Smith, SJ Costelloe, JM Ward, HC Hailes, ...
Journal of biotechnology 134 (3-4), 240-245, 2008
Evolutionary analysis of the TPP-dependent enzyme family
SJ Costelloe, JM Ward, PA Dalby
Journal of molecular evolution 66, 36-49, 2008
Enhancing and Reversing the Stereoselectivity of Escherichia coli Transketolase via Single‐Point Mutations
MEB Smith, EG Hibbert, AB Jones, PA Dalby, HC Hailes
Advanced Synthesis & Catalysis 350 (16), 2631-2638, 2008
Non-α-hydroxylated aldehydes with evolved transketolase enzymes
A Cázares, JL Galman, LG Crago, MEB Smith, J Strafford, L Ríos-Solís, ...
Organic & biomolecular chemistry 8 (6), 1301-1309, 2010
Engineering enzymes for biocatalysis
PA Dalby
Recent patents on biotechnology 1 (1), 1-9, 2007
High‐throughput measurement of protein stability in microtiter plates
JP Aucamp, AM Cosme, GJ Lye, PA Dalby
Biotechnology and Bioengineering 89 (5), 599-607, 2005
Coupled molecular dynamics mediate long-and short-range epistasis between mutations that affect stability and aggregation kinetics
H Yu, PA Dalby
Proceedings of the National Academy of Sciences 115 (47), E11043-E11052, 2018
Mapping the aggregation kinetics of a therapeutic antibody fragment
N Chakroun, D Hilton, SS Ahmad, GW Platt, PA Dalby
Molecular pharmaceutics 13 (2), 307-319, 2016
The global landscape of approved antibody therapies
X Lyu, Q Zhao, J Hui, T Wang, M Lin, K Wang, J Zhang, J Shentu, ...
Antibody therapeutics 5 (4), 233-257, 2022
Exploiting correlated molecular-dynamics networks to counteract enzyme activity–stability trade-off
H Yu, PA Dalby
Proceedings of the National Academy of Sciences 115 (52), E12192-E12200, 2018
Identification and use of an alkane transporter plug-in for applications in biocatalysis and whole-cell biosensing of alkanes
C Grant, D Deszcz, YC Wei, RJ MartInez-Torres, P Morris, T Folliard, ...
Scientific reports 4 (1), 5844, 2014
The system can't perform the operation now. Try again later.
Articles 1–20