Lyle L. Moldawer
Lyle L. Moldawer
University of Florida College of Medicine
Verified email at - Homepage
TitleCited byYear
Genomic responses in mouse models poorly mimic human inflammatory diseases
J Seok, HS Warren, AG Cuenca, MN Mindrinos, HV Baker, W Xu, ...
Proceedings of the National Academy of Sciences 110 (9), 3507-3512, 2013
A network-based analysis of systemic inflammation in humans
SE Calvano, W Xiao, DR Richards, RM Felciano, HV Baker, RJ Cho, ...
Nature 437 (7061), 1032-1037, 2005
Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo
KJ Van Zee, T Kohno, E Fischer, CS Rock, LL Moldawer, SF Lowry
Proceedings of the National Academy of Sciences 89 (11), 4845-4849, 1992
Antibodies to cachectin/tumor necrosis factor reduce interleukin 1 beta and interleukin 6 appearance during lethal bacteremia.
Y Fong, KJ Tracey, LL Moldawer, DG Hesse, KB Manogue, JS Kenney, ...
The Journal of experimental medicine 170 (5), 1627-1633, 1989
A genomic storm in critically injured humans
W Xiao, MN Mindrinos, J Seok, J Cuschieri, AG Cuenca, H Gao, ...
Journal of Experimental Medicine 208 (13), 2581-2590, 2011
Sepsis syndromes: understanding the role of innate and acquired immunity.
A Oberholzer, C Oberholzer, LL Moldawer
Shock (Augusta, Ga.) 16 (2), 83-96, 2001
Anti-TNF-α therapies: the next generation
MA Palladino, FR Bahjat, EA Theodorakis, LL Moldawer
Nature reviews Drug discovery 2 (9), 736-746, 2003
MyD88-dependent expansion of an immature GR-1+CD11b+ population induces T cell suppression and Th2 polarization in sepsis
MJ Delano, PO Scumpia, JS Weinstein, D Coco, S Nagaraj, ...
The Journal of experimental medicine 204 (6), 1463-1474, 2007
Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties.
SD Wolpe, G Davatelis, B Sherry, B Beutler, DG Hesse, HT Nguyen, ...
The Journal of experimental medicine 167 (2), 570-581, 1988
Cachectin/TNF or IL-1 alpha induces cachexia with redistribution of body proteins
Y Fong, LL Moldawer, M Marano, H Wei, A Barber, K Manogue, KJ Tracey, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 1989
Persistent inflammation and immunosuppression: a common syndrome and new horizon for surgical intensive care
LF Gentile, AG Cuenca, PA Efron, D Ang, BA McKinley, LL Moldawer, ...
The journal of trauma and acute care surgery 72 (6), 1491, 2012
Structural basis for the proinflammatory cytokine activity of high mobility group box 1
J Li, R Kokkola, S Tabibzadeh, R Yang, M Ochani, X Qiang, HE Harris, ...
Molecular Medicine 9 (1-2), 37-45, 2003
Inflammation and Host Response to Injury, Large Scale Collaborative Research Program. Genomic responses in mouse models poorly mimic human inflammatory diseases
J Seok, HS Warren, AG Cuenca, MN Mindrinos, HV Baker, W Xu, ...
Proc Natl Acad Sci USA 110 (9), 3507-3512, 2013
The biologic characteristics of cytokines and their implication in surgical injury.
Y Fong, LL Moldawer, GT Shires, SF Lowry
Surgery, gynecology & obstetrics 170 (4), 363-378, 1990
The acute splanchnic and peripheral tissue metabolic response to endotoxin in humans.
YM Fong, MA Marano, LL Moldawer, H Wei, SE Calvano, JS Kenney, ...
The Journal of clinical investigation 85 (6), 1896-1904, 1990
IL-8 in septic shock, endotoxemia, and after IL-1 administration.
KJ Van Zee, LE DeForge, E Fischer, MA Marano, JS Kenney, DG Remick, ...
The Journal of immunology 146 (10), 3478-3482, 1991
A mouse model for investigating the molecular pathogenesis of adenovirus pneumonia
HS Ginsberg, LL Moldawer, PB Sehgal, M Redington, PL Kilian, ...
Proceedings of the National Academy of Sciences 88 (5), 1651-1655, 1991
Serum cachectin/tumor necrosis factor in critically ill patients with burns correlates with infection and mortality.
MA Marano, Y Fong, LL Moldawer, H Wei, SE Calvano, KJ Tracey, ...
Surgery, gynecology & obstetrics 170 (1), 32-38, 1990
Absence of IL-1 signaling and reduced inflammatory response in IL-1 type I receptor-deficient mice.
M Labow, D Shuster, M Zetterstrom, P Nunes, R Terry, EB Cullinan, ...
The Journal of Immunology 159 (5), 2452-2461, 1997
Apoptosis in sepsis: a new target for therapeutic exploration
The FASEB Journal 15 (6), 879-892, 2001
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