CellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms C Terfve, T Cokelaer, D Henriques, A MacNamara, E Goncalves, ... BMC systems biology 6, 1-14, 2012 | 249 | 2012 |
MEIGO: an open-source software suite based on metaheuristics for global optimization in systems biology and bioinformatics JA Egea, D Henriques, T Cokelaer, AF Villaverde, A MacNamara, ... BMC bioinformatics 15, 1-9, 2014 | 200 | 2014 |
HLA class I binding of HBZ determines outcome in HTLV-1 infection A MacNamara, A Rowan, S Hilburn, U Kadolsky, H Fujiwara, K Suemori, ... PLoS pathogens 6 (9), e1001117, 2010 | 170 | 2010 |
KIR2DL2 Enhances Protective and Detrimental HLA Class I-Mediated Immunity in Chronic Viral Infection NK Seich al Basatena, A MacNamara, AM Vine, CL Thio, J Astemborski, ... PLoS pathogens 7 (10), e1002270, 2011 | 95 | 2011 |
State–time spectrum of signal transduction logic models A MacNamara, C Terfve, D Henriques, BP Bernabé, J Saez-Rodriguez Physical biology 9 (4), 045003, 2012 | 90 | 2012 |
A rapidly reversible chemical dimerizer system to study lipid signaling in living cells S Feng, V Laketa, F Stein, A Rutkowska, A MacNamara, S Depner, ... Angewandte Chemie 126 (26), 6838-6841, 2014 | 87 | 2014 |
In vivo expression of human T-lymphotropic virus type 1 basic leucine-zipper protein generates specific CD8+ and CD4+ T-lymphocyte responses that correlate with clinical outcome S Hilburn, A Rowan, MA Demontis, A MacNamara, B Asquith, ... Journal of Infectious Diseases 203 (4), 529-536, 2011 | 80 | 2011 |
The avidity and lytic efficiency of the CTL response to HTLV-1 T Kattan, A MacNamara, AG Rowan, H Nose, AJ Mosley, Y Tanaka, ... The Journal of Immunology 182 (9), 5723-5729, 2009 | 75 | 2009 |
Modeling signaling networks to advance new cancer therapies J Saez-Rodriguez, A MacNamara, S Cook Annual review of biomedical engineering 17 (1), 143-163, 2015 | 47 | 2015 |
PIP3 induces the recycling of receptor tyrosine kinases V Laketa, S Zarbakhsh, A Traynor-Kaplan, A MacNamara, ... Science signaling 7 (308), ra5-ra5, 2014 | 47 | 2014 |
T-cell epitope prediction: rescaling can mask biological variation between MHC molecules A MacNamara, U Kadolsky, CRM Bangham, B Asquith PLoS computational biology 5 (3), e1000327, 2009 | 41 | 2009 |
Genetic and environmental determinants of diastolic heart function M Thanaj, J Mielke, KA McGurk, W Bai, N Savioli, A de Marvao, HV Meyer, ... Nature cardiovascular research 1 (4), 361-371, 2022 | 24 | 2022 |
Network and pathway expansion of genetic disease associations identifies successful drug targets A MacNamara, N Nakic, A Amin Al Olama, C Guo, KB Sieber, MR Hurle, ... Scientific reports 10 (1), 20970, 2020 | 19 | 2020 |
In contrast to HIV, KIR3DS1 does not influence outcome in HTLV-1 retroviral infection GM O’Connor, NKS Al Basatena, V Olavarria, A MacNamara, A Vine, ... Human immunology 73 (8), 783-787, 2012 | 11 | 2012 |
Modeling signaling networks with different formalisms: a preview A MacNamara, D Henriques, J Saez-Rodriguez In Silico Systems Biology, 89-105, 2013 | 7 | 2013 |
Experimental and computational analysis of newly identified pathogenic mutations in the creatine transporter SLC6A8 E Ferrada, T Wiedmer, WA Wang, F Frommelt, B Steurer, C Klimek, ... Journal of Molecular Biology 436 (2), 168383, 2024 | 6 | 2024 |
ProteoMutaMetrics: machine learning approaches for solute carrier family 6 mutation pathogenicity prediction J Huang, T Osthushenrich, A MacNamara, A Mälarstig, S Brocchetti, ... RSC advances 14 (19), 13083-13094, 2024 | 4 | 2024 |
Data-and knowledge-derived functional landscape of human solute carriers U Goldmann, T Wiedmer, A Garofoli, V Sedlyarov, M Bichler, G Wolf, ... BioRxiv, 2024.10. 14.618155, 2024 | 3 | 2024 |
A single-cell model of PIP3 dynamics using chemical dimerization A MacNamara, F Stein, S Feng, C Schultz, J Saez-Rodriguez Bioorganic & Medicinal Chemistry 23 (12), 2868-2876, 2015 | 3 | 2015 |
An IFN-γ ELISPOT assay with two CTL epitopes derived from HTLV-1 Tax region 161-233 discriminates HAM/TSP patients from asymptomatic HTLV-1 carriers in a Peruvian population. I Best, G López, M Talledo, A Macnamara, K Verdonck, E González, ... AIDS research and human retroviruses, 2011 | 3* | 2011 |