| The consensus molecular subtypes of colorectal cancer J Guinney, R Dienstmann, X Wang, A De Reynies, A Schlicker, ... Nature medicine 21 (11), 1350-1356, 2015 | 4944 | 2015 |
| Wnt activity defines colon cancer stem cells and is regulated by the microenvironment L Vermeulen, F De Sousa E Melo, M Van Der Heijden, K Cameron, ... Nature cell biology 12 (5), 468-476, 2010 | 2113 | 2010 |
| Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4 M Todaro, MP Alea, AB Di Stefano, P Cammareri, L Vermeulen, F Iovino, ... Cell stem cell 1 (4), 389-402, 2007 | 1355 | 2007 |
| Consensus molecular subtypes and the evolution of precision medicine in colorectal cancer R Dienstmann, L Vermeulen, J Guinney, S Kopetz, S Tejpar, J Tabernero Nature reviews cancer 17 (2), 79-92, 2017 | 1022 | 2017 |
| Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity L Vermeulen, M Todaro, F de Sousa Mello, MR Sprick, K Kemper, ... Proceedings of the National Academy of Sciences 105 (36), 13427-13432, 2008 | 926 | 2008 |
| Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions F De Sousa E Melo, X Wang, M Jansen, E Fessler, A Trinh, ... Nature medicine 19 (5), 614-618, 2013 | 889 | 2013 |
| Intestinal label-retaining cells are secretory precursors expressing Lgr5 SJA Buczacki, HI Zecchini, AM Nicholson, R Russell, L Vermeulen, ... Nature 495 (7439), 65-69, 2013 | 875 | 2013 |
| Cancer stem cell niche: the place to be T Borovski, F De Sousa E Melo, L Vermeulen, JP Medema Cancer research 71 (3), 634-639, 2011 | 664 | 2011 |
| Microenvironmental regulation of stem cells in intestinal homeostasis and cancer JP Medema, L Vermeulen Nature 474 (7351), 318-326, 2011 | 624 | 2011 |
| From tumour heterogeneity to advances in precision treatment of colorectal cancer CJA Punt, M Koopman, L Vermeulen Nature reviews Clinical oncology 14 (4), 235-246, 2017 | 607 | 2017 |
| The developing cancer stem-cell model: clinical challenges and opportunities L Vermeulen, FS e Melo, DJ Richel, JP Medema The lancet oncology 13 (2), e83-e89, 2012 | 477 | 2012 |
| Cancer stem cells–old concepts, new insights L Vermeulen, MR Sprick, K Kemper, G Stassi, JP Medema Cell Death & Differentiation 15 (6), 947-958, 2008 | 466 | 2008 |
| The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation K Kemper, MR Sprick, M de Bree, A Scopelliti, L Vermeulen, M Hoek, ... Cancer research 70 (2), 719-729, 2010 | 464 | 2010 |
| Defining stem cell dynamics in models of intestinal tumor initiation L Vermeulen, E Morrissey, M Van Der Heijden, AM Nicholson, A Sottoriva, ... Science 342 (6161), 995-998, 2013 | 445 | 2013 |
| Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients EM Felipe de Sousa, S Colak, J Buikhuisen, J Koster, K Cameron, ... Cell stem cell 9 (5), 476-485, 2011 | 363 | 2011 |
| Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead WH Goodson III, L Lowe, DO Carpenter, M Gilbertson, A Manaf Ali, ... Carcinogenesis 36 (Suppl_1), S254-S296, 2015 | 358 | 2015 |
| Cancer heterogeneity—a multifaceted view FDSE Melo, L Vermeulen, E Fessler, JP Medema EMBO reports 14 (8), 686-695, 2013 | 323 | 2013 |
| Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study E Domingo, L Freeman-Mills, E Rayner, M Glaire, S Briggs, L Vermeulen, ... The lancet Gastroenterology & hepatology 1 (3), 207-216, 2016 | 318 | 2016 |
| Stem cell dynamics in homeostasis and cancer of the intestine L Vermeulen, HJ Snippert Nature Reviews Cancer 14 (7), 468-480, 2014 | 263 | 2014 |
| Targeting Wnt signaling in colon cancer stem cells EMF de Sousa, L Vermeulen, D Richel, JP Medema Clinical Cancer Research 17 (4), 647-653, 2011 | 256 | 2011 |
jan paul medemaHoogleraar Exp Oncology and RadiobiologyVerified email at amc.nl
