Tilmann Bürckstümmer
Tilmann Bürckstümmer
Aelian Biotechnology
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An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
T Bürckstümmer, C Baumann, S Blüml, E Dixit, G Dürnberger, H Jahn, ...
Nature immunology 10 (3), 266-272, 2009
IFIT1 is an antiviral protein that recognizes 5 [prime]-triphosphate RNA
A Pichlmair, C Lassnig, CA Eberle, MW Górna, CL Baumann, TR Burkard, ...
Nature immunology 12 (7), 624-630, 2011
An efficient tandem affinity purification procedure for interaction proteomics in mammalian cells
T Bürckstümmer, KL Bennett, A Preradovic, G Schütze, O Hantschel, ...
Nature methods 3 (12), 1013-1019, 2006
The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response
D Soulat, T Bürckstümmer, S Westermayer, A Goncalves, A Bauch, ...
The EMBO journal 27 (15), 2135-2146, 2008
The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib
O Hantschel, U Rix, U Schmidt, T Bürckstümmer, M Kneidinger, G Schütze, ...
Proceedings of the National Academy of Sciences 104 (33), 13283-13288, 2007
Megabase-scale deletion using CRISPR/Cas9 to generate a fully haploid human cell line
P Essletzbichler, T Konopka, F Santoro, D Chen, BV Gapp, R Kralovics, ...
Genome Research, gr. 177220.114, 2014
Viral immune modulators perturb the human molecular network by common and unique strategies
A Pichlmair, K Kandasamy, G Alvisi, O Mulhern, R Sacco, M Habjan, ...
Nature, 2012
Biological plasticity rescues target activity in CRISPR knock outs
AH Smits, F Ziebell, G Joberty, N Zinn, WF Mueller, S Clauder-Münster, ...
Nature methods 16 (11), 1087-1093, 2019
A generic strategy for CRISPR-Cas9-mediated gene tagging
DH Lackner, A Carré, PM Guzzardo, C Banning, R Mangena, T Henley, ...
Nature Communications 6, 2015
SAMHD1 is a nucleic‐acid binding protein that is mislocalized due to aicardi–goutières syndrome‐associated mutations
A Goncalves, E Karayel, GI Rice, KL Bennett, YJ Crow, G Superti‐Furga, ...
Human Mutation, 2012
Functional dissection of the TBK1 molecular network
A Goncalves, T Bürckstümmer, E Dixit, R Scheicher, MW Górna, E Karayel, ...
PloS one 6 (9), e23971, 2011
A reversible gene trap collection empowers haploid genetics in human cells
T Bürckstümmer, C Banning, P Hainzl, R Schobesberger, C Kerzendorfer, ...
Nature methods 10 (10), 965-971, 2013
Initial characterization of the human central proteome
TR Burkard, M Planyavsky, I Kaupe, FP Breitwieser, T Bürckstümmer, ...
BMC systems biology 5 (1), 17, 2011
Multiple differences in agonist and antagonist pharmacology between human and guinea pig histamine H1-receptor
R Seifert, K Wenzel-Seifert, T Bürckstümmer, HH Pertz, W Schunack, ...
Journal of Pharmacology and Experimental Therapeutics 305 (3), 1104-1115, 2003
Raf-1 kinase associates with Hepatitis C virus NS5A and regulates viral replication
T Bürckstümmer, M Kriegs, J Lupberger, EK Pauli, S Schmittel, E Hildt
FEBS letters 580 (2), 575-580, 2006
Distinct interaction of human and guinea pig histamine H2-receptor with guanidine-type agonists
MT Kelley, T Bürckstümmer, K Wenzel-Seifert, S Dove, A Buschauer, ...
Molecular Pharmacology 60 (6), 1210-1225, 2001
The human histamine H2‐receptor couples more efficiently to Sf9 insect cell Gs‐proteins than to insect cell Gq‐proteins: limitations of Sf9 cells for the analysis of receptor …
C Houston, K Wenzel‐Seifert, T Bürckstümmer, R Seifert
Journal of neurochemistry 80 (4), 678-696, 2002
The hepatitis C virus non-structural NS5A protein impairs both the innate and adaptive hepatic immune response in vivo
M Kriegs, T Bürckstümmer, K Himmelsbach, M Bruns, L Frelin, G Ahlén, ...
Journal of Biological Chemistry 284 (41), 28343-28351, 2009
The TLR‐independent DNA recognition pathway in murine macrophages: Ligand features and molecular signature
E Karayel, T Bürckstümmer, M Bilban, G Dürnberger, S Weitzer, ...
European journal of immunology 39 (7), 1929-1936, 2009
Efficient generation and reversion of chromosomal translocations using CRISPR/Cas technology
S Lekomtsev, S Aligianni, A Lapao, T Bürckstümmer
BMC Genomics 17 (1), 739, 2016
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