Michael V Holmes
Michael V Holmes
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Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians
NM Davies, MV Holmes, GD Smith
bmj 362, 2018
Guidelines for performing Mendelian randomization investigations: update for summer 2023
S Burgess, GD Smith, NM Davies, F Dudbridge, D Gill, MM Glymour, ...
Wellcome open research 4, 2019
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis
Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium
The Lancet 379 (9822), 1214-1224, 2012
Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data
MV Holmes, CE Dale, L Zuccolo, RJ Silverwood, Y Guo, Z Ye, ...
Bmj 349, g4164, 2014
Mendelian randomization of blood lipids for coronary heart disease
MV Holmes, FW Asselbergs, TM Palmer, F Drenos, MB Lanktree, ...
European heart journal 36 (9), 539-550, 2015
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials
DI Swerdlow, D Preiss, KB Kuchenbaecker, MV Holmes, JEL Engmann, ...
The Lancet 385 (9965), 351-361, 2015
Mendelian randomization
E Sanderson, MM Glymour, MV Holmes, H Kang, J Morrison, MR Munaf˛, ...
Nature Reviews Methods Primers 2 (1), 6, 2022
Meta‐analysis and Mendelian randomization: a review
J Bowden, MV Holmes
Research synthesis methods 10 (4), 486-496, 2019
CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: a systematic review and meta-analysis
MV Holmes, P Perel, T Shah, AD Hingorani, JP Casas
Jama 306 (24), 2704-2714, 2011
Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: a multivariable Mendelian randomisation analysis
TG Richardson, E Sanderson, TM Palmer, M Ala-Korpela, BA Ference, ...
PLoS medicine 17 (3), e1003062, 2020
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure
S Shah, A Henry, C Roselli, H Lin, G Sveinbj÷rnsson, G Fatemifar, ...
Nature communications 11 (1), 163, 2020
Mendelian randomization in cardiometabolic disease: challenges in evaluating causality
MV Holmes, M Ala-Korpela, GD Smith
Nature Reviews Cardiology 14 (10), 577-590, 2017
Association between diabetes and cause-specific mortality in rural and urban areas of China
F Bragg, MV Holmes, A Iona, Y Guo, H Du, Y Chen, Z Bian, L Yang, ...
Jama 317 (3), 280-289, 2017
Conventional and genetic evidence on alcohol and vascular disease aetiology: a prospective study of 500 000 men and women in China
IY Millwood, RG Walters, XW Mei, Y Guo, L Yang, Z Bian, DA Bennett, ...
The Lancet 393 (10183), 1831-1842, 2019
The power of genetic diversity in genome-wide association studies of lipids
SE Graham, SL Clarke, KHH Wu, S Kanoni, GJM Zajac, S Ramdas, ...
Nature 600 (7890), 675-679, 2021
Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials
MV Holmes, P Newcombe, JA Hubacek, R Sofat, SL Ricketts, J Cooper, ...
The Lancet 378 (9791), 584-594, 2011
Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases
J Zheng, V Haberland, D Baird, V Walker, PC Haycock, MR Hurle, ...
Nature genetics 52 (10), 1122-1131, 2020
PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study
AF Schmidt, DI Swerdlow, MV Holmes, RS Patel, Z Fairhurst-Hunter, ...
The lancet Diabetes & endocrinology 5 (2), 97-105, 2017
Lipids, lipoproteins, and metabolites and risk of myocardial infarction and stroke
MV Holmes, IY Millwood, C Kartsonaki, MR Hill, DA Bennett, R Boxall, ...
Journal of The American college of cardiology 71 (6), 620-632, 2018
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals
L Folkersen, S Gustafsson, Q Wang, DH Hansen, ┼K Hedman, A Schork, ...
Nature metabolism 2 (10), 1135-1148, 2020
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