frank speleman
frank speleman
Professor of Medical Genetics, Ghent University, Belgium
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Year
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
J Vandesompele, K De Preter, F Pattyn, B Poppe, N Van Roy, ...
Genome biology 3 (7), research0034. 1, 2002
167972002
qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data
J Hellemans, G Mortier, A De Paepe, F Speleman, J Vandesompele
Genome biology 8 (2), 1-14, 2007
32032007
miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis
L Ma, J Young, H Prabhala, E Pan, P Mestdagh, D Muth, ...
Nature cell biology 12 (3), 247-256, 2010
13382010
Identification of ALK as a major familial neuroblastoma predisposition gene
YP Mossé, M Laudenslager, L Longo, KA Cole, A Wood, EF Attiyeh, ...
Nature 455 (7215), 930-935, 2008
11852008
A novel and universal method for microRNA RT-qPCR data normalization
P Mestdagh, P Van Vlierberghe, A De Weer, D Muth, F Westermann, ...
Genome biology 10 (6), 1-10, 2009
8892009
Loss-of-function mutations in FGFR1 cause autosomal dominant Kallmann syndrome
C Dodé, J Levilliers, JM Dupont, A De Paepe, N Le Dû, ...
Nature genetics 33 (4), 463-465, 2003
8242003
Acquired mutations in TET2 are common in myelodysplastic syndromes
SMC Langemeijer, RP Kuiper, M Berends, R Knops, MG Aslanyan, ...
Nature genetics 41 (7), 838-842, 2009
7812009
Recurrent rearrangements of chromosome 1q21. 1 and variable pediatric phenotypes
HC Mefford, AJ Sharp, C Baker, A Itsara, Z Jiang, K Buysse, S Huang, ...
New England Journal of Medicine 359 (16), 1685-1699, 2008
7152008
Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma
N Bown, S Cotterill, M Łastowska, S O'Neill, ADJ Pearson, D Plantaz, ...
New England Journal of Medicine 340 (25), 1954-1961, 1999
5271999
EWS and ATF-1 gene fusion induced by t (12; 22) translocation in malignant melanoma of soft parts
J Zucman, O Delattre, C Desmaze, AL Epstein, G Stenman, F Speleman, ...
Nature genetics 4 (4), 341-345, 1993
5101993
Exhaustive mutation analysis of the NF1 gene allows identification of 95% of mutations and reveals a high frequency of unusual splicing defects
LM Messiaen, T Callens, G Mortier, D Beysen, I Vandenbroucke, ...
Human mutation 15 (6), 541-555, 2000
4982000
Emerging patterns of cryptic chromosomal imbalance in patients with idiopathic mental retardation and multiple congenital anomalies: a new series of 140 patients and review of …
B Menten, N Maas, B Thienpont, K Buysse, J Vandesompele, C Melotte, ...
Journal of medical genetics 43 (8), 625-633, 2006
4332006
Loss-of-function mutations in LEMD3 result in osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis
J Hellemans, O Preobrazhenska, A Willaert, P Debeer, PCM Verdonk, ...
Nature genetics 36 (11), 1213-1218, 2004
4322004
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer
AL Wolfe, K Singh, Y Zhong, P Drewe, VK Rajasekhar, VR Sanghvi, ...
Nature 513 (7516), 65-70, 2014
3402014
High-throughput stem-loop RT-qPCR miRNA expression profiling using minute amounts of input RNA
P Mestdagh, T Feys, N Bernard, S Guenther, C Chen, F Speleman, ...
Nucleic acids research 36 (21), e143-e143, 2008
3182008
International consensus for neuroblastoma molecular diagnostics: report from the International Neuroblastoma Risk Group (INRG) Biology Committee
PF Ambros, IM Ambros, GM Brodeur, M Haber, J Khan, A Nakagawara, ...
British journal of cancer 100 (9), 1471-1482, 2009
2972009
Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations
YC Lin, M Boone, L Meuris, I Lemmens, N Van Roy, A Soete, J Reumers, ...
Nature communications 5 (1), 1-12, 2014
2932014
Elimination of primer–dimer artifacts and genomic coamplification using a two-step SYBR green I real-time RT-PCR
J Vandesompele, A De Paepe, F Speleman
Analytical biochemistry 303 (1), 95-98, 2002
2922002
The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma
P Mestdagh, AK Boström, F Impens, E Fredlund, G Van Peer, ...
Molecular cell 40 (5), 762-773, 2010
2852010
Overall genomic pattern is a predictor of outcome in neuroblastoma
I Janoueix-Lerosey, G Schleiermacher, E Michels, V Mosseri, A Ribeiro, ...
Journal of clinical oncology 27 (7), 1026-1033, 2009
2762009
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