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Pavel Marichal-Gallardo
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State‐of‐the‐art in downstream processing of monoclonal antibodies: Process trends in design and validation
PA Marichal‐Gallardo, MM Alvarez
Biotechnology progress 28 (4), 899-916, 2012
1862012
Steric exclusion chromatography for purification of cell culture-derived influenza A virus using regenerated cellulose membranes and polyethylene glycol
P Marichal-Gallardo, MM Pieler, MW Wolff, U Reichl
Journal of Chromatography A 1483, 110-119, 2017
672017
Efficient influenza A virus production in high cell density using the novel porcine suspension cell line PBG. PK2. 1
G Gränicher, J Coronel, A Pralow, P Marichal-Gallardo, M Wolff, E Rapp, ...
Vaccine 37 (47), 7019-7028, 2019
362019
Single-use capture purification of adeno-associated viral gene transfer vectors by membrane-based steric exclusion chromatography
P Marichal-Gallardo, K Börner, MM Pieler, V Sonntag-Buck, M Obr, ...
Human Gene Therapy 32 (17-18), 959-974, 2021
312021
OP7, a novel influenza A virus defective interfering particle: production, purification, and animal experiments demonstrating antiviral potential
MD Hein, H Kollmus, P Marichal-Gallardo, S Püttker, D Benndorf, ...
Applied microbiology and biotechnology 105, 129-146, 2021
242021
Antiviral activity of influenza A virus defective interfering particles against SARS-CoV-2 replication in vitro through stimulation of innate immunity
U Rand, SY Kupke, H Shkarlet, MD Hein, T Hirsch, P Marichal-Gallardo, ...
Cells 10 (7), 1756, 2021
232021
Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles
MD Hein, P Arora, P Marichal-Gallardo, M Winkler, Y Genzel, S Pöhlmann, ...
BMC biology 19 (1), 91, 2021
222021
Towards integrated production of an influenza A vaccine candidate with MDCK suspension cells
T Bissinger, Y Wu, P Marichal‐Gallardo, D Riedel, X Liu, Y Genzel, ...
Biotechnology and Bioengineering 118 (10), 3996-4013, 2021
152021
A high cell density perfusion process for Modified Vaccinia virus Ankara production: Process integration with inline DNA digestion and cost analysis
G Gränicher, M Babakhani, S Göbel, I Jordan, P Marichal‐Gallardo, ...
Biotechnology and Bioengineering 118 (12), 4720-4734, 2021
142021
Multi‐enzyme cascades for the in vitro synthesis of guanosine diphosphate L‐fucose
R Mahour, P Marichal-Gallardo, T Rexer, U Reichl
ChemCatChem, 2020
142020
Chromatographic purification of biological macromolecules by their capture on hydrophilic surfaces with the aid of non-ionic polymers
P Marichal-Gallardo
Otto-von-Guericke-Universität Magdeburg, 2019
72019
A baseline process for the production, recovery, and purification of bacterial influenza vaccine candidates
PB Sánchez‐Arreola, S López‐Uriarte, PA Marichal‐Gallardo, ...
Biotechnology progress 29 (4), 896-908, 2013
72013
Purifying viruses with a sheet of paper: single-use steric exclusion chromatography as a capture platform for vaccine candidates
P Marichal-Gallardo, AR Fortuna, Y Genzel, M Wolff, U Reichl
52018
Broad-spectrum antiviral activity of Influenza A defective interfering particles against respiratory syncytial, Yellow Fever, and Zika Virus replication in vitro
L Pelz, E Piagnani, P Marsall, N Wynserski, MD Hein, P Marichal-Gallardo, ...
Viruses 15 (9), 1872, 2023
42023
Generation of “OP7 chimera” defective interfering influenza A particle preparations free of infectious virus that show antiviral efficacy in mice
T Dogra, L Pelz, JD Boehme, J Kuechler, O Kershaw, P Marichal-Gallardo, ...
Scientific Reports 13 (1), 20936, 2023
22023
Method for the separation of virus compositions including depletion and purification thereof
M Wolff, MM Pieler, U Reichl, P Marichal-gallardo
US Patent 11,697,800, 2023
12023
An inactivated SARS-CoV-2 vaccine induced cross-neutralizing persisting antibodies and protected against challenge in small animals
A Offersgaard, CRD Hernandez, S Feng, P Marichal-Gallardo, ...
Iscience 26 (2), 2023
12023
Integrated production of an influenza A vaccine candidate with MDCK suspension cells
T Bissinger, Y Wu, P Marichal-Gallardo, D Riedel, X Liu, Y Genzel, ...
Authorea Preprints, 2021
12021
Antiviral activity of influenza A virus defective interfering particles against SARS-CoV-2 replication in vitro through stimulation of innate immunity. Cells. 2021; 10 (7): 1756
U Rand, SY Kupke, H Shkarlet, MD Hein, T Hirsch, P Marichal-Gallardo, ...
s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021
12021
A single-use chromatographic purification platform for viral gene transfer vectors & viral vaccines
P. Marichal-Gallardo, Y. Genzel, K. Börner, D. Grimm, Michael W. Wolff, U ...
Advancing Manufacture of Cell and Gene Therapies VI, 2019
12019
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