James Solomon Fraser
James Solomon Fraser
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Cited by
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ...
Nature 583 (7816), 459-468, 2020
EMRinger: side chain–directed model and map validation for 3D cryo-electron microscopy
BA Barad, N Echols, RYR Wang, Y Cheng, F DiMaio, PD Adams, ...
Nature methods 12 (10), 943-946, 2015
Accessing protein conformational ensembles using room-temperature X-ray crystallography
JS Fraser, H van den Bedem, AJ Samelson, PT Lang, JM Holton, ...
Proceedings of the National Academy of Sciences 108 (39), 16247-16252, 2011
Hidden alternative structures of proline isomerase essential for catalysis
JS Fraser, MW Clarkson, SC Degnan, R Erion, D Kern, T Alber
Nature 462 (7273), 669-673, 2009
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ...
Science 370 (6521), eabe9403, 2020
Promoting transparency and reproducibility in enhanced molecular simulations
M Bonomi, G Bussi, C Camilloni, GA Tribello, P Banáš, A Barducci, ...
Nature methods 16 (8), 670-673, 2019
Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine
BB Williams, AH Van Benschoten, P Cimermancic, MS Donia, ...
Cell host & microbe 16 (4), 495-503, 2014
Systematic functional prioritization of protein posttranslational modifications
P Beltrao, V Albanèse, LR Kenner, DL Swaney, A Burlingame, J Villén, ...
Cell 150 (2), 413-425, 2012
Automated structure refinement of macromolecular assemblies from cryo-EM maps using Rosetta
RYR Wang, Y Song, BA Barad, Y Cheng, JS Fraser, F DiMaio
Elife 5, e17219, 2016
Effects of α-tubulin acetylation on microtubule structure and stability
L Eshun-Wilson, R Zhang, D Portran, MV Nachury, DB Toso, T Löhr, ...
Proceedings of the National Academy of Sciences 116 (21), 10366-10371, 2019
Integrative, dynamic structural biology at atomic resolution - it's about time
H van den Bedem, JS Fraser
Nature methods 12 (4), 307-318, 2015
Ig-like domains on bacteriophages: a tale of promiscuity and deceit
JS Fraser, Z Yu, KL Maxwell, AR Davidson
Journal of molecular biology 359 (2), 496-507, 2006
Preprints for the life sciences
JM Berg, N Bhalla, PE Bourne, M Chalfie, DG Drubin, JS Fraser, ...
Science 352 (6288), 899-901, 2016
Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR
RB Fenwick, H van den Bedem, JS Fraser, PE Wright
Proceedings of the National Academy of Sciences 111 (4), E445-E454, 2014
CryptoSite: expanding the druggable proteome by characterization and prediction of cryptic binding sites
P Cimermancic, P Weinkam, TJ Rettenmaier, L Bichmann, DA Keedy, ...
Journal of molecular biology 428 (4), 709-719, 2016
Automated electron‐density sampling reveals widespread conformational polymorphism in proteins
PT Lang, HL Ng, JS Fraser, JE Corn, N Echols, M Sales, JM Holton, ...
Protein Science 19 (7), 1420-1431, 2010
Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography
DA Keedy, LR Kenner, M Warkentin, RA Woldeyes, JB Hopkins, ...
Elife 4, e07574, 2015
From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II
H Braberg, H Jin, EA Moehle, YA Chan, S Wang, M Shales, JJ Benschop, ...
Cell 154 (4), 775-788, 2013
Automated identification of functional dynamic contact networks from X-ray crystallography
H Van Den Bedem, G Bhabha, K Yang, PE Wright, JS Fraser
Nature methods 10 (9), 896-902, 2013
Incorporation of protein flexibility and conformational energy penalties in docking screens to improve ligand discovery
M Fischer, RG Coleman, JS Fraser, BK Shoichet
Nature chemistry 6 (7), 575-583, 2014
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