Hexokinase 1 cellular localization regulates the metabolic fate of glucose A De Jesus, F Keyhani-Nejad, CM Pusec, L Goodman, JA Geier, ... Molecular cell 82 (7), 1261-1277. e9, 2022 | 51 | 2022 |
Targeting latent TGFβ release in muscular dystrophy E Ceco, S Bogdanovich, B Gardner, T Miller, A DeJesus, JU Earley, ... Science translational medicine 6 (259), 259ra144-259ra144, 2014 | 50 | 2014 |
Hepatic HKDC1 expression contributes to liver metabolism CM Pusec, A De Jesus, MW Khan, AR Terry, AE Ludvik, K Xu, N Giancola, ... Endocrinology 160 (2), 313-330, 2019 | 47 | 2019 |
Hepatocyte-specific loss of PPARγ protects mice from NASH and increases the therapeutic effects of rosiglitazone in the liver SM Lee, CM Pusec, GH Norris, A De Jesus, A Diaz-Ruiz, J Muratalla, ... Cellular and molecular gastroenterology and hepatology 11 (5), 1291-1311, 2021 | 33 | 2021 |
Hepatic tristetraprolin promotes insulin resistance through RNA destabilization of FGF21 KT Sawicki, HC Chang, JS Shapiro, M Bayeva, A De Jesus, BN Finck, ... JCI insight 3 (13), 2018 | 32 | 2018 |
Iron metabolism in cardiovascular disease: physiology, mechanisms, and therapeutic targets KT Sawicki, A De Jesus, H Ardehali Circulation research 132 (3), 379-396, 2023 | 24 | 2023 |
ZFP36L2 suppresses mTORc1 through a P53-dependent pathway to prevent peripartum cardiomyopathy in mice H Kouzu, Y Tatekoshi, HC Chang, JS Shapiro, WA McGee, A De Jesus, ... The Journal of Clinical Investigation 132 (10), 2022 | 11 | 2022 |
Iron drives anabolic metabolism through active histone demethylation and mTORC1 JS Shapiro, HC Chang, Y Tatekoshi, Z Zhao, ZS Waxali, BJ Hong, H Chen, ... Nature Cell Biology 25 (10), 1478-1494, 2023 | 6 | 2023 |
Optimized protocol to isolate primary mouse peritoneal macrophage metabolites A De Jesus, CM Pusec, T Nguyen, F Keyhani-Nejad, P Gao, SE Weinberg, ... STAR protocols 3 (4), 101668, 2022 | 3 | 2022 |
Metabolic suppression of HIF-1α contributes to susceptibility of ischemic injury in diabetic hearts A De Jesus, HC Chang, H Ardehali JACC: Basic to Translational Science 3 (4), 499-502, 2018 | 3 | 2018 |
Liver-specific overexpression of HKDC1 increases hepatocyte size and proliferative capacity CM Pusec, V Ilievski, A De Jesus, Z Farooq, JL Zapater, N Sweis, H Ismail, ... Scientific reports 13 (1), 8034, 2023 | 1 | 2023 |
Hexokinase-1 mitochondrial dissociation and protein O-GlcNAcylation drive heart failure with preserved ejection fraction. H Ardehali, Y Tatekoshi, J Shapiro, M Liu, G Bianco, A Tatekoshi, ... Research Square, rs. 3. rs-2448086, 2023 | 1 | 2023 |
The Jumonji-C Histone Lysine Demethylase KDM3B Senses Cellular Iron to Regulate Anabolism Through mTORC1 J Shapiro, HC Chang, Z Zhao, J Geier, E Bartom, C Chen, Y Chen, ... | 1 | 2022 |
DNA damage and nuclear morphological changes in cardiac hypertrophy are mediated by SNRK through actin depolymerization PJ Stanczyk, Y Tatekoshi, JS Shapiro, K Nayudu, Y Chen, Z Zilber, ... Circulation 148 (20), 1582-1592, 2023 | | 2023 |
Hexokinase-1 mitochondrial dissociation and protein O-GlcNAcylation drive heart failure with preserved ejection fraction Y Tatekoshi, J Shapiro, M Liu, G Bianco, A Tatekoshi, A De Jesus, ... | | 2023 |
[WITHDRAWN] Hexokinase-1 mitochondrial dissociation and protein O-GlcNAcylation drive heart failure with preserved ejection fraction Y Tatekoshi, JS Shapiro, M Liu, GM Bianco, A Tatekoshi, A De Jesus, ... Research Square, 2023 | | 2023 |
A Novel Mechanism in the Pathogenesis of Heart Failure With Preserved Ejection Fraction Through Hexokinase Mitochondrial Dislocation and Substrate Shuttling Into the O … Y Tatekoshi, JS Shapiro, M Liu, GM Bianco, F Sharifzad, A De Jesus, ... Circulation 146 (Suppl_1), A12874-A12874, 2022 | | 2022 |
Meet the authors: Adam De Jesus and Hossein Ardehali A De Jesus Molecular Cell 82 (7), 1239-1243, 2022 | | 2022 |
HEPATOCYTE PPARGAMMA NEGATIVELY REGULATES METHIONINE METABOLISM AND CONTRIBUTES TO THE DEVELOPMENT OF NASH SM Lee, CM Pusec, A De Jesus, BT Layden, JC Chacon The Liver Meeting Digital Experience™, 2020 | | 2020 |
Role of Snf1-related Kinase as a Regulator of Chromatin Modifications and Dna-damage Response in Heart Injury PJ Stanczyk, Z Zilber, A de Jesus, HC Chang, H Ardehali Circulation Research 125 (Suppl_1), A308-A308, 2019 | | 2019 |