Tracking the evolution of non–small-cell lung cancer M Jamal-Hanjani, GA Wilson, N McGranahan, NJ Birkbak, TBK Watkins, ... New England Journal of Medicine 376 (22), 2109-2121, 2017 | 2328 | 2017 |
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1967* | 2020 |
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ... Nature 545 (7655), 446-451, 2017 | 1800 | 2017 |
Allele-specific HLA loss and immune escape in lung cancer evolution N McGranahan, R Rosenthal, CT Hiley, AJ Rowan, TBK Watkins, ... Cell 171 (6), 1259-1271. e11, 2017 | 1266 | 2017 |
The evolutionary history of 2,658 cancers M Gerstung, C Jolly, I Leshchiner, SC Dentro, S Gonzalez, D Rosebrock, ... Nature 578 (7793), 122-128, 2020 | 984 | 2020 |
The mutational landscape of normal human endometrial epithelium L Moore, D Leongamornlert, THH Coorens, MA Sanders, P Ellis, ... Nature 580 (7805), 640-646, 2020 | 438 | 2020 |
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes SC Dentro, I Leshchiner, K Haase, M Tarabichi, J Wintersinger, ... Cell 184 (8), 2239-2254. e39, 2021 | 404* | 2021 |
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition B Rodriguez-Martin, EG Alvarez, A Baez-Ortega, J Zamora, F Supek, ... Nature genetics 52 (3), 306-319, 2020 | 391 | 2020 |
Pervasive chromosomal instability and karyotype order in tumour evolution TBK Watkins, EL Lim, M Petkovic, S Elizalde, NJ Birkbak, GA Wilson, ... Nature 587 (7832), 126-132, 2020 | 319 | 2020 |
Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets DC Wedge, G Gundem, T Mitchell, DJ Woodcock, I Martincorena, M Ghori, ... Nature genetics 50 (5), 682-692, 2018 | 244 | 2018 |
Principles of reconstructing the subclonal architecture of cancers SC Dentro, DC Wedge, P Van Loo Cold Spring Harbor perspectives in medicine 7 (8), a026625, 2017 | 155 | 2017 |
Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium B Colom, MP Alcolea, G Piedrafita, MWJ Hall, A Wabik, SC Dentro, ... Nature genetics 52 (6), 604-614, 2020 | 148 | 2020 |
Mutant clones in normal epithelium outcompete and eliminate emerging tumours B Colom, A Herms, MWJ Hall, SC Dentro, C King, RK Sood, MP Alcolea, ... Nature 598 (7881), 510-514, 2021 | 139 | 2021 |
Spatial genomics maps the structure, nature and evolution of cancer clones A Lomakin, J Svedlund, C Strell, M Gataric, A Shmatko, G Rukhovich, ... Nature 611 (7936), 594-602, 2022 | 122* | 2022 |
Selection of oncogenic mutant clones in normal human skin varies with body site JC Fowler, C King, C Bryant, MWJ Hall, R Sood, SH Ong, E Earp, ... Cancer discovery 11 (2), 340-361, 2021 | 88 | 2021 |
A community effort to create standards for evaluating tumor subclonal reconstruction A Salcedo, M Tarabichi, SMG Espiritu, AG Deshwar, M David, NM Wilson, ... Nature biotechnology 38 (1), 97-107, 2020 | 75* | 2020 |
Diagnosis of Fanconi anemia: mutation analysis by next‐generation sequencing N Ameziane, D Sie, S Dentro, Y Ariyurek, L Kerkhoven, H Joenje, ... Anemia 2012 (1), 132856, 2012 | 73 | 2012 |
Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters M Linch, G Goh, C Hiley, Y Shanmugabavan, N McGranahan, A Rowan, ... Annals of Oncology 28 (10), 2472-2480, 2017 | 72 | 2017 |
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth E Abby, SC Dentro, MWJ Hall, JC Fowler, SH Ong, R Sood, A Herms, ... Nature Genetics 55 (2), 232-245, 2023 | 69 | 2023 |
Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival ND Anderson, Y Babichev, F Fuligni, F Comitani, M Layeghifard, ... Nature communications 12 (1), 4496, 2021 | 49 | 2021 |