| A deficiency in DNA repair and DNA-PKcs expression in the radiosensitive BALB/c mouse R Okayasu, K Suetomi, Y Yu, A Silver, JS Bedford, R Cox, RL Ullrich Cancer research 60 (16), 4342-4345, 2000 | 188 | 2000 |
| Repair of DNA damage induced by accelerated heavy ions in mammalian cells proficient and deficient in the non-homologous end-joining pathway R Okayasu, M Okada, A Okabe, M Noguchi, K Takakura, S Takahashi Radiation research 165 (1), 59-67, 2006 | 180 | 2006 |
| Silencing expression of the catalytic subunit of DNA-dependent protein kinase by small interfering RNA sensitizes human cells for radiation-induced chromosome damage, cell … Y Peng, Q Zhang, H Nagasawa, R Okayasu, HL Liber, JS Bedford Cancer research 62 (22), 6400-6404, 2002 | 174 | 2002 |
| Recent advances in the biology of heavy-ion cancer therapy N Hamada, T Imaoka, S Masunaga, T Ogata, R Okayasu, A Takahashi, ... Journal of radiation research 51 (4), 365-383, 2010 | 168 | 2010 |
| Contributions of direct and indirect actions in cell killing by high-LET radiations R Hirayama, A Ito, M Tomita, T Tsukada, F Yatagai, M Noguchi, ... Radiation research 171 (2), 212-218, 2009 | 167 | 2009 |
| Repair of DNA damage induced by accelerated heavy ions—a mini review R Okayasu International journal of cancer 130 (5), 991-1000, 2012 | 156 | 2012 |
| Elevated breast cancer risk in irradiated BALB/c mice associates with unique functional polymorphism of the Prkdc (DNA-dependent protein kinase catalytic subunit) gene Y Yu, R Okayasu, MM Weil, A Silver, M McCarthy, R Zabriskie, S Long, ... Cancer research 61 (5), 1820-1824, 2001 | 154 | 2001 |
| Effects of carbon ion beam on putative colon cancer stem cells and its comparison with X-rays X Cui, K Oonishi, H Tsujii, T Yasuda, Y Matsumoto, Y Furusawa, M Akashi, ... Cancer research 71 (10), 3676-3687, 2011 | 145 | 2011 |
| Inhibition of homologous recombination repair in irradiated tumor cells pretreated with Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin M Noguchi, D Yu, R Hirayama, Y Ninomiya, E Sekine, N Kubota, K Ando, ... Biochemical and biophysical research communications 351 (3), 658-663, 2006 | 139 | 2006 |
| Defective repair of DNA double-strand breaks and chromosome damage in fibroblasts from a radiosensitive leukemia patient C Badie, G Iliakis, N Foray, G Alsbeih, GE Pantellias, R Okayasu, ... Cancer research 55 (6), 1232-1234, 1995 | 119 | 1995 |
| Mechanism of radiosensitization by halogenated pyrimidines: effect of BrdU on radiation induction of DNA and chromosome damage and its correlation with cell killing G Iliakis, S Kurtzman, G Pantelias, R Okayasu Radiation research 119 (2), 286-304, 1989 | 108 | 1989 |
| The complexity of DNA double strand breaks is a critical factor enhancing end-resection H Yajima, H Fujisawa, NI Nakajima, H Hirakawa, PA Jeggo, R Okayasu, ... DNA repair 12 (11), 936-946, 2013 | 99 | 2013 |
| Linear DNA elution dose response curves obtained in CHO cells with non-unwinding filter elution after appropriate selection of the lysis conditions R Okayasu, G Iliakis International Journal of Radiation Biology 55 (4), 569-581, 1989 | 95 | 1989 |
| Metabolism and the paradoxical effects of arsenic: carcinogenesis and anticancer X Cui, Y Kobayashi, M Akashi, R Okayasu Current medicinal chemistry 15 (22), 2293-2304, 2008 | 91 | 2008 |
| Visualisation of γH2AX foci caused by heavy ion particle traversal; distinction between core track versus non-track damage NI Nakajima, H Brunton, R Watanabe, A Shrikhande, R Hirayama, ... PloS one 8 (8), e70107, 2013 | 90 | 2013 |
| Roles of the Major, Small, Acid-Soluble Spore Proteins and Spore-Specific and Universal DNA Repair Mechanisms in Resistance of Bacillus subtilis Spores to … R Moeller, P Setlow, G Horneck, T Berger, G Reitz, P Rettberg, AJ Doherty, ... Journal of bacteriology 190 (3), 1134-1140, 2008 | 89 | 2008 |
| Resistance of Bacillus subtilis spore DNA to lethal ionizing radiation damage relies primarily on spore core components and DNA repair, with minor effects of oxygen radical … R Moeller, M Raguse, G Reitz, R Okayasu, Z Li, S Klein, P Setlow, ... Applied and Environmental Microbiology 80 (1), 104-109, 2014 | 86 | 2014 |
| Wortmannin inhibits repair of DNA double-strand breaks in irradiated normal human cells R Okayasu, K Suetomi, RL Ullrich Radiation research 149 (5), 440-445, 1998 | 83 | 1998 |
| Radiosensitivity throughout the cell cycle and repair of potentially lethal damage and DNA double-strand breaks in an X-ray-sensitive CHO mutant GE Iliakis, R Okayasu International journal of radiation biology 57 (6), 1195-1211, 1990 | 82 | 1990 |
| Variation through the cell cycle in the dose-response of DNA neutral filter elution in X-irradiated synchronous CHO-cells R Okayasu, D Bloecher, G Iliakis International Journal of Radiation Biology 53 (5), 729-747, 1988 | 79 | 1988 |
John B. LittleProfessor HarvardVerified email at hsph.harvard.edu
