Ryuichi Okayasu
Ryuichi Okayasu
QST/National Institute of Radiological Sciences
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A deficiency in DNA repair and DNA-PKcs expression in the radiosensitive BALB/c mouse
R Okayasu, K Suetomi, Y Yu, A Silver, JS Bedford, R Cox, RL Ullrich
Cancer research 60 (16), 4342-4345, 2000
Silencing expression of the catalytic subunit of DNA-dependent protein kinase by small interfering RNA sensitizes human cells for radiation-induced chromosome damage, cell …
Y Peng, Q Zhang, H Nagasawa, R Okayasu, HL Liber, JS Bedford
Cancer research 62 (22), 6400-6404, 2002
Repair of DNA damage induced by accelerated heavy ions in mammalian cells proficient and deficient in the non-homologous end-joining pathway
R Okayasu, M Okada, A Okabe, M Noguchi, K Takakura, S Takahashi
Radiation research 165 (1), 59-67, 2006
Recent advances in the biology of heavy-ion cancer therapy
N Hamada, T Imaoka, S Masunaga, T Ogata, R Okayasu, A Takahashi, ...
Journal of radiation research 51 (4), 365-383, 2010
Contributions of direct and indirect actions in cell killing by high-LET radiations
R Hirayama, A Ito, M Tomita, T Tsukada, F Yatagai, M Noguchi, ...
Radiation research 171 (2), 212-218, 2009
Repair of DNA damage induced by accelerated heavy ions—a mini review
R Okayasu
International journal of cancer 130 (5), 991-1000, 2012
Elevated breast cancer risk in irradiated BALB/c mice associates with unique functional polymorphism of the Prkdc (DNA-dependent protein kinase catalytic subunit) gene
Y Yu, R Okayasu, MM Weil, A Silver, M McCarthy, R Zabriskie, S Long, ...
Cancer research 61 (5), 1820-1824, 2001
Effects of Carbon Ion Beam on Putative Colon Cancer Stem Cells and Its Comparison with X-raysHeavy-Ion Irradiation Disrupts Cancer Stem Cells
X Cui, K Oonishi, H Tsujii, T Yasuda, Y Matsumoto, Y Furusawa, M Akashi, ...
Cancer research 71 (10), 3676-3687, 2011
Inhibition of homologous recombination repair in irradiated tumor cells pretreated with Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin
M Noguchi, D Yu, R Hirayama, Y Ninomiya, E Sekine, N Kubota, K Ando, ...
Biochemical and biophysical research communications 351 (3), 658-663, 2006
Defective repair of DNA double-strand breaks and chromosome damage in fibroblasts from a radiosensitive leukemia patient
C Badie, G Iliakis, N Foray, G Alsbeih, GE Pantellias, R Okayasu, ...
Cancer research 55 (6), 1232-1234, 1995
Mechanism of radiosensitization by halogenated pyrimidines: effect of BrdU on radiation induction of DNA and chromosome damage and its correlation with cell killing
G Iliakis, S Kurtzman, G Pantelias, R Okayasu
Radiation research 119 (2), 286-304, 1989
Linear DNA elution dose response curves obtained in CHO cells with non-unwinding filter elution after appropriate selection of the lysis conditions
R Okayasu, G Iliakis
International Journal of Radiation Biology 55 (4), 569-581, 1989
The complexity of DNA double strand breaks is a critical factor enhancing end-resection
H Yajima, H Fujisawa, NI Nakajima, H Hirakawa, PA Jeggo, R Okayasu, ...
DNA repair 12 (11), 936-946, 2013
Metabolism and the paradoxical effects of arsenic: carcinogenesis and anticancer
X Cui, Y Kobayashi, M Akashi, R Okayasu
Current medicinal chemistry 15 (22), 2293-2304, 2008
Visualisation of γH2AX foci caused by heavy ion particle traversal; distinction between core track versus non-track damage
NI Nakajima, H Brunton, R Watanabe, A Shrikhande, R Hirayama, ...
PloS one 8 (8), e70107, 2013
Roles of the Major, Small, Acid-Soluble Spore Proteins and Spore-Specific and Universal DNA Repair Mechanisms in Resistance of Bacillus subtilis Spores to …
R Moeller, P Setlow, G Horneck, T Berger, G Reitz, P Rettberg, AJ Doherty, ...
Journal of bacteriology 190 (3), 1134-1140, 2008
Wortmannin inhibits repair of DNA double-strand breaks in irradiated normal human cells
R Okayasu, K Suetomi, RL Ullrich
Radiation research 149 (5), 440-445, 1998
Variation through the cell cycle in the dose-response of DNA neutral filter elution in X-irradiated synchronous CHO-cells
R Okayasu, D Bloecher, G Iliakis
International Journal of Radiation Biology 53 (5), 729-747, 1988
Resistance of Bacillus subtilis spore DNA to lethal ionizing radiation damage relies primarily on spore core components and DNA repair, with minor effects of oxygen radical …
R Moeller, M Raguse, G Reitz, R Okayasu, Z Li, S Klein, P Setlow, ...
Applied and Environmental Microbiology 80 (1), 104-109, 2014
Radiosensitivity throughout the cell cycle and repair of potentially lethal damage and DNA double-strand breaks in an X-ray-sensitive CHO mutant
GE Iliakis, R Okayasu
International journal of radiation biology 57 (6), 1195-1211, 1990
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