Genomic subtypes of non-invasive bladder cancer with distinct metabolic profile and female gender bias in KDM6A mutation frequency CD Hurst, O Alder, FM Platt, A Droop, LF Stead, JE Burns, GJ Burghel, ... Cancer cell 32 (5), 701-715. e7, 2017 | 270 | 2017 |
Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions R Birnie, SD Bryce, C Roome, V Dussupt, A Droop, SH Lang, PA Berry, ... Genome biology 9, 1-13, 2008 | 268 | 2008 |
Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa A Buskin, L Zhu, V Chichagova, B Basu, S Mozaffari-Jovin, D Dolan, ... Nature communications 9 (1), 4234, 2018 | 178 | 2018 |
The mutational signature profile of known and suspected human carcinogens in mice L Riva, AR Pandiri, YR Li, A Droop, J Hewinson, MA Quail, V Iyer, ... Nature genetics 52 (11), 1189-1197, 2020 | 96 | 2020 |
β-Catenin–mediated immune evasion pathway frequently operates in primary cutaneous melanomas J Nsengimana, J Laye, A Filia, S O’Shea, S Muralidhar, J Poźniak, ... The Journal of clinical investigation 128 (5), 2048-2063, 2018 | 86 | 2018 |
Combinatorial CRISPR screen identifies fitness effects of gene paralogues NA Thompson, M Ranzani, L van der Weyden, V Iyer, V Offord, A Droop, ... Nature communications 12 (1), 1302, 2021 | 72 | 2021 |
Prediction of clinical outcome in glioblastoma using a biologically relevant nine-microRNA signature J Hayes, H Thygesen, C Tumilson, A Droop, M Boissinot, TA Hughes, ... Molecular oncology 9 (3), 704-714, 2015 | 68 | 2015 |
KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice ES Polson, VB Kuchler, C Abbosh, EM Ross, RK Mathew, HA Beard, ... Science translational medicine 10 (454), eaar2718, 2018 | 67 | 2018 |
Loss of CSL unlocks a hypoxic response and enhanced tumor growth potential in breast cancer cells EB Braune, YL Tsoi, YP Phoon, S Landor, HS Cascales, D Ramsköld, ... Stem cell reports 6 (5), 643-651, 2016 | 64* | 2016 |
Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma HJ Close, LF Stead, J Nsengimana, KA Reilly, A Droop, H Wurdak, ... Clinical & Experimental Immunology 200 (1), 33-44, 2020 | 61 | 2020 |
Genetic and environmental determinants of immune response to cutaneous melanoma J Poźniak, J Nsengimana, JP Laye, SJ O’Shea, JMS Diaz, AP Droop, ... Cancer research 79 (10), 2684-2696, 2019 | 54 | 2019 |
Elucidating drivers of oral epithelial dysplasia formation and malignant transformation to cancer using RNAseq C Conway, JL Graham, P Chengot, C Daly, R Chalkley, L Ross, A Droop, ... Oncotarget 6 (37), 40186, 2015 | 42 | 2015 |
Retinoic acid and androgen receptors combine to achieve tissue specific control of human prostatic transglutaminase expression: a novel regulatory network with broader significance GC Rivera-Gonzalez, AP Droop, HJ Rippon, K Tiemann, D Pellacani, ... Nucleic acids research 40 (11), 4825-4840, 2012 | 40 | 2012 |
Engineering Simulations as Scientific Instruments: A Pattern Language: With Kieran Alden, Paul S. Andrews, James L. Bown, Alastair Droop, Richard B. Greaves, Mark Read, Adam T … S Stepney, FAC Polack Springer, 2018 | 37 | 2018 |
DNA hypermethylation in prostate cancer is a consequence of aberrant epithelial differentiation and hyperproliferation D Pellacani, D Kestoras, AP Droop, FM Frame, PA Berry, MG Lawrence, ... Cell Death & Differentiation 21 (5), 761-773, 2014 | 37 | 2014 |
The calcium sensor STIM1 is regulated by androgens in prostate stromal cells PA Berry, R Birnie, AP Droop, NJ Maitland, AT Collins The Prostate 71 (15), 1646-1655, 2011 | 33 | 2011 |
fqtools: an efficient software suite for modern FASTQ file manipulation AP Droop Bioinformatics 32 (12), 1883-1884, 2016 | 29 | 2016 |
Differential CpG DNA methylation in peripheral naïve CD4+ T-cells in early rheumatoid arthritis patients R Pitaksalee, AN Burska, S Ajaib, J Rogers, R Parmar, K Mydlova, X Xie, ... Clinical epigenetics 12, 1-16, 2020 | 28 | 2020 |
Hematopoietic Stem Cell Gene Therapy for Brain Metastases Using Myeloid Cell–Specific Gene Promoters T Andreou, N Rippaus, K Wronski, J Williams, D Taggart, S Cherqui, ... JNCI: Journal of the National Cancer Institute 112 (6), 617-627, 2020 | 20 | 2020 |
A case-matched gender comparison transcriptomic screen identifies eIF4E and eIF5 as potential prognostic markers in male breast cancer MP Humphries, S Sundara Rajan, A Droop, CAB Suleman, C Carbone, ... Clinical Cancer Research 23 (10), 2575-2583, 2017 | 19 | 2017 |