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Sascha Young Kupke
Sascha Young Kupke
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Title
Cited by
Cited by
Year
Single-cell analysis and stochastic modelling unveil large cell-to-cell variability in influenza A virus infection
FS Heldt, SY Kupke, S Dorl, U Reichl, T Frensing
Nature communications 6 (1), 8938, 2015
1482015
Influenza virus intracellular replication dynamics, release kinetics, and particle morphology during propagation in MDCK cells
T Frensing, SY Kupke, M Bachmann, S Fritzsche, LE Gallo-Ramirez, ...
Applied microbiology and biotechnology 100, 7181-7192, 2016
762016
A novel type of influenza A virus-derived defective interfering particle with nucleotide substitutions in its genome
SY Kupke, D Riedel, T Frensing, P Zmora, U Reichl
Journal of Virology 93 (4), 10.1128/jvi. 01786-18, 2019
412019
Multiscale modeling of influenza A virus replication in cell cultures predicts infection dynamics for highly different infection conditions
D Rüdiger, SY Kupke, T Laske, P Zmora, U Reichl
PLOS Computational Biology 15 (2), e1006819, 2019
342019
Cell culture–based production of defective interfering influenza A virus particles in perfusion mode using an alternating tangential flow filtration system
MD Hein, A Chawla, M Cattaneo, SY Kupke, Y Genzel, U Reichl
Applied microbiology and biotechnology 105, 7251-7264, 2021
252021
OP7, a novel influenza A virus defective interfering particle: production, purification, and animal experiments demonstrating antiviral potential
MD Hein, H Kollmus, P Marichal-Gallardo, S Püttker, D Benndorf, ...
Applied microbiology and biotechnology 105, 129-146, 2021
242021
Antiviral activity of influenza A virus defective interfering particles against SARS-CoV-2 replication in vitro through stimulation of innate immunity
U Rand, SY Kupke, H Shkarlet, MD Hein, T Hirsch, P Marichal-Gallardo, ...
Cells 10 (7), 1756, 2021
222021
Semi-continuous propagation of influenza A virus and its defective interfering particles: analyzing the dynamic competition to select candidates for antiviral therapy
L Pelz, D Rüdiger, T Dogra, FG Alnaji, Y Genzel, CB Brooke, SY Kupke, ...
Journal of Virology 95 (24), 10.1128/jvi. 01174-21, 2021
212021
Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles
MD Hein, P Arora, P Marichal-Gallardo, M Winkler, Y Genzel, S Pöhlmann, ...
BMC biology 19 (1), 91, 2021
202021
Single-cell analysis uncovers a vast diversity in intracellular viral defective interfering RNA content affecting the large cell-to-cell heterogeneity in influenza A virus …
SY Kupke, LH Ly, ST Börno, A Ruff, B Timmermann, M Vingron, S Haas, ...
Viruses 12 (1), 71, 2020
192020
Multiscale model of defective interfering particle replication for influenza A virus infection in animal cell culture
D Rüdiger, L Pelz, MD Hein, SY Kupke, U Reichl
PLoS Computational Biology 17 (9), e1009357, 2021
92021
Single-cell analysis and stochastic modelling unveil large cell-to-cell variability in influenza A virus infection. Nat Commun. 2015; 6: 8938
FS Heldt, SY Kupke, S Dorl, U Reichl, T Frensing
Epub 2015/11/21. https://doi. org/10.1038/ncomms9938 PMID: 26586423, 0
9
Absolute quantification of viral proteins during single-round replication of MDCK suspension cells
J Küchler, S Püttker, P Lahmann, Y Genzel, S Kupke, D Benndorf, ...
Journal of Proteomics 259, 104544, 2022
52022
Broad-spectrum antiviral activity of Influenza A defective interfering particles against respiratory syncytial, Yellow Fever, and Zika Virus replication in vitro
L Pelz, E Piagnani, P Marsall, N Wynserski, MD Hein, P Marichal-Gallardo, ...
Viruses 15 (9), 1872, 2023
32023
Generation of “OP7 chimera” defective interfering influenza A particle preparations free of infectious virus that show antiviral efficacy in mice
T Dogra, L Pelz, JD Boehme, J Kuechler, O Kershaw, P Marichal-Gallardo, ...
Scientific Reports 13 (1), 20936, 2023
22023
Production of retroviral vectors in continuous high cell density culture
MD Hein, D Kazenmaier, Y van Heuvel, T Dogra, M Cattaneo, SY Kupke, ...
Applied Microbiology and Biotechnology 107 (19), 5947-5961, 2023
22023
Antiviral activity of influenza A virus defective interfering particles against SARS-CoV-2 replication in vitro through stimulation of innate immunity. Cells. 2021; 10 (7): 1756
U Rand, SY Kupke, H Shkarlet, MD Hein, T Hirsch, P Marichal-Gallardo, ...
s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021
12021
Production of antiviral “OP7 chimera” defective interfering particles free of infectious virus
L Pelz, T Dogra, P Marichal-Gallardo, MD Hein, G Hemissi, SY Kupke, ...
Applied Microbiology and Biotechnology 108 (1), 1-15, 2024
2024
Mathematical model calibrated to in vitro data predicts mechanisms of antiviral action of the influenza defective interfering particle “OP7”
D Rüdiger, J Piasecka, J Küchler, C Pontes, T Laske, SY Kupke, U Reichl
iScience, 2024
2024
Influenza A virus defective interfering particles as antiviral agents
SY Kupke, T Dogra, L Pelz, MD Hein, N Ndeir, U Rand, J Boehme, ...
32 nd Annual Meeting of the Society for Virology (GfV), 2023
2023
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