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Sascha Young Kupke
Sascha Young Kupke
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Title
Cited by
Cited by
Year
Single-cell analysis and stochastic modelling unveil large cell-to-cell variability in influenza A virus infection
FS Heldt, SY Kupke, S Dorl, U Reichl, T Frensing
Nature communications 6 (1), 8938, 2015
1352015
Influenza virus intracellular replication dynamics, release kinetics, and particle morphology during propagation in MDCK cells
T Frensing, SY Kupke, M Bachmann, S Fritzsche, LE Gallo-Ramirez, ...
Applied microbiology and biotechnology 100, 7181-7192, 2016
692016
A novel type of influenza A virus-derived defective interfering particle with nucleotide substitutions in its genome
SY Kupke, D Riedel, T Frensing, P Zmora, U Reichl
Journal of Virology 93 (4), e01786-18, 2019
352019
Multiscale modeling of influenza A virus replication in cell cultures predicts infection dynamics for highly different infection conditions
D Rüdiger, SY Kupke, T Laske, P Zmora, U Reichl
PLOS Computational Biology 15 (2), e1006819, 2019
292019
OP7, a novel influenza A virus defective interfering particle: production, purification, and animal experiments demonstrating antiviral potential
MD Hein, H Kollmus, P Marichal-Gallardo, S Püttker, D Benndorf, ...
Applied microbiology and biotechnology 105, 129-146, 2021
182021
Antiviral activity of influenza A virus defective interfering particles against SARS-CoV-2 replication in vitro through stimulation of innate immunity
U Rand, SY Kupke, H Shkarlet, MD Hein, T Hirsch, P Marichal-Gallardo, ...
Cells 10 (7), 1756, 2021
162021
Semi-continuous propagation of influenza A virus and its defective interfering particles: analyzing the dynamic competition to select candidates for antiviral therapy
L Pelz, D Rüdiger, T Dogra, FG Alnaji, Y Genzel, CB Brooke, SY Kupke, ...
Journal of virology 95 (24), e01174-21, 2021
152021
Single-cell analysis uncovers a vast diversity in intracellular viral defective interfering RNA content affecting the large cell-to-cell heterogeneity in influenza A virus …
SY Kupke, LH Ly, ST Börno, A Ruff, B Timmermann, M Vingron, S Haas, ...
Viruses 12 (1), 71, 2020
142020
Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles
MD Hein, P Arora, P Marichal-Gallardo, M Winkler, Y Genzel, S Pöhlmann, ...
BMC biology 19 (1), 1-18, 2021
122021
Cell culture–based production of defective interfering influenza A virus particles in perfusion mode using an alternating tangential flow filtration system
MD Hein, A Chawla, M Cattaneo, SY Kupke, Y Genzel, U Reichl
Applied Microbiology and Biotechnology 105, 7251-7264, 2021
122021
Single-cell analysis and stochastic modelling unveil large cell-to-cell variability in influenza A virus infection. Nat Commun. 2015; 6: 8938
FS Heldt, SY Kupke, S Dorl, U Reichl, T Frensing
Epub 2015/11/21. https://doi. org/10.1038/ncomms9938 PMID: 26586423, 0
8
Multiscale model of defective interfering particle replication for influenza A virus infection in animal cell culture
D Rüdiger, L Pelz, MD Hein, SY Kupke, U Reichl
PLoS Computational Biology 17 (9), e1009357, 2021
42021
Absolute quantification of viral proteins during single-round replication of MDCK suspension cells
J Küchler, S Püttker, P Lahmann, Y Genzel, S Kupke, D Benndorf, ...
Journal of Proteomics 259, 104544, 2022
22022
Antiviral activity of influenza A virus defective interfering particles against SARS-CoV-2 replication in vitro through stimulation of innate immunity. Cells. 2021; 10 (7): 1756
U Rand, SY Kupke, H Shkarlet, MD Hein, T Hirsch, P Marichal-Gallardo, ...
s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021
12021
Protective interfering nucleic acid molecule and virus-like particle, viral vector, or virus particle containing the same as well as pharmaceutical composition containing the …
S Kupke, T Frensing, P Zmora, U Reichl
US Patent 11,274,304, 2022
2022
Influenza A Virus-Derived Defective Interfering Particles for Antiviral Treatment
M Hein, T Dogra, P Arora, U Rand, Y Genzel, M Cattaneo, M Winkler, ...
27th ESACT Meeting, 2022
2022
Modeling the intracellular replication of a new type of defective interfering particle of influenza virus with genomic nucleotide substitutions
D Rüdiger, J Küchler, C Pontes, SY Kupke, U Reichl
12th European Conference on Mathematical and Theoretical Biology, 2022
2022
Reverse genetics for Influenza A virus to generate genetically engineered defective interfering particles for antiviral treatment and vaccination
T Dogra, L Pelz, H Marc, D Rüdiger, J Boehme, D Bruder, SY Kupke, ...
27th ESACT Meeting, 2022
2022
Influenza A virus-derived defective interfering particles for antiviral treatment
SY Kupke, MD Hein, Y Genzel, L Pelz, P Marichal-Gallardo, N Bdeir, ...
2022
Long-term propagation of influenza A virus and its defective interfering particles: Analyzing dynamic competition to select antiviral candidates
L Pelz, D Rüdiger, T Dogra, FG Alnaji, Y Genzel, CB Brooke, SY Kupke, ...
2022
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