Katharina Mahal
Katharina Mahal
Cancer Research UK Manchester Institute
Verified email at - Homepage
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Gold (I)–NHC complexes of antitumoral diarylimidazoles: Structures, cellular uptake routes and anticancer activities
L Kaps, B Biersack, H Müller-Bunz, K Mahal, J Münzner, M Tacke, ...
Journal of inorganic biochemistry 106 (1), 52-58, 2012
Effects of chrysin, apigenin, genistein and their homoleptic copper (II) complexes on the growth and metastatic potential of cancer cells
C Spoerlein, K Mahal, H Schmidt, R Schobert
Journal of inorganic biochemistry 127, 107-115, 2013
Ferrocene and (arene) ruthenium (II) complexes of the natural anticancer naphthoquinone plumbagin with enhanced efficacy against resistant cancer cells and a genuine mode of action
C Spoerlein-Guettler, K Mahal, R Schobert, B Biersack
Journal of inorganic biochemistry 138, 64-72, 2014
Cancer selective metallocenedicarboxylates of the fungal cytotoxin Illudin M
R Schobert, S Seibt, K Mahal, A Ahmad, B Biersack, ...
Journal of medicinal chemistry 54 (18), 6177-6182, 2011
Combretastatin A-4 derived 5-(1-methyl-4-phenyl-imidazol-5-yl) indoles with superior cytotoxic and anti-vascular effects on chemoresistant cancer cells and tumors
K Mahal, B Biersack, S Schruefer, M Resch, R Ficner, R Schobert, ...
European Journal of Medicinal Chemistry 118, 9-20, 2016
Improved anticancer and antiparasitic activity of new lawsone Mannich bases
K Mahal, A Ahmad, F Schmitt, J Lockhauserbńumer, K Starz, R Pradhan, ...
European journal of medicinal chemistry 126, 421-431, 2017
Effects of the Tumor‐Vasculature‐Disrupting Agent Verubulin and Two Heteroaryl Analogues on Cancer Cells, Endothelial Cells, and Blood Vessels
K Mahal, M Resch, R Ficner, R Schobert, B Biersack, T Mueller
ChemMedChem 9 (4), 847-854, 2014
New ferrocene modified lawsone Mannich bases with anti-proliferative activity against tumor cells
A Ahmad, K Mahal, S Padhye, FH Sarkar, R Schobert, B Biersack
Journal of Saudi Chemical Society 21 (1), 105-110, 2017
Combretastatin A-4 derived imidazoles show cytotoxic, antivascular, and antimetastatic effects based on cytoskeletal reorganisation
K Mahal, B Biersack, H Caysa, R Schobert, T Mueller
Investigational new drugs 33 (3), 541-554, 2015
Cellular Localisation of Antitumoral 6‐Alkyl Thymoquinones Revealed by an Alkyne–Azide Click Reaction and the Streptavidin–Biotin System
K Effenberger‐Neidnicht, S Breyer, K Mahal, R Diestel, F Sasse, ...
ChemBioChem 12 (8), 1237-1241, 2011
Biological evaluation of 4, 5-diarylimidazoles with hydroxamic acid appendages as novel dual mode anticancer agents
K Mahal, S Schruefer, G Steinemann, F Rausch, R Schobert, B Biersack, ...
Cancer chemotherapy and pharmacology 75 (4), 691-700, 2015
4-(1-Ethyl-4-anisyl-imidazol-5-yl)-N-hydroxycinnamide–A new pleiotropic HDAC inhibitor targeting cancer cell signalling and cytoskeletal organisation
K Mahal, P Kahlen, B Biersack, R Schobert
Experimental cell research 336 (2), 263-275, 2015
New Oxazole-bridged combretastatin A-4 analogues as potential vascular-disrupting agents
K Mahal, B Biersack, R Schobert
Int. J. Clin. Pharmacol. Ther 51, 41-43, 2013
Role of JNK and NF-κB in mediating the effect of combretastatin A-4 and brimamin on endothelial and carcinoma cells
K Mahal, A Ahmad, S Sethi, M Resch, R Ficner, FH Sarkar, R Schobert, ...
Cellular Oncology 38 (6), 463-478, 2015
Modification of uptake and subcellular distribution of doxorubicin by N-acylhydrazone residues as visualised by intrinsic fluorescence
K Effenberger-Neidnicht, S Breyer, K Mahal, F Sasse, R Schobert
Cancer chemotherapy and pharmacology 69 (1), 85-90, 2012
4, 5-Diarylimidazole derivatives as HDAC inhibitors
M Höpfner, B Biersack, R Schobert, K Mahal
US Patent 9,868,750, 2018
EACR-MRS conference on Seed and Soil: In Vivo Models of Metastasis
IT Alves, N Cohen, PG Ersan, R Eyre, I Godet, D Holovanchuk, ...
Clinical & experimental metastasis 34 (8), 449-456, 2017
UM Cure 2020: New therapies for uveal melanoma
S Roman-Roman, MH Stern, S Alsafadi, MJ Jager, M Dogrusöz, ...
Impact 2018 (2), 15-17, 2018
CRISPR-generated BAP1 knockdown in uveal melanoma cell lines affects organotropism
K Mahal, K Brooks, A Mandal, M Smith, N Dhomen, R Marais
Cancer Research 77 (13 Supplement), 4844-4844, 2017
A mechanistic assessment of novel anticancer drugs targeting the metastatic cascade and tumour vascularisation.
K Mahal
Dissertation, Bayreuth, Universität Bayreuth, 2015, 2015
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