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Matthew Kutys
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A non-canonical Notch complex regulates adherens junctions and vascular barrier function
WJ Polacheck*, ML Kutys*, J Yang, J Eyckmans, Y Wu, H Vasavada, ...
Nature 552 (7684), 258, 2017
3022017
Dimensions in cell migration
AD Doyle, RJ Petrie, ML Kutys, KM Yamada
Current opinion in cell biology 25 (5), 642-649, 2013
2472013
Microfabricated blood vessels for modeling the vascular transport barrier
WJ Polacheck, ML Kutys, JB Tefft, CS Chen
Nature protocols 14 (5), 1425-1454, 2019
1532019
Micro-environmental control of cell migration–myosin IIA is required for efficient migration in fibrillar environments through control of cell adhesion dynamics
AD Doyle, ML Kutys, MA Conti, K Matsumoto, RS Adelstein, KM Yamada
Journal of cell science 125 (9), 2244-2256, 2012
1442012
Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions
A Chopra*, ML Kutys*, K Zhang*, WJ Polacheck, CC Sheng, RJ Luu, ...
Developmental cell 44 (1), 87-96. e5, 2018
1422018
Extracellular matrix alignment dictates the organization of focal adhesions and directs uniaxial cell migration
WY Wang, AT Pearson, ML Kutys, CK Choi, MA Wozniak, BM Baker, ...
APL bioengineering 2 (4), 2018
992018
An extracellular-matrix-specific GEF–GAP interaction regulates Rho GTPase crosstalk for 3D collagen migration
ML Kutys, KM Yamada
Nature cell biology 16 (9), 909-917, 2014
972014
3D mesenchymal cell migration is driven by anterior cellular contraction that generates an extracellular matrix prestrain
AD Doyle, DJ Sykora, GG Pacheco, ML Kutys, KM Yamada
Developmental cell 56 (6), 826-841. e4, 2021
752021
Regulation of cell adhesion and migration by cell-derived matrices
ML Kutys, AD Doyle, KM Yamada
Experimental cell research 319 (16), 2434-2439, 2013
742013
Ubiquitylation of phosphatidylinositol 4-phosphate 5-kinase type I γ by HECTD1 regulates focal adhesion dynamics and cell migration
X Li, Q Zhou, M Sunkara, ML Kutys, Z Wu, P Rychahou, AJ Morris, H Zhu, ...
Journal of cell science 126 (12), 2617-2628, 2013
732013
Forces and mechanotransduction in 3D vascular biology
ML Kutys, CS Chen
Current opinion in cell biology 42, 73-79, 2016
662016
Monte Carlo analysis of neck linker extension in kinesin molecular motors
ML Kutys, J Fricks, WO Hancock
PLoS computational biology 6 (11), e1000980, 2010
432010
Uncovering mutation-specific morphogenic phenotypes and paracrine-mediated vessel dysfunction in a biomimetic vascularized mammary duct platform
ML Kutys, WJ Polacheck, MK Welch, KA Gagnon, T Koorman, S Kim, L Li, ...
Nature communications 11 (1), 3377, 2020
292020
Rho GEFs and GAPs: emerging integrators of extracellular matrix signaling
ML Kutys, KM Yamada
Small GTPases 6 (1), 16-19, 2015
202015
Adherens junctions organize size-selective proteolytic hotspots critical for Notch signalling
M Kwak, KM Southard, WR Kim, A Lin, NH Kim, R Gopalappa, HJ Lee, ...
Nature cell biology 24 (12), 1739-1753, 2022
92022
Microphysiological model of PIK3CA-driven vascular malformations reveals a role of dysregulated Rac1 and mTORC1/2 in lesion formation
WY Aw, C Cho, H Wang, AH Cooper, EL Doherty, D Rocco, SA Huang, ...
Science advances 9 (7), eade8939, 2023
82023
A convolutional neural network STIFMap reveals associations between stromal stiffness and EMT in breast cancer
C Stashko, MK Hayward, JJ Northey, N Pearson, AJ Ironside, JN Lakins, ...
Nature communications 14 (1), 3561, 2023
52023
Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation
FR Adler, ARA Anderson, A Bhushan, P Bogdan, JJ Bravo-Cordero, ...
Cell systems 14 (4), 252-257, 2023
42023
Conversation before crossing: dissecting metastatic tumor-vascular interactions in microphysiological systems
LN Mayo, ML Kutys
American Journal of Physiology-Cell Physiology 323 (5), C1333-C1344, 2022
32022
35 challenges in materials science being tackled by PIs under 35 (ish) in 2021
B Aguado, LJ Bray, S Caneva, JP Correa-Baena, G Di Martino, C Fang, ...
Matter 4 (12), 3804-3810, 2021
22021
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