Roman Fischer
Roman Fischer
Discovery Proteomics Facility, University of Oxford
Verified email at - Homepage
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Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling
J Adam, E Hatipoglu, L O'Flaherty, N Ternette, N Sahgal, H Lockstone, ...
Cancer cell 20 (4), 524-537, 2011
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
EL Mills, DG Ryan, HA Prag, D Dikovskaya, D Menon, Z Zaslona, ...
Nature 556 (7699), 113-117, 2018
Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes
M Altun, HB Kramer, LI Willems, JL McDermott, CA Leach, SJ Goldenberg, ...
Chemistry & biology 18 (11), 1401-1412, 2011
Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming
G Kochan, T Krojer, D Harvey, R Fischer, L Chen, M Vollmar, F von Delft, ...
Proceedings of the National Academy of Sciences 108 (19), 7745-7750, 2011
Ancient proteins resolve the evolutionary history of Darwin’s South American ungulates
F Welker, MJ Collins, JA Thomas, M Wadsley, S Brace, E Cappellini, ...
Nature 522 (7554), 81-84, 2015
Palaeoproteomic evidence identifies archaic hominins associated with the Châtelperronian at the Grotte du Renne
F Welker, M Hajdinjak, S Talamo, K Jaouen, M Dannemann, F David, ...
Proceedings of the National Academy of Sciences 113 (40), 11162-11167, 2016
Comparative evaluation of label‐free SINQ normalized spectral index quantitation in the central proteomics facilities pipeline
DC Trudgian, G Ridlova, R Fischer, MM Mackeen, N Ternette, O Acuto, ...
Proteomics 11 (14), 2790-2797, 2011
Direct evidence of milk consumption from ancient human dental calculus
C Warinner, J Hendy, C Speller, E Cappellini, R Fischer, C Trachsel, ...
Scientific reports 4 (1), 1-6, 2014
Metalloprotease SPRTN/DVC1 orchestrates replication-coupled DNA-protein crosslink repair
B Vaz, M Popovic, JA Newman, J Fielden, H Aitkenhead, S Halder, ...
Molecular cell 64 (4), 704-719, 2016
Inhibition of mitochondrial aconitase by succination in fumarate hydratase deficiency
N Ternette, M Yang, M Laroyia, M Kitagawa, L O’Flaherty, K Wolhulter, ...
Cell reports 3 (3), 689-700, 2013
Protein sequences bound to mineral surfaces persist into deep time
B Demarchi, S Hall, T Roncal-Herrero, CL Freeman, J Woolley, MK Crisp, ...
elife 5, e17092, 2016
A late middle pleistocene denisovan mandible from the tibetan plateau
F Chen, F Welker, CC Shen, SE Bailey, I Bergmann, S Davis, H Xia, ...
Nature 569 (7756), 409-412, 2019
53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ
H Ghezraoui, C Oliveira, JR Becker, K Bilham, D Moralli, C Anzilotti, ...
Nature 560 (7716), 122-127, 2018
Detection of multiple autoantibodies in patients with ankylosing spondylitis using nucleic acid programmable protein arrays
C Wright, S Sibani, D Trudgian, R Fischer, B Kessler, J LaBaer, ...
Molecular & Cellular Proteomics 11 (2), 2012
Identification of distinct circulating exosomes in Parkinson's disease
PR Tomlinson, Y Zheng, R Fischer, R Heidasch, C Gardiner, S Evetts, ...
Annals of clinical and translational neurology 2 (4), 353-361, 2015
OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation
RS Singleton, P Liu-Yi, F Formenti, W Ge, R Fischer, J Adam, PJ Pollard, ...
Proceedings of the National Academy of Sciences 111 (11), 4031-4036, 2014
Expression of citrulline and homocitrulline residues in the lungs of non-smokers and smokers: implications for autoimmunity in rheumatoid arthritis
EB Lugli, RESM Correia, R Fischer, K Lundberg, KR Bracke, ...
Arthritis research & therapy 17 (1), 9, 2015
Discovery of candidate serum proteomic and metabolomic biomarkers in ankylosing spondylitis
R Fischer, DC Trudgian, C Wright, G Thomas, LA Bradbury, MA Brown, ...
Molecular & cellular proteomics 11 (2), 2012
Gel‐aided sample preparation (GASP)—A simplified method for gel‐assisted proteomic sample generation from protein extracts and intact cells
R Fischer, BM Kessler
Proteomics 15 (7), 1224-1229, 2015
Optimal translational termination requires C4 lysyl hydroxylation of eRF1
T Feng, A Yamamoto, SE Wilkins, E Sokolova, LA Yates, M Münzel, ...
Molecular cell 53 (4), 645-654, 2014
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