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Osvaldo Andrade Santos-Filho
Osvaldo Andrade Santos-Filho
Professor of Physical Chemistry and Molecular Modeling, Federal University of Rio de Janeiro
Verified email at ippn.ufrj.br
Title
Cited by
Cited by
Year
Design, synthesis, and antiviral activity of new 1H-1, 2, 3-triazole nucleoside ribavirin analogs
M de Lourdes G Ferreira, L Pinheiro, OA Santos-Filho, MDS Peçanha, ...
Medicinal Chemistry Research 23 (3), 1501-1511, 2014
982014
Dietary flavonoids fisetin, luteolin and their derived compounds inhibit arginase, a central enzyme in Leishmania (Leishmania) amazonensis infection
LC Manjolin, MBG dos Reis, C do Carmo Maquiaveli, OA Santos-Filho, ...
Food chemistry 141 (3), 2253-2262, 2013
982013
Rational design of new antituberculosis agents: Receptor-independent four-dimensional quantitative structure− activity relationship analysis of a set of isoniazid derivatives
KFM Pasqualoto, EI Ferreira, OA Santos-Filho, AJ Hopfinger
Journal of medicinal chemistry 47 (15), 3755-3764, 2004
772004
Modelagem de proteínas por homologia
OA Santos Filho, RB Alencastro
Química Nova 26, 253-259, 2003
762003
Mapping the Protein Interaction Network in Methicillin-Resistant Staphylococcus aureus
A Cherkasov, M Hsing, R Zoraghi, LJ Foster, RH See, N Stoynov, J Jiang, ...
Journal of proteome research 10 (3), 1139-1150, 2011
712011
Inhibition of Leishmania (Leishmania) amazonensis and Rat Arginases by Green Tea EGCG, (+)-Catechin and (−)-Epicatechin: A Comparative Structural Analysis …
MBG dos Reis, LC Manjolin, CC Maquiaveli, OA Santos-Filho, ...
PLoS One 8 (11), e78387, 2013
692013
Molecular modeling of wild-type and antifolate resistant mutant Plasmodium falciparum DHFR
RT Delfino, OA Santos-Filho, JD Figueroa-Villar
Biophysical chemistry 98 (3), 287-300, 2002
652002
New Trifluoromethyl Triazolopyrimidines as Anti-Plasmodiumfalciparum Agents
N Boechat, LCS Pinheiro, TS Silva, ACC Aguiar, AS Carvalho, MM Bastos, ...
Molecules 17 (7), 8285-8302, 2012
642012
Design and Synthesis of New N-(5-Trifluoromethyl)-1H-1,2,4-triazol-3-yl Benzenesulfonamides as Possible Antimalarial Prototypes
N Boechat, LCS Pinheiro, OA Santos-Filho, IC Silva
Molecules 16 (9), 8083-8097, 2011
602011
A search for sources of drug resistance by the 4D-QSAR analysis of a set of antimalarial dihydrofolate reductase inhibitors
OA Santos-Filho, AJ Hopfinger
Journal of computer-aided molecular design 15 (1), 1-12, 2001
542001
Type 2 antifolates in the chemotherapy of falciparum malaria
RT Delfino, OA Santos-Filho, JD Figueroa-Villar
Journal of the Brazilian Chemical Society 13, 727-741, 2002
492002
An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin
A Cherkasov, F Ban, O Santos-Filho, N Thorsteinson, M Fallahi, ...
Journal of medicinal chemistry 51 (7), 2047-2056, 2008
462008
The receptor-dependent QSAR paradigm: an overview of the current state of the art
OA Santos-Filho, AJ Hopfinger, A Cherkasov, RB de Alencastro
Medicinal Chemistry 5 (4), 359-366, 2009
432009
Free energy force field (FEFF) 3D-QSAR analysis of a set of Plasmodium falciparum dihydrofolate reductase inhibitors
OA Santos-Filho, RK Mishra, AJ Hopfinger
Journal of Computer-Aided Molecular Design 15 (9), 787-810, 2001
432001
Homology modeling of wild type and pyrimethamine/cycloguanil-cross resistant mutant type Plasmodium falciparum dihydrofolate reductase. A model for antimalarial chemotherapy …
OA Santos-Filho, RB de Alencastro, JD Figueroa-Villar
Biophysical Chemistry 91 (3), 305-317, 2001
372001
Structure-based QSAR analysis of a set of 4-hydroxy-5, 6-dihydropyrones as inhibitors of HIV-1 protease: an application of the receptor-dependent (RD) 4D-QSAR formalism
OA Santos-Filho, AJ Hopfinger
Journal of chemical information and modeling 46 (1), 345-354, 2006
342006
The 4D‐QSAR Paradigm: Application to a Novel Set of Non‐peptidic HIV Protease Inhibitors
OA Santos‐Filho, AJ Hopfinger
Quantitative Structure‐Activity Relationships 21 (4), 369-381, 2002
292002
In silico identification of anthropogenic chemicals as ligands of zebrafish sex hormone binding globulin
N Thorsteinson, F Ban, O Santos-Filho, SMH Tabaei, S Miguel-Queralt, ...
Toxicology and applied pharmacology 234 (1), 47-57, 2009
282009
Aureonitol, a fungi-derived tetrahydrofuran, inhibits influenza replication by targeting its surface glycoprotein hemagglutinin
CQ Sacramento, A Marttorelli, N Fintelman-Rodrigues, CS de Freitas, ...
PLoS One 10 (10), e0139236, 2015
272015
Molecular modeling of the interaction of trypanocide guanyl hydrazones with B-DNA
OA Santos-Filho, JD Figueroa-Villar, MT Araujo
Bioorganic & Medicinal Chemistry Letters 7 (13), 1797-1802, 1997
251997
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