Osvaldo Andrade Santos-Filho
Osvaldo Andrade Santos-Filho
Professor of Physical Chemistry and Molecular Modeling, Federal University of Rio de Janeiro
Verified email at
Cited by
Cited by
Design, synthesis, and antiviral activity of new 1H-1, 2, 3-triazole nucleoside ribavirin analogs
M de Lourdes G Ferreira, L Pinheiro, OA Santos-Filho, MDS Peçanha, ...
Medicinal Chemistry Research 23 (3), 1501-1511, 2014
Dietary flavonoids fisetin, luteolin and their derived compounds inhibit arginase, a central enzyme in Leishmania (Leishmania) amazonensis infection
LC Manjolin, MBG dos Reis, C do Carmo Maquiaveli, OA Santos-Filho, ...
Food chemistry 141 (3), 2253-2262, 2013
Rational design of new antituberculosis agents: Receptor-independent four-dimensional quantitative structure− activity relationship analysis of a set of isoniazid derivatives
KFM Pasqualoto, EI Ferreira, OA Santos-Filho, AJ Hopfinger
Journal of medicinal chemistry 47 (15), 3755-3764, 2004
Modelagem de proteínas por homologia
OA Santos Filho, RB Alencastro
Química Nova 26, 253-259, 2003
Mapping the Protein Interaction Network in Methicillin-Resistant Staphylococcus aureus
A Cherkasov, M Hsing, R Zoraghi, LJ Foster, RH See, N Stoynov, J Jiang, ...
Journal of proteome research 10 (3), 1139-1150, 2011
Inhibition of Leishmania (Leishmania) amazonensis and Rat Arginases by Green Tea EGCG, (+)-Catechin and (−)-Epicatechin: A Comparative Structural Analysis …
MBG dos Reis, LC Manjolin, CC Maquiaveli, OA Santos-Filho, ...
PLoS One 8 (11), e78387, 2013
Molecular modeling of wild-type and antifolate resistant mutant Plasmodium falciparum DHFR
RT Delfino, OA Santos-Filho, JD Figueroa-Villar
Biophysical chemistry 98 (3), 287-300, 2002
New Trifluoromethyl Triazolopyrimidines as Anti-Plasmodiumfalciparum Agents
N Boechat, LCS Pinheiro, TS Silva, ACC Aguiar, AS Carvalho, MM Bastos, ...
Molecules 17 (7), 8285-8302, 2012
Design and Synthesis of New N-(5-Trifluoromethyl)-1H-1,2,4-triazol-3-yl Benzenesulfonamides as Possible Antimalarial Prototypes
N Boechat, LCS Pinheiro, OA Santos-Filho, IC Silva
Molecules 16 (9), 8083-8097, 2011
A search for sources of drug resistance by the 4D-QSAR analysis of a set of antimalarial dihydrofolate reductase inhibitors
OA Santos-Filho, AJ Hopfinger
Journal of computer-aided molecular design 15 (1), 1-12, 2001
Type 2 antifolates in the chemotherapy of falciparum malaria
RT Delfino, OA Santos-Filho, JD Figueroa-Villar
Journal of the Brazilian Chemical Society 13, 727-741, 2002
An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin
A Cherkasov, F Ban, O Santos-Filho, N Thorsteinson, M Fallahi, ...
Journal of medicinal chemistry 51 (7), 2047-2056, 2008
The receptor-dependent QSAR paradigm: an overview of the current state of the art
OA Santos-Filho, AJ Hopfinger, A Cherkasov, RB de Alencastro
Medicinal Chemistry 5 (4), 359-366, 2009
Free energy force field (FEFF) 3D-QSAR analysis of a set of Plasmodium falciparum dihydrofolate reductase inhibitors
OA Santos-Filho, RK Mishra, AJ Hopfinger
Journal of Computer-Aided Molecular Design 15 (9), 787-810, 2001
Homology modeling of wild type and pyrimethamine/cycloguanil-cross resistant mutant type Plasmodium falciparum dihydrofolate reductase. A model for antimalarial chemotherapy …
OA Santos-Filho, RB de Alencastro, JD Figueroa-Villar
Biophysical Chemistry 91 (3), 305-317, 2001
Structure-based QSAR analysis of a set of 4-hydroxy-5, 6-dihydropyrones as inhibitors of HIV-1 protease: an application of the receptor-dependent (RD) 4D-QSAR formalism
OA Santos-Filho, AJ Hopfinger
Journal of chemical information and modeling 46 (1), 345-354, 2006
The 4D‐QSAR Paradigm: Application to a Novel Set of Non‐peptidic HIV Protease Inhibitors
OA Santos‐Filho, AJ Hopfinger
Quantitative Structure‐Activity Relationships 21 (4), 369-381, 2002
In silico identification of anthropogenic chemicals as ligands of zebrafish sex hormone binding globulin
N Thorsteinson, F Ban, O Santos-Filho, SMH Tabaei, S Miguel-Queralt, ...
Toxicology and applied pharmacology 234 (1), 47-57, 2009
Aureonitol, a fungi-derived tetrahydrofuran, inhibits influenza replication by targeting its surface glycoprotein hemagglutinin
CQ Sacramento, A Marttorelli, N Fintelman-Rodrigues, CS de Freitas, ...
PLoS One 10 (10), e0139236, 2015
Molecular modeling of the interaction of trypanocide guanyl hydrazones with B-DNA
OA Santos-Filho, JD Figueroa-Villar, MT Araujo
Bioorganic & Medicinal Chemistry Letters 7 (13), 1797-1802, 1997
The system can't perform the operation now. Try again later.
Articles 1–20