David Geoffrey Spiller
David Geoffrey Spiller
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Oscillations in NF-κB signaling control the dynamics of gene expression
DE Nelson, AEC Ihekwaba, M Elliott, JR Johnson, CA Gibney, ...
Science 306 (5696), 704-708, 2004
Pulsatile stimulation determines timing and specificity of NF-κB-dependent transcription
L Ashall, CA Horton, DE Nelson, P Paszek, CV Harper, K Sillitoe, S Ryan, ...
Science 324 (5924), 242-246, 2009
Measurement of single-cell dynamics
DG Spiller, CD Wood, DA Rand, MRH White
Nature 465 (7299), 736-745, 2010
Encoded microcarriers for high‐throughput multiplexed detection
R Wilson, AR Cossins, DG Spiller
Angewandte Chemie International Edition 45 (37), 6104-6117, 2006
The mitochondrial network of human neutrophils: role in chemotaxis, phagocytosis, respiratory burst activation, and commitment to apoptosis
G Fossati, DA Moulding, DG Spiller, RJ Moots, MRH White, SW Edwards
The Journal of immunology 170 (4), 1964-1972, 2003
Inflammasome-dependent IL-1β release depends upon membrane permeabilisation
F Martín-Sánchez, C Diamond, M Zeitler, AI Gomez, A Baroja-Mazo, ...
Cell Death & Differentiation 23 (7), 1219-1231, 2016
Dynamic analysis of stochastic transcription cycles
CV Harper, B Finkenstädt, DJ Woodcock, S Friedrichsen, S Semprini, ...
PLoS biology 9 (4), e1000607, 2011
Population robustness arising from cellular heterogeneity
P Paszek, S Ryan, L Ashall, K Sillitoe, CV Harper, DG Spiller, DA Rand, ...
Proceedings of the National Academy of Sciences 107 (25), 11644-11649, 2010
Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia
DA Moulding, MP Blundell, DG Spiller, MRH White, GO Cory, Y Calle, ...
The Journal of experimental medicine 204 (9), 2213-2224, 2007
Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells
DA Moulding, RV Giles, DG Spiller, MRH White, DM Tidd, SW Edwards
Blood, The Journal of the American Society of Hematology 96 (5), 1756-1763, 2000
Edible mushroom (Agaricus bisporus) lectin, which reversibly inhibits epithelial cell proliferation, blocks nuclear localization sequence-dependent nuclear protein import
LG Yu, DG Fernig, MRH White, DG Spiller, P Appleton, RC Evans, ...
Journal of Biological Chemistry 274 (8), 4890-4899, 1999
Physiological levels of TNFα stimulation induce stochastic dynamics of NF-κB responses in single living cells
DA Turner, P Paszek, DJ Woodcock, DE Nelson, CA Horton, Y Wang, ...
Journal of cell science 123 (16), 2834-2843, 2010
Antisense Morpholino Oligonucleotide Analog Induces Missplicing of C-myc mRNA
RV Giles, DG Spiller, RE Clark, DM Tidd
Antisense and Nucleic Acid Drug Development 9 (2), 213-220, 1999
Expression of the leptin receptor in rat and human nodose ganglion neurones
G Burdyga, D Spiller, R Morris, S Lal, DG Thompson, S Saeed, ...
Neuroscience 109 (2), 339-347, 2002
Phosphoramidate oligonucleotides as potent antisense molecules in cells and in vivo
M Faria, DG Spiller, C Dubertret, JS Nelson, MRH White, D Scherman, ...
Nature biotechnology 19 (1), 40-44, 2001
Multi-parameter analysis of the kinetics of NF-κB signalling and transcription in single living cells
G Nelson, L Paraoan, DG Spiller, GJC Wilde, MA Browne, PK Djali, ...
Journal of cell science 115 (6), 1137-1148, 2002
Response to Comment on" Oscillations in NF-κB signaling control the dynamics of gene expression"
DE Nelson, CA Horton, V See, JR Johnson, G Nelson, DG Spiller, DB Kell, ...
Science 308 (5718), 52-52, 2005
Localization of orexin-1 receptors to vagal afferent neurons in the rat and humans
G Burdyga, S Lal, D Spiller, W Jiang, D Thompson, S Attwood, S Saeed, ...
Gastroenterology 124 (1), 129-139, 2003
Selecting optimal oligonucleotide composition for maximal antisense effect following streptolysin O-mediated delivery into human leukaemia cells
RV Giles, DG Spiller, J Grzybowski, RE Clark, P Nicklin, DM Tidd
Nucleic Acids Research 26 (7), 1567-1575, 1998
Improving the intracellular delivery and molecular efficacy of antisense oligonucleotides in chronic myeloid leukemia cells: a comparison of streptolysin-O permeabilization …
DG Spiller, RV Giles, J Grzybowski, DM Tidd, RE Clark
Blood, The Journal of the American Society of Hematology 91 (12), 4738-4746, 1998
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