| Oscillations in NF-κB signaling control the dynamics of gene expression DE Nelson, AEC Ihekwaba, M Elliott, JR Johnson, CA Gibney, ... Science 306 (5696), 704-708, 2004 | 1670 | 2004 |
| Pulsatile stimulation determines timing and specificity of NF-κB-dependent transcription L Ashall, CA Horton, DE Nelson, P Paszek, CV Harper, K Sillitoe, S Ryan, ... Science 324 (5924), 242-246, 2009 | 680 | 2009 |
| Measurement of single-cell dynamics DG Spiller, CD Wood, DA Rand, MRH White Nature 465 (7299), 736-745, 2010 | 475 | 2010 |
| Encoded microcarriers for high‐throughput multiplexed detection R Wilson, AR Cossins, DG Spiller Angewandte Chemie International Edition 45 (37), 6104-6117, 2006 | 464 | 2006 |
| The mitochondrial network of human neutrophils: role in chemotaxis, phagocytosis, respiratory burst activation, and commitment to apoptosis G Fossati, DA Moulding, DG Spiller, RJ Moots, MRH White, SW Edwards The Journal of immunology 170 (4), 1964-1972, 2003 | 417 | 2003 |
| Inflammasome-dependent IL-1β release depends upon membrane permeabilisation F Martín-Sánchez, C Diamond, M Zeitler, AI Gomez, A Baroja-Mazo, ... Cell Death & Differentiation 23 (7), 1219-1231, 2016 | 299 | 2016 |
| Dynamic analysis of stochastic transcription cycles CV Harper, B Finkenstädt, DJ Woodcock, S Friedrichsen, S Semprini, ... PLoS biology 9 (4), e1000607, 2011 | 261 | 2011 |
| Population robustness arising from cellular heterogeneity P Paszek, S Ryan, L Ashall, K Sillitoe, CV Harper, DG Spiller, DA Rand, ... Proceedings of the National Academy of Sciences 107 (25), 11644-11649, 2010 | 234 | 2010 |
| Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia DA Moulding, MP Blundell, DG Spiller, MRH White, GO Cory, Y Calle, ... The Journal of experimental medicine 204 (9), 2213-2224, 2007 | 197 | 2007 |
| Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells DA Moulding, RV Giles, DG Spiller, MRH White, DM Tidd, SW Edwards Blood, The Journal of the American Society of Hematology 96 (5), 1756-1763, 2000 | 179 | 2000 |
| Edible mushroom (Agaricus bisporus) lectin, which reversibly inhibits epithelial cell proliferation, blocks nuclear localization sequence-dependent nuclear protein import LG Yu, DG Fernig, MRH White, DG Spiller, P Appleton, RC Evans, ... Journal of Biological Chemistry 274 (8), 4890-4899, 1999 | 173 | 1999 |
| Physiological levels of TNFα stimulation induce stochastic dynamics of NF-κB responses in single living cells DA Turner, P Paszek, DJ Woodcock, DE Nelson, CA Horton, Y Wang, ... Journal of cell science 123 (16), 2834-2843, 2010 | 169 | 2010 |
| Antisense Morpholino Oligonucleotide Analog Induces Missplicing of C-myc mRNA RV Giles, DG Spiller, RE Clark, DM Tidd Antisense and Nucleic Acid Drug Development 9 (2), 213-220, 1999 | 156 | 1999 |
| Phosphoramidate oligonucleotides as potent antisense molecules in cells and in vivo M Faria, DG Spiller, C Dubertret, JS Nelson, MRH White, D Scherman, ... Nature biotechnology 19 (1), 40-44, 2001 | 151 | 2001 |
| Expression of the leptin receptor in rat and human nodose ganglion neurones G Burdyga, D Spiller, R Morris, S Lal, DG Thompson, S Saeed, ... Neuroscience 109 (2), 339-347, 2002 | 149 | 2002 |
| Multi-parameter analysis of the kinetics of NF-κB signalling and transcription in single living cells G Nelson, L Paraoan, DG Spiller, GJC Wilde, MA Browne, PK Djali, ... Journal of cell science 115 (6), 1137-1148, 2002 | 147 | 2002 |
| Response to Comment on" Oscillations in NF-κB signaling control the dynamics of gene expression" DE Nelson, CA Horton, V See, JR Johnson, G Nelson, DG Spiller, DB Kell, ... Science 308 (5718), 52-52, 2005 | 138 | 2005 |
| Localization of orexin-1 receptors to vagal afferent neurons in the rat and humans G Burdyga, S Lal, D Spiller, W Jiang, D Thompson, S Attwood, S Saeed, ... Gastroenterology 124 (1), 129-139, 2003 | 131 | 2003 |
| Selecting optimal oligonucleotide composition for maximal antisense effect following streptolysin O-mediated delivery into human leukaemia cells RV Giles, DG Spiller, J Grzybowski, RE Clark, P Nicklin, DM Tidd Nucleic Acids Research 26 (7), 1567-1575, 1998 | 125 | 1998 |
| Improving the intracellular delivery and molecular efficacy of antisense oligonucleotides in chronic myeloid leukemia cells: a comparison of streptolysin-O permeabilization … DG Spiller, RV Giles, J Grzybowski, DM Tidd, RE Clark Blood, The Journal of the American Society of Hematology 91 (12), 4738-4746, 1998 | 124 | 1998 |
