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Thomas C.R. Miller
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Year
Molecular architecture of polycomb repressive complexes
EC Chittock, S Latwiel, TCR Miller, CW Müller
Biochemical Society Transactions 45 (1), 193-205, 2017
2012017
A bromodomain–DNA interaction facilitates acetylation-dependent bivalent nucleosome recognition by the BET protein BRDT
TCR Miller, B Simon, V Rybin, H Grötsch, S Curtet, S Khochbin, ...
Nature communications 7 (1), 13855, 2016
1222016
Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM
TCR Miller, J Locke, JF Greiwe, JFX Diffley, A Costa
Nature 575 (7784), 704-710, 2019
1172019
Competitive binding of a benzimidazole to the histone-binding pocket of the Pygo PHD finger
TCR Miller, TJ Rutherford, K Birchall, J Chugh, M Fiedler, M Bienz
ACS chemical biology 9 (12), 2864-2874, 2014
662014
Allosteric remodelling of the histone H3 binding pocket in the Pygo2 PHD finger triggered by its binding to the B9L/BCL9 co-factor
TCR Miller, TJ Rutherford, CM Johnson, M Fiedler, M Bienz
Journal of molecular biology 401 (5), 969-984, 2010
532010
Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase
JF Greiwe, TCR Miller, J Locke, F Martino, S Howell, A Schreiber, A Nans, ...
Nature structural & molecular biology 29 (1), 10-20, 2022
272022
The architecture and function of the chromatin replication machinery
TCR Miller, A Costa
Current opinion in structural biology 47, 9-16, 2017
232017
Structural basis for the activation of the deubiquitinase Calypso by the Polycomb protein ASX
I De, EC Chittock, H Grötsch, TCR Miller, AA McCarthy, CW Müller
Structure 27 (3), 528-536. e4, 2019
212019
A synthetic biology approach to probing nucleosome symmetry
Y Ichikawa, CF Connelly, A Appleboim, TCR Miller, H Jacobi, NA Abshiru, ...
elife 6, e28836, 2017
212017
Evolutionary adaptation of the fly Pygo PHD finger toward recognizing histone H3 tail methylated at arginine 2
TCR Miller, J Mieszczanek, MJ Sánchez-Barrena, TJ Rutherford, ...
Structure 21 (12), 2208-2220, 2013
172013
Solving the MCM paradox by visualizing the scaffold of CMG helicase at active replisomes
H Polasek-Sedlackova, TCR Miller, J Krejci, MB Rask, J Lukas
Nature Communications 13 (1), 6090, 2022
42022
In silico reconstitution of DNA replication. Lessons from single-molecule imaging and cryo-tomography applied to single-particle cryo-EM
JF Greiwe, G Zanetti, TCR Miller, A Costa
Current Opinion in Structural Biology 72, 279-286, 2022
32022
ReconSil: An electron microscopy toolbox to study helicase function at an origin of replication
T Pühringer, JF Greiwe, TCR Miller, A Costa
Methods in Enzymology 672, 203-231, 2022
12022
MCM Double Hexamer Loading Visualised with Human Proteins
F Weissmann, JF Greiwe, T Pühringer, TCR Miller, JFX Diffley, A Costa
bioRxiv, 2024.04. 10.588848, 2024
2024
Cell Cycle Regulation has Shaped Budding Yeast Replication Origin Structure and Function
J Diffley, CT Lim, TCR Miller, KW Tan, saurabh Talele, A Early, P East, ...
bioRxiv, 2024.01. 10.575016, 2024
2024
Catalytic and non-catalytic functions of DNA polymerase kappa in translesion DNA synthesis
S Sellés-Baiget, SM Ambjørn, A Carli, IA Hendriks, I Gallina, NE Davey, ...
bioRxiv, 2023.11. 06.565773, 2023
2023
Histone decoding by the Pygo-BCL9 complex: a target for small molecule inhibition of Wnt signalling
TCR Miller
2012
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Articles 1–17