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Gregory Costain
Gregory Costain
Physician-Scientist, The Hospital for Sick Children & University of Toronto
Verified email at sickkids.ca - Homepage
Title
Cited by
Cited by
Year
Improved diagnostic yield compared with targeted gene sequencing panels suggests a role for whole-genome sequencing as a first-tier genetic test
AC Lionel, G Costain, N Monfared, S Walker, MS Reuter, SM Hosseini, ...
Genetics in Medicine 20 (4), 435-443, 2018
5112018
Practical guidelines for managing adults with 22q11. 2 deletion syndrome
WLA Fung, NJ Butcher, G Costain, DM Andrade, E Boot, EWC Chow, ...
Genetics in Medicine 17 (8), 599-609, 2015
2952015
Reappraisal of reported genes for sudden arrhythmic death: evidence-based evaluation of gene validity for Brugada syndrome
SM Hosseini, R Kim, S Udupa, G Costain, R Jobling, E Liston, SM Jamal, ...
Circulation 138 (12), 1195-1205, 2018
2912018
Rare copy number variations in adults with tetralogy of Fallot implicate novel risk gene pathways
CK Silversides, AC Lionel, G Costain, D Merico, O Migita, B Liu, T Yuen, ...
Public Library of Science 8 (8), e1002843, 2012
1962012
Rare exonic deletions implicate the synaptic organizer Gephyrin (GPHN) in risk for autism, schizophrenia and seizures
AC Lionel, AK Vaags, D Sato, MJ Gazzellone, EB Mitchell, HY Chen, ...
Human molecular genetics 22 (10), 2055-2066, 2013
1832013
Pathogenic rare copy number variants in community-based schizophrenia suggest a potential role for clinical microarrays
G Costain, AC Lionel, D Merico, P Forsythe, K Russell, C Lowther, T Yuen, ...
Human molecular genetics 22 (22), 4485-4501, 2013
1382013
Delineating the 15q13. 3 microdeletion phenotype: a case series and comprehensive review of the literature
C Lowther, G Costain, DJ Stavropoulos, R Melvin, CK Silversides, ...
Genetics in Medicine 17 (2), 149-157, 2015
1352015
A large data resource of genomic copy number variation across neurodevelopmental disorders
M Zarrei, CL Burton, W Engchuan, EJ Young, EJ Higginbotham, ...
NPJ genomic medicine 4 (1), 26, 2019
1322019
Periodic reanalysis of whole-genome sequencing data enhances the diagnostic advantage over standard clinical genetic testing
G Costain, R Jobling, S Walker, MS Reuter, M Snell, S Bowdin, RD Cohn, ...
European Journal of Human Genetics 26 (5), 740-744, 2018
1222018
Genetic contributors to risk of schizophrenia in the presence of a 22q11. 2 deletion
I Cleynen, W Engchuan, MS Hestand, T Heung, AM Holleman, ...
Molecular psychiatry 26 (8), 4496-4510, 2021
1072021
Rare genome-wide copy number variation and expression of schizophrenia in 22q11. 2 deletion syndrome
AS Bassett, C Lowther, D Merico, G Costain, EWC Chow, ...
American Journal of Psychiatry 174 (11), 1054-1063, 2017
942017
Clinical application of targeted next-generation sequencing panels and whole exome sequencing in childhood epilepsy
G Costain, D Cordeiro, D Matviychuk, S Mercimek-Andrews
Neuroscience 418, 291-310, 2019
882019
Functional outcomes of adults with 22q11. 2 deletion syndrome
NJ Butcher, EWC Chow, G Costain, D Karas, A Ho, AS Bassett
Genetics in medicine 14 (10), 836-843, 2012
862012
Clinically detectable copy number variations in a Canadian catchment population of schizophrenia
AS Bassett, G Costain, WLA Fung, KJ Russell, L Pierce, R Kapadia, ...
Journal of psychiatric research 44 (15), 1005-1009, 2010
842010
Genomic architecture of autism from comprehensive whole-genome sequence annotation
B Trost, B Thiruvahindrapuram, AJS Chan, W Engchuan, ...
Cell 185 (23), 4409-4427. e18, 2022
752022
The importance of copy number variation in congenital heart disease
G Costain, CK Silversides, AS Bassett
NPJ genomic medicine 1 (1), 1-11, 2016
742016
Copy number variable microRNAs in schizophrenia and their neurodevelopmental gene targets
W Warnica, D Merico, G Costain, SE Alfred, J Wei, CR Marshall, ...
Biological psychiatry 77 (2), 158-166, 2015
732015
Clinical applications of schizophrenia genetics: genetic diagnosis, risk, and counseling in the molecular era
G Costain, AS Bassett
The application of clinical genetics, 1-18, 2012
722012
Parental origin of interstitial duplications at 15q11. 2-q13. 3 in schizophrenia and neurodevelopmental disorders
AR Isles, A Ingason, C Lowther, J Walters, M Gawlick, G Stöber, E Rees, ...
PLoS genetics 12 (5), e1005993, 2016
712016
Haploinsufficiency of vascular endothelial growth factor related signaling genes is associated with tetralogy of Fallot
MS Reuter, R Jobling, RR Chaturvedi, R Manshaei, G Costain, T Heung, ...
Genetics in Medicine 21 (4), 1001-1007, 2019
682019
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