| The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9–dependent innate immune responses in the liver AT Martino, M Suzuki, DM Markusic, I Zolotukhin, RC Ryals, B Moghimi, ... Blood, The Journal of the American Society of Hematology 117 (24), 6459-6468, 2011 | 235 | 2011 |
| Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells AT Martino, E Basner-Tschakarjan, DM Markusic, JD Finn, C Hinderer, ... Blood, The Journal of the American Society of Hematology 121 (12), 2224-2233, 2013 | 175 | 2013 |
| Innate immune responses to AAV vectors GL Rogers, AT Martino, GV Aslanidi, GR Jayandharan, A Srivastava, ... Frontiers in microbiology 2, 194, 2011 | 175 | 2011 |
| Nonredundant roles of IL-10 and TGF-β in suppression of immune responses to hepatic AAV-factor IX gene transfer BE Hoffman, AT Martino, BK Sack, O Cao, G Liao, C Terhorst, RW Herzog Molecular therapy 19 (7), 1263-1272, 2011 | 120 | 2011 |
| Activation of the NF-κB pathway by adeno-associated virus (AAV) vectors and its implications in immune response and gene therapy GR Jayandharan, G Aslanidi, AT Martino, SC Jahn, GQ Perrin, ... Proceedings of the National Academy of Sciences 108 (9), 3743-3748, 2011 | 103 | 2011 |
| Interleukin 10 (IL-10) regulatory cytokine and its clinical consequences E Bijjiga, AT Martino J Clin Cell Immunol S 1 (2), 10.4172, 2013 | 75 | 2013 |
| Immune response mechanisms against AAV vectors in animal models AT Martino, DM Markusic Molecular Therapy-Methods & Clinical Development 17, 198-208, 2020 | 71 | 2020 |
| Tolerance induction to cytoplasmic β-galactosidase by hepatic AAV gene transfer—implications for antigen presentation and immunotoxicity AT Martino, S Nayak, BE Hoffman, M Cooper, G Liao, DM Markusic, ... PloS one 4 (8), e6376, 2009 | 69 | 2009 |
| Recombinant AAV serotype and capsid mutant comparison for pulmonary gene transfer of α-1-antitrypsin using invasive and noninvasive delivery RL Wang, T McLaughlin, T Cossette, Q Tang, K Foust, ... Molecular Therapy 17 (1), 81-87, 2009 | 57 | 2009 |
| Role of the vector genome and underlying factor IX mutation in immune responses to AAV gene therapy for hemophilia B GL Rogers, AT Martino, I Zolotukhin, HCJ Ertl, RW Herzog Journal of translational medicine 12, 1-10, 2014 | 48 | 2014 |
| Pre-clinical assessment of immune responses to adeno-associated virus (AAV) vectors E Basner-Tschakarjan, E Bijjiga, AT Martino Frontiers in immunology 5, 71136, 2014 | 45 | 2014 |
| Partial correction of the CFTR‐dependent ABPA mouse model with recombinant adeno‐associated virus gene transfer of truncated CFTR gene C Mueller, D Torrez, S Braag, A Martino, T Clarke, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2008 | 42 | 2008 |
| Measuring immune responses to recombinant AAV gene transfer AT Martino, RW Herzog, I Anegon, O Adjali Adeno-Associated Virus: Methods and Protocols, 259-272, 2011 | 40 | 2011 |
| Regulatory T cells and TLR9 activation shape antibody formation to a secreted transgene product in AAV muscle gene transfer RW Herzog, M Cooper, GQ Perrin, M Biswas, AT Martino, L Morel, ... Cellular immunology 342, 103682, 2019 | 37 | 2019 |
| The α7 nicotinic acetylcholine receptor agonist, GTS-21, attenuates hyperoxia-induced acute inflammatory lung injury by alleviating the accumulation of HMGB1 in the airways and … RA Sitapara, AG Gauthier, SI Valdés-Ferrer, M Lin, V Patel, M Wang, ... Molecular Medicine 26, 1-12, 2020 | 35 | 2020 |
| 101. Toxicology and Biodistribution Studies of a Recombinant Adeno-Associated Virus 2 (rAAV2) Alpha-1 Antitrypsin (AAT) Vector AE Poirier, LA Combee, AT Martino, TR Flotte Molecular Therapy 9 (S1), S40, 2004 | 26 | 2004 |
| The pros and cons of immunomodulatory IL-10 gene therapy with recombinant AAV in a Cftr−/−-dependent allergy mouse model C Mueller, SA Braag, AT Martino, Q Tang, M Campbell-Thompson, ... Gene therapy 16 (2), 172-183, 2009 | 23 | 2009 |
| N-Glycosylation Augmentation of the Cystic Fibrosis Epithelium Improves Pseudomonas aeruginosa Clearance AT Martino, C Mueller, S Braag, PE Cruz, M Campbell-Thompson, S Jin, ... American Journal of Respiratory Cell and Molecular Biology 44 (6), 824-830, 2011 | 10 | 2011 |
| Insulin therapy improves adeno-associated virus transduction of liver and skeletal muscle in mice and cultured cells S Carrig, E Bijjiga, MJ Wopat, AT Martino Human Gene Therapy 27 (11), 892-905, 2016 | 5 | 2016 |
| Immunology of gene and cell therapy DM Markusic, AT Martino, CD Porada, T VandenDriessche Molecular Therapy 28 (3), 691-692, 2020 | 3 | 2020 |
