Sigma receptors: biology and function. JM Walker, WD Bowen, FO Walker, RR Matsumoto, B De Costa, KC Rice Pharmacological reviews 42 (4), 355-402, 1990 | 1122 | 1990 |
A proposal for the classification of sigma binding sites R Quirion Trends Pharmacol Sci 13, 85-86, 1992 | 957 | 1992 |
Sigma-1 and sigma-2 receptors are expressed in a wide variety of human and rodent tumor cell lines BJ Vilner, CS John, WD Bowen Cancer research 55 (2), 408-413, 1995 | 654 | 1995 |
Rat liver and kidney contain high densities of σ1 and σ2 receptors: characterization by ligand binding and photoaffinity labeling SB Hellewell, A Bruce, G Feinstein, J Orringer, W Williams, WD Bowen European Journal of Pharmacology: Molecular Pharmacology 268 (1), 9-18, 1994 | 548 | 1994 |
A sigma-like binding site in rat pheochromocytoma (PC12) cells: decreased affinity for (+)-benzomorphans and lower molecular weight suggest a different sigma receptor form from … SB Hellewell, WD Bowen Brain research 527 (2), 244-253, 1990 | 520 | 1990 |
Differential antagonism of opioid delta antinociception by [D-Ala2, Leu5, Cys6] enkephalin and naltrindole 5'-isothiocyanate: evidence for delta receptor subtypes. Q Jiang, AE Takemori, M Sultana, PS Portoghese, WD Bowen, ... Journal of Pharmacology and Experimental Therapeutics 257 (3), 1069-1075, 1991 | 376 | 1991 |
Sigma-2 receptor agonists activate a novel apoptotic pathway and potentiate antineoplastic drugs in breast tumor cell lines KW Crawford, WD Bowen Cancer research 62 (1), 313-322, 2002 | 339 | 2002 |
Sigma receptors: recent advances and new clinical potentials WD Bowen Pharmaceutica Acta Helvetiae 74 (2-3), 211-218, 2000 | 335 | 2000 |
Characterization of two novel σ receptor ligands: antidystonic effects in rats suggest σ receptor antagonism RR Matsumoto, WD Bowen, MA Tom, DD Truong, BR De Costa European journal of pharmacology 280 (3), 301-310, 1995 | 299 | 1995 |
Interconverting mu and delta forms of the opiate receptor in rat striatal patches. WD Bowen, S Gentleman, M Herkenham, CB Pert Proceedings of the National Academy of Sciences 78 (8), 4818-4822, 1981 | 244 | 1981 |
Modulation of cellular calcium by sigma-2 receptors: release from intracellular stores in human SK-N-SH neuroblastoma cells BJ Vilner, WD Bowen Journal of Pharmacology and Experimental Therapeutics 292 (3), 900-911, 2000 | 241 | 2000 |
Cytotoxic effects of sigma ligands: sigma receptor-mediated alterations in cellular morphology and viability BJ Vilner, BR de Costa, WD Bowen Journal of Neuroscience 15 (1), 117-134, 1995 | 219 | 1995 |
Evidence for a role of haloperidol‐sensitive σ‐'opiate'receptors in the motor effects of antipsychotic drugs JM Walker, RR Matsumoto, WD Bowen, DL Gans, KD Jones, FO Walker Neurology 38 (6), 961-961, 1988 | 215 | 1988 |
Evidence for a multi-site model of the rat brain σ receptor WD Bowen, SB Hellewell, KA McGarry European journal of pharmacology 163 (2-3), 309-318, 1989 | 187 | 1989 |
Synthesis and evaluation of optically pure [3H]‐(+)‐pentazocine, a highly potent and selective radioligand for σ receptors BR de Costa, WD Bowen, SB Hellewell, JM Walker, A Thurkauf, ... FEBS letters 251 (1-2), 53-58, 1989 | 162 | 1989 |
Pentazocine: a potent and highly selective benzomorphan-based probe for sigma-1 receptors WD Bowen, BR De Costa, SB Hellewell, JM Walker, KC Rice Mol Neuropharmacol 3 (2), 117-126, 1993 | 161 | 1993 |
Metabolites of haloperidol display preferential activity at σ receptors compared to dopamine D-2 receptors WD Bowen, EL Moses, PJ Tolentino, JM Walker European journal of pharmacology 177 (3), 111-118, 1990 | 153 | 1990 |
Role of sigma-1 receptor C-terminal segment in inositol 1, 4, 5-trisphosphate receptor activation: constitutive enhancement of calcium signaling in MCF-7 tumor cells Z Wu, WD Bowen Journal of biological chemistry 283 (42), 28198-28215, 2008 | 152 | 2008 |
Modulation of mu-mediated antinociception in the mouse involves opioid delta-2 receptors. F Porreca, AE Takemori, M Sultana, PS Portoghese, WD Bowen, ... Journal of Pharmacology and Experimental Therapeutics 263 (1), 147-152, 1992 | 151 | 1992 |
Sigma receptors negatively modulate agonist-stimulated phosphoinositide metabolism in rat brain W Bowen, B Kirschner, S Hellewell, A Newman, K Rice Problems of Drug Dependence 1988, 354, 1988 | 149 | 1988 |