| Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor DW Fry, AJ Bridges, WA Denny, A Doherty, KD Greis, JL Hicks, KE Hook, ... Proceedings of the National Academy of Sciences 95 (20), 12022-12027, 1998 | 549 | 1998 |
| Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality DA Chan, PD Sutphin, P Nguyen, S Turcotte, EW Lai, A Banh, ... Science translational medicine 3 (94), 94ra70-94ra70, 2011 | 512 | 2011 |
| Tyrosine kinase inhibitors. 8. An unusually steep structure− activity relationship for analogues of 4-(3-bromoanilino)-6, 7-dimethoxyquinazoline (PD 153035), a potent inhibitor … AJ Bridges, H Zhou, DR Cody, GW Rewcastle, A McMichael, ... Journal of medicinal chemistry 39 (1), 267-276, 1996 | 427 | 1996 |
| Prodrug strategies in cancer therapy WA Denny European journal of medicinal chemistry 36 (7-8), 577-595, 2001 | 421 | 2001 |
| Potential antitumor agents. 59. Structure-activity relationships for 2-phenylbenzimidazole-4-carboxamides, a new class of minimal DNA-intercalating agents which may not act via … WA Denny, GW Rewcastle, BC Baguley Journal of medicinal chemistry 33 (2), 814-819, 1990 | 414 | 1990 |
| Interactions of antitumor drugs with natural DNA: proton NMR study of binding mode and kinetics J Feigon, WA Denny, W Leupin, DR Kearns Journal of medicinal chemistry 27 (4), 450-465, 1984 | 381 | 1984 |
| Acridine derivatives as chemotherapeutic agents WA Denny Current Medicinal Chemistry 9 (18), 1655-1665, 2002 | 363 | 2002 |
| Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino) quinazoline-and 4-(phenylamino) pyrido [3, 2-d] pyrimidine-6 … JB Smaill, GW Rewcastle, JA Loo, KD Greis, OH Chan, EL Reyner, ... Journal of medicinal chemistry 43 (7), 1380-1397, 2000 | 361 | 2000 |
| DNA-intercalating ligands as anti-cancer drugs: prospects for future design. WA Denny Anti-cancer drug design 4 (4), 241-263, 1989 | 336 | 1989 |
| Tyrosine kinase inhibitors. 5. Synthesis and structure-activity relationships for 4-[(phenylmethyl) amino]-and 4-(phenylamino) quinazolines as potent adenosine 5'-triphosphate … GW Rewcastle, WA Denny, AJ Bridges, H Zhou, DR Cody, A McMichael, ... Journal of medicinal chemistry 38 (18), 3482-3487, 1995 | 332 | 1995 |
| Two-dimensional proton nuclear magnetic resonance investigation of the synthetic deoxyribonucleic acid decamer d (ATATCGATAT) J Feigon, W Leupin, WA Denny, DR Kearns Biochemistry 22 (25), 5943-5951, 1983 | 289 | 1983 |
| Potential antitumor agents. 34. Quantitative relationships between DNA binding and molecular structure for 9-anilinoacridines substituted in the anilino ring BC Baguley, WA Denny, GJ Atwell, BF Cain Journal of medicinal chemistry 24 (2), 170-177, 1981 | 283 | 1981 |
| Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family AJ Bridges, WA Denny, D Fry, A Kraker, RF Meyer, GW Rewcastle, ... US Patent 5,654,307, 1997 | 276 | 1997 |
| A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy S Turcotte, DA Chan, PD Sutphin, MP Hay, WA Denny, AJ Giaccia Cancer cell 14 (1), 90-102, 2008 | 273 | 2008 |
| A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation J Datta, K Ghoshal, WA Denny, SA Gamage, DG Brooke, P Phiasivongsa, ... Cancer research 69 (10), 4277-4285, 2009 | 272 | 2009 |
| Potential antitumor agents. 50. In vivo solid-tumor activity of derivatives of N-[2-(dimethylamino) ethyl] acridine-4-carboxamide GJ Atwell, GW Rewcastle, BC Baguley, WA Denny Journal of medicinal chemistry 30 (4), 664-669, 1987 | 268 | 1987 |
| Genotoxicity of non-covalent interactions: DNA intercalators LR Ferguson, WA Denny Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 623 (1 …, 2007 | 265 | 2007 |
| Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling C Chaussade, GW Rewcastle, JD Kendall, WA Denny, K Cho, ... Biochemical Journal 404 (3), 449-458, 2007 | 250 | 2007 |
| Potential antitumor agents. 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9H-xanthene-4-acetic acids GW Rewcastle, GJ Atwell, L Zhuang, BC Baguley, WA Denny Journal of medicinal chemistry 34 (1), 217-222, 1991 | 246 | 1991 |
| Mechanism of action and preclinical antitumor activity of the novel hypoxia-activated DNA cross-linking agent PR-104 AV Patterson, DM Ferry, SJ Edmunds, Y Gu, RS Singleton, K Patel, ... Clinical Cancer Research 13 (13), 3922-3932, 2007 | 244 | 2007 |
William WilsonVerified email at schk12.us
