| Classification and mutation prediction from non–small cell lung cancer histopathology images using deep learning N Coudray, PS Ocampo, T Sakellaropoulos, N Narula, M Snuderl, ... Nature medicine 24 (10), 1559-1567, 2018 | 2271 | 2018 |
| Targeting mitochondrial structure sensitizes acute myeloid leukemia to venetoclax treatment X Chen, C Glytsou, H Zhou, S Narang, DE Reyna, A Lopez, ... Cancer discovery 9 (7), 890-909, 2019 | 207 | 2019 |
| A deep learning framework for predicting response to therapy in cancer T Sakellaropoulos, K Vougas, S Narang, F Koinis, A Kotsinas, A Polyzos, ... Cell reports 29 (11), 3367-3373. e4, 2019 | 169 | 2019 |
| Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries Y Gong, C Lazaris, T Sakellaropoulos, A Lozano, P Kambadur, ... Nature communications 9 (1), 542, 2018 | 141 | 2018 |
| An intrinsic role of IL-33 in Treg cell–mediated tumor immunoevasion A Hatzioannou, A Banos, T Sakelaropoulos, C Fedonidis, MS Vidali, ... Nature immunology 21 (1), 75-85, 2020 | 103 | 2020 |
| Machine learning and data mining frameworks for predicting drug response in cancer: An overview and a novel in silico screening process based on association rule mining K Vougas, T Sakellaropoulos, A Kotsinas, GRP Foukas, A Ntargaras, ... Pharmacology & therapeutics 203, 107395, 2019 | 102 | 2019 |
| Network-based technologies for early drug discovery C Fotis, A Antoranz, D Hatziavramidis, T Sakellaropoulos, ... Drug discovery today 23 (3), 626-635, 2018 | 82 | 2018 |
| NSD2 overexpression drives clustered chromatin and transcriptional changes in a subset of insulated domains P Lhoumaud, S Badri, J Rodriguez-Hernaez, T Sakellaropoulos, G Sethia, ... Nature communications 10 (1), 4843, 2019 | 70 | 2019 |
| H3K27ac bookmarking promotes rapid post-mitotic activation of the pluripotent stem cell program without impacting 3D chromatin reorganization B Pelham-Webb, A Polyzos, L Wojenski, A Kloetgen, J Li, ... Molecular cell 81 (8), 1732-1748. e8, 2021 | 63 | 2021 |
| The species translation challenge—a systems biology perspective on human and rat bronchial epithelial cells C Poussin, C Mathis, LG Alexopoulos, DE Messinis, RHJ Dulize, ... Scientific Data 1 (1), 1-14, 2014 | 51 | 2014 |
| Identification of drug-specific pathways based on gene expression data: application to drug induced lung injury IN Melas, T Sakellaropoulos, F Iorio, LG Alexopoulos, WY Loh, ... Integrative biology 7 (8), 904-920, 2015 | 49 | 2015 |
| MAPK pathway and B cells overactivation in multiple sclerosis revealed by phosphoproteomics and genomic analysis E Kotelnikova, NA Kiani, D Messinis, I Pertsovskaya, V Pliaka, ... Proceedings of the National Academy of Sciences 116 (19), 9671-9676, 2019 | 41 | 2019 |
| A deep learning approach for rapid mutational screening in melanoma RH Kim, S Nomikou, N Coudray, G Jour, Z Dawood, R Hong, E Esteva, ... BioRxiv, 610311, 2019 | 41 | 2019 |
| EpiMethylTag: simultaneous detection of ATAC-seq or ChIP-seq signals with DNA methylation P Lhoumaud, G Sethia, F Izzo, T Sakellaropoulos, V Snetkova, S Vidal, ... Genome biology 20, 1-12, 2019 | 31 | 2019 |
| Mechanism-based biomarker discovery A Antoranz, T Sakellaropoulos, J Saez-Rodriguez, LG Alexopoulos Drug discovery today 22 (8), 1209-1215, 2017 | 29 | 2017 |
| Cell-type-specific prediction of 3D chromatin organization enables high-throughput in silico genetic screening J Tan, N Shenker-Tauris, J Rodriguez-Hernaez, E Wang, ... Nature biotechnology 41 (8), 1140-1150, 2023 | 28 | 2023 |
| Deep learning and pathomics analyses reveal cell nuclei as important features for mutation prediction of BRAF-mutated melanomas RH Kim, S Nomikou, N Coudray, G Jour, Z Dawood, R Hong, E Esteva, ... Journal of Investigative Dermatology 142 (6), 1650-1658. e6, 2022 | 24 | 2022 |
| A crowd-sourcing approach for the construction of species-specific cell signaling networks E Bilal, T Sakellaropoulos, C Participants, IN Melas, DE Messinis, ... Bioinformatics 31 (4), 484-491, 2014 | 13 | 2014 |
| Phosphoprotein patterns predict trametinib responsiveness and optimal trametinib sensitisation strategies in melanoma J Rožanc, T Sakellaropoulos, A Antoranz, C Guttà, B Podder, V Vetma, ... Cell Death & Differentiation 26 (8), 1365-1378, 2019 | 12 | 2019 |
| Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis M Bernardo-Faura, M Rinas, J Wirbel, I Pertsovskaya, V Pliaka, ... Genome Medicine 13, 1-16, 2021 | 11 | 2021 |
