Follow
Bruce Verchere
Bruce Verchere
Professor of Medicine University of British Columbia and BC Children's Hospital Research Institute
Verified email at mail.ubc.ca - Homepage
Title
Cited by
Cited by
Year
Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes.
SE Kahn, S Andrikopoulos, CB Verchere
Diabetes 48 (2), 241-253, 1999
6361999
β-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment
LR Brunham, JK Kruit, TD Pape, JM Timmins, AQ Reuwer, Z Vasanji, ...
Nature medicine 13 (3), 340-347, 2007
4692007
Gut microbiota as a trigger for metabolic inflammation in obesity and type 2 diabetes
TPM Scheithauer, E Rampanelli, M Nieuwdorp, BA Vallance, ...
Frontiers in immunology 11, 571731, 2020
3692020
Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide.
CB Verchere, DA D'Alessio, RD Palmiter, GC Weir, S Bonner-Weir, ...
Proceedings of the National Academy of Sciences 93 (8), 3492-3496, 1996
3471996
The flavanol (−)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP …
F Meng, A Abedini, A Plesner, CB Verchere, DP Raleigh
Biochemistry 49 (37), 8127-8133, 2010
3052010
Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood
JD Trudeau, C Kelly-Smith, CB Verchere, JF Elliott, JP Dutz, DT Finegood, ...
The Journal of clinical investigation 111 (2), 217-223, 2003
2972003
Islet amyloid polypeptide and type 2 diabetes
L Marzban, K Park, CB Verchere
Experimental gerontology 38 (4), 347-351, 2003
2462003
Resident macrophages mediate islet amyloid polypeptide–induced islet IL-1β production and β-cell dysfunction
CY Westwell-Roper, JA Ehses, CB Verchere
Diabetes 63 (5), 1698-1711, 2014
2442014
Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence?
S Zraika, RL Hull, CB Verchere, A Clark, KJ Potter, PE Fraser, DP Raleigh, ...
Diabetologia 53, 1046-1056, 2010
2292010
IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction
C Westwell-Roper, DL Dai, G Soukhatcheva, KJ Potter, N van Rooijen, ...
The journal of immunology 187 (5), 2755-2765, 2011
2142011
Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts
KJ Potter, A Abedini, P Marek, AM Klimek, S Butterworth, M Driscoll, ...
Proceedings of the National Academy of Sciences 107 (9), 4305-4310, 2010
2012010
Different effects of FK506, rapamycin, and mycophenolate mofetil on glucose-stimulated insulin release and apoptosis in human islets
JD Johnson, Z Ao, P Ao, H Li, LJ Dai, Z He, M Tee, KJ Potter, AM Klimek, ...
Cell transplantation 18 (8), 833-845, 2009
1952009
A multi-year analysis of islet transplantation compared with intensive medical therapy on progression of complications in type 1 diabetes
GL Warnock, DM Thompson, RM Meloche, RJ Shapiro, Z Ao, P Keown, ...
Transplantation 86 (12), 1762-1766, 2008
1932008
Cholesterol in islet dysfunction and type 2 diabetes
LR Brunham, JK Kruit, CB Verchere, MR Hayden
The Journal of clinical investigation 118 (2), 403-408, 2008
1832008
HDL and LDL cholesterol significantly influence β-cell function in type 2 diabetes mellitus
JK Kruit, LR Brunham, CB Verchere, MR Hayden
Current opinion in lipidology 21 (3), 178-185, 2010
1772010
IL-33 reverses an obesity-induced deficit in visceral adipose tissue ST2+ T regulatory cells and ameliorates adipose tissue inflammation and insulin resistance
JM Han, D Wu, HC Denroche, Y Yao, CB Verchere, MK Levings
The Journal of Immunology 194 (10), 4777-4783, 2015
1762015
miR-33a modulates ABCA1 expression, cholesterol accumulation, and insulin secretion in pancreatic islets
N Wijesekara, L Zhang, MH Kang, T Abraham, A Bhattacharjee, ...
Diabetes 61 (3), 653-658, 2012
1662012
Moderate exercise attenuates caspase-3 activity, oxidative stress, and inhibits progression of diabetic renal disease in db/db mice
S Ghosh, M Khazaei, F Moien-Afshari, LS Ang, DJ Granville, CB Verchere, ...
American Journal of Physiology-Renal Physiology 296 (4), F700-F708, 2009
1622009
Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics
A Abedini, A Plesner, P Cao, Z Ridgway, J Zhang, LH Tu, CT Middleton, ...
Elife 5, e12977, 2016
1592016
Role of β-cell prohormone convertase (PC) 1/3 in processing of pro-islet amyloid polypeptide
L Marzban, G Trigo-Gonzalez, X Zhu, CJ Rhodes, PA Halban, DF Steiner, ...
Diabetes 53 (1), 141-148, 2004
1502004
The system can't perform the operation now. Try again later.
Articles 1–20