Ludmil B. Alexandrov

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David C WedgeProfessor of Cancer Genomics and Data Science, University of ManchesterVerified email at manchester.ac.uk
Inigo MartincorenaWellcome Sanger InstituteVerified email at sanger.ac.uk
Dmitry GordeninPI, Mechanisms of Genome Dynamics Group, NIEHSVerified email at niehs.nih.gov
Boian S. AlexandrovTheoretical Division, Los Alamos National LabVerified email at lanl.gov
David A. WheelerBaylor College of MedicineVerified email at bcm.edu
Christopher D SteeleVerified email at ucl.ac.uk
Nischalan PillayUCL Cancer InstituteVerified email at ucl.ac.uk
Kim O. RasmussenTheoretical Division, Los Alamos National LaboratoryVerified email at lanl.gov
Anny UshevaProfessor (associate) of SurgeryVerified email at brown.edu
John R McPhersonAssociate in Research, Centre for Computational Biology, Duke-NUS Graduate Medical SchoolVerified email at duke-nus.edu.sg
Arnoud BootCergentisVerified email at cergentis.com
Nicholas J HaradhvalaThe Broad InstituteVerified email at broadinstitute.org
Ville MustonenUniversity of HelsinkiVerified email at helsinki.fi
Kyle CovingtonCastle Biosciences Inc, Friendswood TXVerified email at castlebiosciences.com
Jose M. C. TubioMolecular Medicine and Chronic diseases Centre (CIMUS), University of Santiago de CompostelaVerified email at usc.es
Steven G. RozenDuke University School of MedicineVerified email at duke.edu
Jayendra ShindeCrosscope Inc.Verified email at crosscope.com
Anthony FullamEMBLVerified email at embl.de
Jessica Zucman-RossiUniversité Paris Cité, AP-HPVerified email at inserm.fr
Eric LetouzéSenior Researcher, INSERM U1162Verified email at inserm.fr

Ludmil B. Alexandrov

Professor, University of California San Diego

Verified email at ucsd.edu - Homepage

Computational Biology Cancer Genomics Mutagenesis Ageing Bioinformatics


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Signatures of mutational processes in human cancer LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ... Nature 500 (7463), 415-421, 2013	10457	2013
The repertoire of mutational signatures in human cancer LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AW Tian Ng, Y Wu, ... Nature 578 (7793), 94-101, 2020	2940	2020
Landscape of somatic mutations in 560 breast cancer whole-genome sequences S Nik-Zainal, H Davies, J Staaf, M Ramakrishna, D Glodzik, X Zou, ... Nature 534 (7605), 47-54, 2016	2320	2016
Mutational Processes Molding the Genomes of 21 Breast Cancers S Nik-Zainal, LB Alexandrov, DC Wedge, P Van Loo, CD Greenman, ... Cell 149 (5), 979-993, 2012	2149	2012
High burden and pervasive positive selection of somatic mutations in normal human skin I Martincorena, A Roshan, M Gerstung, P Ellis, P Van Loo, S McLaren, ... Science 348 (6237), 880-886, 2015	1842	2015
Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets K Schulze, S Imbeaud, E Letouzé, LB Alexandrov, J Calderaro, ... Nature Genetics 47 (5), 505–511, 2015	1743	2015
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020	1693	2020
The Life History of 21 Breast Cancers S Nik-Zainal, P Van Loo, DC Wedge, LB Alexandrov, CD Greenman, ... Cell 149 (5), 994-1007, 2012	1615	2012
The evolutionary history of lethal metastatic prostate cancer G Gundem, P Van Loo, B Kremeyer, LB Alexandrov, JMC Tubio, ... Nature 520 (7547), 353–357, 2015	1517	2015
Whole-genome landscapes of major melanoma subtypes NK Hayward, JS Wilmott, N Waddell, PA Johansson, MA Field, K Nones, ... Nature 545, 175–180, 2017	1389	2017
Deciphering Signatures of Mutational Processes Operative in Human Cancer LB Alexandrov, S Nik-Zainal, DC Wedge, PJ Campbell, MR Stratton Cell Reports 3 (1), 246-259, 2013	1336	2013
Mutational signatures associated with tobacco smoking in human cancer LB Alexandrov, YS Ju, K Haase, P Van Loo, I Martincorena, S Nik-Zainal, ... Science 354 (6312), 618-622, 2016	1117	2016
Clock-like mutational processes in human somatic cells LB Alexandrov, PH Jones, DC Wedge, JE Sale, PJ Campbell, ... Nature Genetics 47 (12), 1402–1407, 2015	1062	2015
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma N Bolli, H Avet-Loiseau, DC Wedge, P Van Loo, LB Alexandrov, ... Nature Communications 5 (2997), 2014	1014	2014
Timing, rates and spectra of human germline mutation R Rahbari, A Wuster, SJ Lindsay, RJ Hardwick, LB Alexandrov, S Al Turki, ... Nature Genetics 48, 126–133, 2016	957	2016
Subclonal diversification of primary breast cancer revealed by multiregion sequencing LR Yates, M Gerstung, S Knappskog, C Desmedt, G Gundem, P Van Loo, ... Nature Medicine 21 (7), 751-759, 2015	863	2015
Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours X Ma, YU Liu, Y Liu, LB Alexandrov, MN Edmonson, C Gawad, X Zhou, ... Nature 555 (7696), 371-376, 2018	809	2018
Whole-genome and epigenomic landscapes of etiologically distinct subtypes of cholangiocarcinoma A Jusakul, I Cutcutache, CH Yong, JQ Lim, MN Huang, N Padmanabhan, ... Cancer discovery 7 (10), 1116-1135, 2017	801	2017
Genomic evolution of breast cancer metastasis and relapse LR Yates, S Knappskog, D Wedge, JHR Farmery, S Gonzalez, ... Cancer cell 32 (2), 169-184. e7, 2017	691	2017
A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns F Notta, M Chan-Seng-Yue, M Lemire, Y Li, GW Wilson, AA Connor, ... Nature 538, 378–382, 2016	590	2016

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