Ludmil B. Alexandrov

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David C WedgeProfessor of Cancer Genomics and Data Science, University of ManchesterVerified email at manchester.ac.uk
Erik N. BergstromUniversity of California, San DiegoVerified email at eng.ucsd.edu
Inigo MartincorenaWellcome Sanger InstituteVerified email at sanger.ac.uk
Boian S. AlexandrovTheoretical Division, Los Alamos National LabVerified email at lanl.gov
Dmitry GordeninPI, Mechanisms of Genome Dynamics Group, NIEHSVerified email at niehs.nih.gov
Kim O. RasmussenTheoretical Division, Los Alamos National LaboratoryVerified email at lanl.gov
Anny UshevaProfessor (associate) of SurgeryVerified email at brown.edu
Mia PetljakBroad Institute of MIT and HarvardVerified email at broadinstitute.org
John R McPhersonAssociate in Research, Centre for Computational Biology, Duke-NUS Graduate Medical SchoolVerified email at duke-nus.edu.sg
Arnoud BootGenomeScan B.V.Verified email at genomescan.nl
Nicholas J HaradhvalaThe Broad InstituteVerified email at broadinstitute.org
David A. WheelerBaylor College of MedicineVerified email at bcm.edu
Ville MustonenUniversity of HelsinkiVerified email at helsinki.fi
Kyle CovingtonCastle Biosciences Inc, Friendswood TXVerified email at castlebiosciences.com
Jose M. C. TubioMolecular Medicine and Chronic diseases Centre (CIMUS), University of Santiago de CompostelaVerified email at usc.es
Jayendra ShindeCrosscope Inc.Verified email at crosscope.com
Steven G. RozenDuke-NUS Medical School SingaporeVerified email at duke-nus.edu.sg
Anthony FullamEMBLVerified email at embl.de
Jessica Zucman-RossiUniversité Paris Cité, AP-HPVerified email at inserm.fr
Eric LetouzéSenior Researcher, INSERM U1162Verified email at inserm.fr

Ludmil B. Alexandrov

Associate Professor, University of California San Diego

Verified email at ucsd.edu - Homepage

Computational Biology Cancer Genomics Mutagenesis Ageing Bioinformatics


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Signatures of mutational processes in human cancer LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ... Nature 500 (7463), 415-421, 2013	9038	2013
The repertoire of mutational signatures in human cancer LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AW Tian Ng, Y Wu, ... Nature 578 (7793), 94-101, 2020	1942	2020
Landscape of somatic mutations in 560 breast cancer whole-genome sequences S Nik-Zainal, H Davies, J Staaf, M Ramakrishna, D Glodzik, X Zou, ... Nature 534 (7605), 47-54, 2016	1911	2016
Mutational Processes Molding the Genomes of 21 Breast Cancers S Nik-Zainal, LB Alexandrov, DC Wedge, P Van Loo, CD Greenman, ... Cell 149 (5), 979-993, 2012	1906	2012
High burden and pervasive positive selection of somatic mutations in normal human skin I Martincorena, A Roshan, M Gerstung, P Ellis, P Van Loo, S McLaren, ... Science 348 (6237), 880-886, 2015	1506	2015
Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets K Schulze, S Imbeaud, E Letouzé, LB Alexandrov, J Calderaro, ... Nature Genetics 47 (5), 505–511, 2015	1450	2015
The Life History of 21 Breast Cancers S Nik-Zainal, P Van Loo, DC Wedge, LB Alexandrov, CD Greenman, ... Cell 149 (5), 994-1007, 2012	1449	2012
The evolutionary history of lethal metastatic prostate cancer G Gundem, P Van Loo, B Kremeyer, LB Alexandrov, JMC Tubio, ... Nature 520 (7547), 353–357, 2015	1300	2015
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020	1139	2020
Deciphering Signatures of Mutational Processes Operative in Human Cancer LB Alexandrov, S Nik-Zainal, DC Wedge, PJ Campbell, MR Stratton Cell Reports 3 (1), 246-259, 2013	1131	2013
Whole-genome landscapes of major melanoma subtypes NK Hayward, JS Wilmott, N Waddell, PA Johansson, MA Field, K Nones, ... Nature 545, 175–180, 2017	1075	2017
Mutational signatures associated with tobacco smoking in human cancer LB Alexandrov, YS Ju, K Haase, P Van Loo, I Martincorena, S Nik-Zainal, ... Science 354 (6312), 618-622, 2016	895	2016
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma N Bolli, H Avet-Loiseau, DC Wedge, P Van Loo, LB Alexandrov, ... Nature Communications 5 (2997), 2014	895	2014
Clock-like mutational processes in human somatic cells LB Alexandrov, PH Jones, DC Wedge, JE Sale, PJ Campbell, ... Nature Genetics 47 (12), 1402–1407, 2015	865	2015
Timing, rates and spectra of human germline mutation R Rahbari, A Wuster, SJ Lindsay, RJ Hardwick, LB Alexandrov, S Al Turki, ... Nature Genetics 48, 126–133, 2016	817	2016
Subclonal diversification of primary breast cancer revealed by multiregion sequencing LR Yates, M Gerstung, S Knappskog, C Desmedt, G Gundem, P Van Loo, ... Nature Medicine 21 (7), 751-759, 2015	756	2015
Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of CholangiocarcinomaIntegrative Genomic and Epigenomic Analysis of Cholangiocarcinoma A Jusakul, I Cutcutache, CH Yong, JQ Lim, MN Huang, N Padmanabhan, ... Cancer discovery 7 (10), 1116-1135, 2017	598	2017
Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours X Ma, YU Liu, Y Liu, LB Alexandrov, MN Edmonson, C Gawad, X Zhou, ... Nature 555 (7696), 371-376, 2018	595	2018
Genomic evolution of breast cancer metastasis and relapse LR Yates, S Knappskog, D Wedge, JHR Farmery, S Gonzalez, ... Cancer cell 32 (2), 169-184. e7, 2017	573	2017
Mutational signatures: the patterns of somatic mutations hidden in cancer genomes LB Alexandrov, MR Stratton Current Opinion in Genetics & Development 24, 52-60, 2014	509	2014

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