Erik Fredlund
Erik Fredlund
Dept. Oncology-Pathology, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden
Verified email at ki.se
Title
Cited by
Cited by
Year
Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype
L Holmquist-Mengelbier, E Fredlund, T Löfstedt, R Noguera, S Navarro, ...
Cancer cell 10 (5), 413-423, 2006
6632006
Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development
P Kucharzewska, HC Christianson, JE Welch, KJ Svensson, E Fredlund, ...
Proceedings of the National Academy of Sciences 110 (18), 7312-7317, 2013
5592013
Hypoxia-induced dedifferentiation of tumor cells–a mechanism behind heterogeneity and aggressiveness of solid tumors
H Axelson, E Fredlund, M Ovenberger, G Landberg, S Påhlman
Seminars in cell & developmental biology 16 (4-5), 554-563, 2005
3112005
GOBO: gene expression-based outcome for breast cancer online
M Ringnér, E Fredlund, J Häkkinen, Å Borg, J Staaf
PloS one 6 (3), e17911, 2011
3092011
The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma
P Mestdagh, AK Boström, F Impens, E Fredlund, G Van Peer, ...
Molecular cell 40 (5), 762-773, 2010
2852010
Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia
HY Fang, R Hughes, C Murdoch, SB Coffelt, SK Biswas, AL Harris, ...
Blood, The Journal of the American Society of Hematology 114 (4), 844-859, 2009
2372009
The mutational landscapes of genetic and chemical models of Kras-driven lung cancer
PMK Westcott, KD Halliwill, MD To, M Rashid, AG Rust, TM Keane, ...
Nature 517 (7535), 489-492, 2015
2262015
Hypoxia inducible factor-2α in cancer
T Löfstedt, E Fredlund, L Holmquist-Mengelbier, A Pietras, M Ovenberger, ...
Cell cycle 6 (8), 919-926, 2007
2032007
High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma
E Fredlund, M Ringnér, JM Maris, S Påhlman
Proceedings of the National Academy of Sciences 105 (37), 14094-14099, 2008
1522008
An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours
P Mestdagh, E Fredlund, F Pattyn, A Rihani, T Van Maerken, J Vermeulen, ...
Oncogene 29 (24), 3583-3592, 2010
1412010
HIF-2α maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells
A Pietras, LM Hansford, AS Johnsson, E Bridges, J Sjölund, D Gisselsson, ...
Proceedings of the National Academy of Sciences 106 (39), 16805-16810, 2009
1412009
MYCN-regulated microRNAs repress estrogen receptor-α (ESR1) expression and neuronal differentiation in human neuroblastoma
J Lovén, N Zinin, T Wahlström, I Müller, P Brodin, E Fredlund, U Ribacke, ...
Proceedings of the National Academy of Sciences 107 (4), 1553-1558, 2010
1342010
Hypoxia-inducible factor-2α correlates to distant recurrence and poor outcome in invasive breast cancer
K Helczynska, AM Larsson, LH Mengelbier, E Bridges, E Fredlund, ...
Cancer research 68 (22), 9212-9220, 2008
1322008
MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors
P Mestdagh, E Fredlund, F Pattyn, JH Schulte, D Muth, J Vermeulen, ...
Oncogene 29 (9), 1394-1404, 2010
1312010
Pericyte–fibroblast transition promotes tumor growth and metastasis
K Hosaka, Y Yang, T Seki, C Fischer, O Dubey, E Fredlund, J Hartman, ...
Proceedings of the National Academy of Sciences 113 (38), E5618-E5627, 2016
982016
PARP1-and CTCF-mediated interactions between active and repressed chromatin at the lamina promote oscillating transcription
H Zhao, EG Sifakis, N Sumida, L Millán-Ariño, BA Scholz, JP Svensson, ...
Molecular cell 59 (6), 984-997, 2015
862015
Molecular stratification of metastatic melanoma using gene expression profiling: Prediction of survival outcome and benefit from molecular targeted therapy
H Cirenajwis, H Ekedahl, M Lauss, K Harbst, A Carneiro, J Enoksson, ...
Oncotarget 6 (14), 12297, 2015
822015
HIF-1α and HIF-2α are differentially regulated in vivo in neuroblastoma: high HIF-1α correlates negatively to advanced clinical stage and tumor vascularization
R Noguera, E Fredlund, M Piqueras, A Pietras, S Beckman, S Navarro, ...
Clinical cancer research 15 (23), 7130-7136, 2009
752009
The microRNA body map: dissecting microRNA function through integrative genomics
P Mestdagh, S Lefever, F Pattyn, D Ridzon, E Fredlund, A Fieuw, ...
Nucleic acids research 39 (20), e136-e136, 2011
742011
Notch signaling in neuroblastoma
S Påhlman, MT Stockhausen, E Fredlund, H Axelson
Seminars in cancer biology 14 (5), 365-373, 2004
672004
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