| Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of … C Burger, OS Gorbatyuk, MJ Velardo, CS Peden, P Williams, S Zolotukhin, ... Molecular Therapy 10 (2), 302-317, 2004 | 901 | 2004 |
| Parkinson-like neurodegeneration induced by targeted overexpression of α-synuclein in the nigrostriatal system D Kirik, C Rosenblad, C Burger, C Lundberg, TE Johansen, N Muzyczka, ... Journal of Neuroscience 22 (7), 2780-2791, 2002 | 893 | 2002 |
| CoREST: a functional corepressor required for regulation of neural-specific gene expression ME Andrés, C Burger, MJ Peral-Rubio, E Battaglioli, ME Anderson, ... Proceedings of the National Academy of Sciences 96 (17), 9873-9878, 1999 | 579 | 1999 |
| Regulation of neuronal traits by a novel transcriptional complex N Ballas, E Battaglioli, F Atouf, ME Andres, J Chenoweth, ME Anderson, ... Neuron 31 (3), 353-365, 2001 | 510 | 2001 |
| Nigrostriatal α-synucleinopathy induced by viral vector-mediated overexpression of human α-synuclein: a new primate model of Parkinson's disease D Kirik, LE Annett, C Burger, N Muzyczka, RJ Mandel, A Björklund Proceedings of the National Academy of Sciences 100 (5), 2884-2889, 2003 | 487 | 2003 |
| Continuous low-level glial cell line-derived neurotrophic factor delivery using recombinant adeno-associated viral vectors provides neuroprotection and induces behavioral … A Eslamboli, B Georgievska, RM Ridley, HF Baker, N Muzyczka, C Burger, ... Journal of Neuroscience 25 (4), 769-777, 2005 | 271 | 2005 |
| Circulating anti-wild-type adeno-associated virus type 2 (AAV2) antibodies inhibit recombinant AAV2 (rAAV2)-mediated, but not rAAV5-mediated, gene transfer in the brain CS Peden, C Burger, N Muzyczka, RJ Mandel Journal of virology 78 (12), 6344-6359, 2004 | 251 | 2004 |
| Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain A Eslamboli, M Romero-Ramos, C Burger, T Bjorklund, N Muzyczka, ... Brain 130 (3), 799-815, 2007 | 245 | 2007 |
| Metabolic regulation of neuronal plasticity by the energy sensor AMPK WB Potter, KJ O'Riordan, D Barnett, SMK Osting, M Wagoner, C Burger, ... PloS one 5 (2), e8996, 2010 | 202 | 2010 |
| Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of l-dopa using rAAV-mediated gene transfer D Kirik, B Georgievska, C Burger, C Winkler, N Muzyczka, RJ Mandel, ... Proceedings of the National Academy of Sciences 99 (7), 4708-4713, 2002 | 165 | 2002 |
| Recombinant adeno-associated viral vectors as therapeutic agents to treat neurological disorders RJ Mandel, FP Manfredsson, KD Foust, A Rising, S Reimsnider, K Nash, ... Molecular Therapy 13 (3), 463-483, 2006 | 159 | 2006 |
| Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome YS Lee, D Ehninger, M Zhou, JY Oh, M Kang, C Kwak, HH Ryu, D Butz, ... Nature neuroscience 17 (12), 1736-1743, 2014 | 148 | 2014 |
| Recombinant adeno-associated viral vectors in the nervous system C Burger, K Nash, RJ Mandel Human gene therapy 16 (7), 781-791, 2005 | 147 | 2005 |
| Patterns of gene expression reveal a temporally orchestrated wound healing response in the injured spinal cord MJ Velardo, C Burger, PR Williams, HV Baker, MC López, TH Mareci, ... Journal of Neuroscience 24 (39), 8562-8576, 2004 | 116 | 2004 |
| Reversal of Fragile X Phenotypes by Manipulation of AβPP/Aβ Levels in Fmr1KO Mice CJ Westmark, PR Westmark, KJ O'Riordan, BC Ray, CM Hervey, ... PloS one 6 (10), e26549, 2011 | 115 | 2011 |
| Clinical trials in neurological disorders using AAV vectors: promises and challenges. RJ Mandel, C Burger Current opinion in molecular therapeutics 6 (5), 482-490, 2004 | 115 | 2004 |
| Recombinant adeno-associated viral vector (rAAV) delivery of GDNF provides protection against 6-OHDA lesion in the common marmoset monkey (Callithrix jacchus) A Eslamboli, RM Cummings, RM Ridley, HF Baker, N Muzyczka, C Burger, ... Experimental neurology 184 (1), 536-548, 2003 | 107 | 2003 |
| Reversal of dyskinesias in an animal model of Parkinson's disease by continuous l-DOPA delivery using rAAV vectors T Carlsson, C Winkler, C Burger, N Muzyczka, RJ Mandel, A Cenci, ... Brain 128 (3), 559-569, 2005 | 106 | 2005 |
| Production of pseudotyped recombinant AAV virions RO Snyder, S Zolotukhin, Y Sakai, BJ Byrne, MR Potter, I Zolotukhin, ... US Patent 7,094,604, 2006 | 100 | 2006 |
| Production of pseudotyped recombinant AAV virions RO Snyder, S Zolotukhin, Y Sakai, BJ Byrne, MR Potter, I Zolotukhin, ... US Patent 7,094,604, 2006 | 100 | 2006 |
