Georg E Winter
Georg E Winter
Principal Investigator at CeMM, Vienna
Verified email at - Homepage
Cited by
Cited by
Phthalimide conjugation as a strategy for in vivo target protein degradation
GE Winter, DL Buckley, J Paulk, JM Roberts, A Souza, S Dhe-Paganon, ...
Science 348 (6241), 1376-1381, 2015
Human haploid cell genetics reveals roles for lipid metabolism genes in nonapoptotic cell death
SJ Dixon, GE Winter, LS Musavi, ED Lee, B Snijder, M Rebsamen, ...
ACS chemical biology 10 (7), 1604-1609, 2015
The dTAG system for immediate and target-specific protein degradation
B Nabet, JM Roberts, DL Buckley, J Paulk, S Dastjerdi, A Yang, ...
Nature chemical biology 14 (5), 431-441, 2018
Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation
CM Olson, B Jiang, MA Erb, Y Liang, ZM Doctor, Z Zhang, T Zhang, ...
Nature chemical biology 14 (2), 163-170, 2018
BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment
GE Winter, A Mayer, DL Buckley, MA Erb, JE Roderick, S Vittori, JM Reyes, ...
Molecular cell 67 (1), 5-18. e19, 2017
Suv39h-dependent H3K9me3 marks intact retrotransposons and silences LINE elements in mouse embryonic stem cells
A Bulut-Karslioglu, A Inti, F Ramirez, M Barenboim, M Onishi-Seebacher, ...
Molecular cell 55 (2), 277-290, 2014
Transcription control by the ENL YEATS domain in acute leukaemia
MA Erb, TG Scott, BE Li, H Xie, J Paulk, HS Seo, A Souza, JM Roberts, ...
Nature 543 (7644), 270-274, 2017
Rational discovery of molecular glue degraders via scalable chemical profiling
C Mayor-Ruiz, S Bauer, M Brand, Z Kozicka, M Siklos, H Imrichova, ...
Nature chemical biology 16 (11), 1199-1207, 2020
Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands
LN Gechijian, DL Buckley, MA Lawlor, JM Reyes, J Paulk, CJ Ott, ...
Nature chemical biology 14 (4), 405-412, 2018
Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML
M Brand, B Jiang, S Bauer, KA Donovan, Y Liang, ES Wang, RP Nowak, ...
Cell chemical biology 26 (2), 300-306. e9, 2019
Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma
R Zeid, MA Lawlor, E Poon, JM Reyes, M Fulciniti, MA Lopez, TG Scott, ...
Nature genetics 50 (4), 515-523, 2018
The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity
GE Winter, B Radic, C Mayor-Ruiz, VA Blomen, C Trefzer, RK Kandasamy, ...
Nature chemical biology 10 (9), 768-773, 2014
LZTR1 is a regulator of RAS ubiquitination and signaling
JW Bigenzahn, GM Collu, F Kartnig, M Pieraks, GI Vladimer, LX Heinz, ...
Science 362 (6419), 1171-1177, 2018
Translation termination factor GSPT1 is a phenotypically relevant off-target of heterobifunctional phthalimide degraders
M Ishoey, S Chorn, N Singh, MG Jaeger, M Brand, J Paulk, S Bauer, ...
ACS Chemical Biology 13 (3), 553-560, 2018
Acute BAF perturbation causes immediate changes in chromatin accessibility
S Schick, S Grosche, KE Kohl, D Drpic, MG Jaeger, NC Marella, ...
Nature genetics 53 (3), 269-278, 2021
Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML
GE Winter, U Rix, SM Carlson, KV Gleixner, F Grebien, M Gridling, ...
Nature chemical biology 8 (11), 905-912, 2012
Targetable BET proteins-and E2F1-dependent transcriptional program maintains the malignancy of glioblastoma
L Xu, Y Chen, A Mayakonda, L Koh, YK Chong, DL Buckley, ...
Proceedings of the National Academy of Sciences 115 (22), E5086-E5095, 2018
MELK is not necessary for the proliferation of basal-like breast cancer cells
HT Huang, HS Seo, T Zhang, Y Wang, B Jiang, Q Li, DL Buckley, B Nabet, ...
Elife 6, e26693, 2017
Methods to induce targeted protein degradation through bifunctional molecules
J Bradner, D Buckley, G Winter
US Patent 9,694,084, 2017
Targeted protein degradation: current and future challenges
A Hanzl, GE Winter
Current opinion in chemical biology 56, 35-41, 2020
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