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Lesley Jones
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Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ...
Nature genetics 45 (12), 1452-1458, 2013
46062013
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nature genetics 51 (3), 414-430, 2019
25072019
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
P Hollingworth, D Harold, R Sims, A Gerrish, JC Lambert, ...
Nature genetics 43 (5), 429-435, 2011
22552011
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
Nature Genetics 49 (9), 1373-1384, 2017
9632017
Regional and cellular gene expression changes in human Huntington's disease brain
A Hodges, AD Strand, AK Aragaki, A Kuhn, T Sengstag, G Hughes, ...
Human molecular genetics 15 (6), 965-977, 2006
9172006
The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease
AN Packer, Y Xing, SQ Harper, L Jones, BL Davidson
Journal of Neuroscience 28 (53), 14341-14346, 2008
8222008
Huntington's disease
G Bates, S Tabrizi, L Jones
Oxford University Press, 2014
7142014
Susceptibility locus for Alzheimer's disease on chromosome 10
A Myers, P Holmans, H Marshall, J Kwon, D Meyer, D Ramic, S Shears, ...
Science 290 (5500), 2304-2305, 2000
4922000
Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease
L Jones, PA Holmans, ML Hamshere, D Harold, V Moskvina, D Ivanov, ...
PloS one 5 (11), e13950, 2010
4612010
Identification of genetic factors that modify clinical onset of Huntington’s disease
JM Lee, VC Wheeler, MJ Chao, JPG Vonsattel, RM Pinto, D Lucente, ...
Cell 162 (3), 516-526, 2015
4492015
Common polygenic variation enhances risk prediction for Alzheimer’s disease
V Escott-Price, R Sims, C Bannister, D Harold, M Vronskaya, E Majounie, ...
Brain 138 (12), 3673-3684, 2015
4482015
CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion
JM Lee, EM Ramos, JH Lee, T Gillis, JS Mysore, MR Hayden, SC Warby, ...
Neurology 78 (10), 690-695, 2012
4442012
Transgenic rat model of Huntington's disease
S von Hörsten, I Schmitt, HP Nguyen, C Holzmann, T Schmidt, T Walther, ...
Human molecular genetics 12 (6), 617-624, 2003
4232003
Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin …
A Kuhn, DR Goldstein, A Hodges, AD Strand, T Sengstag, C Kooperberg, ...
Human molecular genetics 16 (15), 1845-1861, 2007
3872007
Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin
JM Boutell, P Thomas, JW Neal, VJ Weston, J Duce, PS Harper, ...
Human molecular genetics 8 (9), 1647-1655, 1999
3751999
Helping patients with type 2 diabetes mellitus make treatment decisions: statin choice randomized trial
AJ Weymiller, VM Montori, LA Jones, A Gafni, GH Guyatt, SC Bryant, ...
Archives of internal medicine 167 (10), 1076-1082, 2007
3332007
CAG repeat not polyglutamine length determines timing of Huntington’s disease onset
JM Lee, K Correia, J Loupe, KH Kim, D Barker, EP Hong, MJ Chao, ...
Cell 178 (4), 887-900. e14, 2019
3252019
Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study
DJH Moss, AF Pardiñas, D Langbehn, K Lo, BR Leavitt, R Roos, A Durr, ...
The Lancet Neurology 16 (9), 701-711, 2017
3212017
A novel Alzheimer disease locus located near the gene encoding tau protein
G Jun, CA Ibrahim-Verbaas, M Vronskaya, JC Lambert, J Chung, AC Naj, ...
Molecular psychiatry 21 (1), 108-117, 2016
3012016
Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration
AD Strand, ZC Baquet, AK Aragaki, P Holmans, L Yang, C Cleren, ...
Journal of Neuroscience 27 (43), 11758-11768, 2007
2812007
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